No abstract available.
Diagnosis* ; Urinary Bladder Neoplasms* ; Urinary Bladder*

For making a diagnosis of bladder Ca. the comparative study was performed on 12 cases with bladder washings and urine in cytology by the routine papanicolaou stins, and all of those were con firmed by cystoscopic examination. Results are as follows: 1. Bladder washing Cytology showed better results than urine cytology in 8 of 12 patients. 2. Of those cases, the significant cases were 83% on bladder washing cytology and 25% on urine of bladder cancer. 3. Neoplastic cells were found in 10 cases of the bladder washings, instead of 4 cases of bladder urine.
Diagnosis* ; Humans ; Urinary Bladder Neoplasms* ; Urinary Bladder*

For making a diagnosis of bladder Ca. the comparative study was performed on 12 cases with bladder washings and urine in cytology by the routine papanicolaou stins, and all of those were con firmed by cystoscopic examination. Results are as follows: 1. Bladder washing Cytology showed better results than urine cytology in 8 of 12 patients. 2. Of those cases, the significant cases were 83% on bladder washing cytology and 25% on urine of bladder cancer. 3. Neoplastic cells were found in 10 cases of the bladder washings, instead of 4 cases of bladder urine.
Diagnosis* ; Humans ; Urinary Bladder Neoplasms* ; Urinary Bladder*

No abstract available.
Diagnosis* ; Urinary Bladder Neoplasms* ; Urinary Bladder*

Bladder cancer is a significant public health problem. Significant progress has been made in understanding the underlying molecular and genetic events in bladder cancer. However, there remains a great need for the development of reliable markers that can provide clinically useful information regarding diagnosis and prognosis and to facillitate the selection of appropriate therapy in individual patients. Ongoing and future investigation is anticipated to refine treatment of patients with bladder cancer
Urinary Bladder Neoplasms ; diagnosis ; Therapeutics

Spontaneous bladder perforation is a very rare event. Prompt diagnosis of this injury is very important, particularly with intraperitoneal perforation, because mortality increases if surgical repair is delayed. Previous studies have reported that plain cystography is the primary modality of imaging study rather than relatively insensitive computed tomography (CT) when bladder perforation is suspected. We report here a rare case of spontaneous intraperitoneal perforation of the bladder associated with urothelial carcinoma with divergent histologic differentiation, as diagnosed with CT cystography.
Diagnosis, Differential ; Rupture, Spontaneous ; Urinary Bladder ; Urinary Bladder Neoplasms

Primary neoplasms arising in vesical diverticula are rare and present special problems in diagnosis and treatment. We report a case of primary carcinoma arising in vesical diverticula with associated benign prostatic hypertrophy.
Diagnosis ; Diverticulum* ; Prostatic Hyperplasia ; Urinary Bladder Neoplasms

Bladder cancer (BC) is the most common malignant tumor of the genitourinary system. The age of individuals diagnosed with BC tends to decrease in recent years. A variety of standard therapeutic options are available for the clinical management of BC, but limitations exist. It is difficult to surgically eliminate small lesions, while radiation and chemotherapy damage normal tissues, leading to severe side effects. Therefore, new approaches are required to improve the efficacy and specificity of BC treatment. Synthetic biology is a field emerging in the last decade that refers to biological elements, devices, and materials that are artificially synthesized according to users' needs. In this review, we discuss how to utilize genetic elements to regulate BC-related gene expression periodically and quantitatively to inhibit the initiation and progression of BC. In addition, the design and construction of gene circuits to distinguish cancer cells from normal cells to kill the former but spare the latter are elaborated. Then, we introduce the development of genetically modified T cells for targeted attacks on BC. Finally, synthetic nanomaterials specializing in detecting and killing BC cells are detailed. This review aims to describe the innovative details of the clinical diagnosis and treatment of BC from the perspective of synthetic biology.
Humans ; Synthetic Biology ; Urinary Bladder Neoplasms/diagnosis*

Under specific circumstances the appendix vermiformis may be an appropriate organ for replacement of a large ureteral defect or efferent loop in continent urinary diversion. Since 1995 we have applied the appendix in ureteral substitution (3 cases) and continent urinary diversion (3 cases). Primary diagnoses included complete lower ureteral stricture due to urinary tuberculosis (3 cases), invasive bladder tumor (1 case), areflexic neurogenic bladder (1 case), and contracted bladder (1 case). In all patients who have been replaced the ureter with appendix, clinical symptoms were markedly improved and degree of hydronephrosis decreased. Other patients with continent urinary diversion using appendix achieved dryness and low postoperative complications. we anticipate that the appendix will be used more commonly in the future as a ureteral substitute or continent urinary diversion as more urologists become more comfortable with it through its use in various reconstructive procedures.
Appendix* ; Constriction, Pathologic ; Diagnosis ; Humans ; Hydronephrosis ; Postoperative Complications ; Tuberculosis ; Ureter ; Urinary Bladder ; Urinary Bladder Neoplasms ; Urinary Bladder, Neurogenic ; Urinary Diversion

It has been recognized for many years that a proportion of patients with bladder cancer have their tumors caused by past exposure at work to carcinogenic aromatic amines. All patients attending the Department of Urology Yonsei University Hospital with bladder cancer during the period from August, 1981 to July, 1983 are routinely interviewed and full occupational histories are taken. One use of the histories collected has been to identify patients with occupational tumors. This study has designed to provide information regarding the value of cytologic examination of urinary tract specimen in the early detection and mass screening in cases of bladder cancer. Two hundred fifty two patients were subjected to this study. These patients have taken cytologic examinations at the Department of Urology, Yonsei University Hospital during the same period. The series compromised 156 consecutive cases without clinically or histologically verified bladder cancer and 96 consecutive cases of histologically verified transitional cell neoplasms of the bladder. Following results were obtained according to the various analyses. 1) There were 75 positive tests from patients with proved cancer(78.1%). 13 false positive cytological diagnoses malignancy were made in the 156 patients without bladder cancer(8.3%). It showed that cytological study is useful in the early detection and mass screening of bladder cancer. 2) The diagnostic accuracy of urinary cytology appears to be related to the quality of cytological preparations and the histological grade of bladder cancer. The frequency of positive findings in cases of grade II(79.6%) was much higher than that of grade I (42.9%). 3) 10.4% of patients gave their histories which suggested relevant occupations with possible exposure to carcinogen.
Amines ; Diagnosis ; Humans ; Mass Screening ; Occupational Health* ; Occupations ; Urinary Bladder ; Urinary Bladder Neoplasms ; Urinary Tract ; Urology