The concept of functional preservation after orthotopic neobladder construction has gradually attracted attention. Reconstruction of urine storage and voiding is the basic function preservation of orthotopic neobladder. Clinical exploration mainly focuses on the optimization of neobladder reconstruction methods and procedures, and there is still a lack of summary of existing surgical characteristics and high-quality functional comparative studies. For strictly selected patients, on the basis of tumor control and standardized postoperative rehabilitation guidance, most patients with preserved nerve can retain satisfied sexual function after surgery. The protection of neurovascular bundle and ancillary structures combined with postoperative exercise is crucial to the improvement of urinary continence. According to the characteristics of patients, choosing the appropriate urinary diversion methods and function preserving can help patients establish a normal life style after surgery and improve their self-image and quality of life.
Humans ; Urinary Reservoirs, Continent/physiology* ; Cystectomy/methods* ; Urinary Bladder Neoplasms/surgery* ; Quality of Life ; Urinary Diversion/methods*

OBJECTIVETo investigate the long-term outcome and related complications in a group of patients underwent Studer neobladder surgery.

METHODSFrom may 2005 to Jan 2008, 25 patients with invasive bladder tumor underwent Studer procedure. Among of them, 20 patients were followed up from 6 to 44 months. Functional bladder capacity, residual urine, peak flow rate and incontinence in 3, 12, 24, 36 months following neobladder were evaluated. Surgical associated complications, death rate were included as well.

RESULTSThere was no significant difference in functional bladder capacity, peak flow rate after the procedure (P > 0.05), but there was significant difference in residual urine (36 ml vs 80 ml, P < 0.01). Hydronephrosis, renal atrophy, urinary infection and hematuria were major complications encountered in this study.

CONCLUSIONSThe procedure is safe, and satisfied urinary function is kept in the neobladder. The long-term outcome will be improved with accumulated experiences.

Adult ; Aged ; Cystectomy ; Female ; Follow-Up Studies ; Humans ; Ileum ; surgery ; Male ; Middle Aged ; Postoperative Complications ; Urinary Bladder Neoplasms ; surgery ; Urinary Diversion ; methods ; Urinary Incontinence ; etiology ; Urinary Reservoirs, Continent ; physiology ; Urination ; Urodynamics