No abstract available.
Uremia*

No abstract available.
Uremia*

No abstract available.
Atypical Hemolytic Uremic Syndrome* ; Complement C3* ; Complement System Proteins*

93 cases of hyperuremia were treated by the “Thong Phong hoan”, a traditional formula at the Military Institute of Traditional Medicine. Among them, patients with hyperuremia and gout were 40-60 year old, occupied a part of 70%, 94.6% in male and 5.4% in female. 76.4% of cases had got 1-5 year duration of the disease, 12.9% > 5 years old and 2.1% > 10 years old. Consuming much of alcohol, meat and abusing tobaco were the common habits of studied male patients. After 30 days of treatment, the preparation exerted the effect of dramatical decrease of uremia, with good results 76.3%, medium 18.3%, bad 5.4%.
Medicine, Traditional ; Uremia

The kidneys play a vital role in the maintenance of normal body fluid volumes and in the composition of the extracellular fluid compartments. There are normally more than 2 million functioning glomeruli that regulate total body water and solute concentrations. As renal failure progresses, there is a decrease in the number of functioning nephrons. Chronic renal failure(CRF) is the consequence of a multitude of diseases that cause permanent destruction of the nephron. Azotemia is an elevation in blood urea nitrogen(BUN) and serum creatinine levels subsequent to a decreased glomerular filtration rate(GFR), which results in uremia. This loss of renal function can cause functional and metabolic abnomalities of body. For this problem, oral & maxillofacial surgeons have demanded to routinely treat patients with CRF. However, there has not been a reported case of orthognathic surgery by bilateral sagittal split ramus osteotomy(BSSRO) in patients with CRF, which can cause multiple complications in healthy patients. We report developmental mechanism of complication associated with CRF and preop. and postop. care of orthognathic surgery by BSSRO in ClIII patient with severe chronic renal failure.
Azotemia ; Body Fluids ; Body Water ; Creatinine ; Extracellular Fluid ; Filtration ; Humans ; Kidney ; Kidney Failure, Chronic* ; Nephrons ; Orthognathic Surgery ; Renal Insufficiency ; Urea ; Uremia

Hemolytic-uremic syndrome (HUS) is the most common cause of acute renal failure in young children. It is classically characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and uremia. Further, not only is intussusception one of the differential diagnoses of HUS but it may also become a complication during disease progression. We report a case of HUS preceded by intussusception in a previously healthy 17-month-old boy. The patient presented at the emergency department with bloody stools that developed the day after reduction of intussusception. HUS was diagnosed 4 days after the reduction of intussusception. The patient was provided only supportive care and his laboratory test findings were normal at discharge.
Acute Kidney Injury ; Anemia, Hemolytic ; Child ; Diagnosis, Differential ; Disease Progression ; Emergencies ; Hemolytic-Uremic Syndrome ; Humans ; Infant ; Intussusception ; Thrombocytopenia ; Uremia

Adult ; Atypical Hemolytic Uremic Syndrome ; etiology ; Female ; Glomerulonephritis, IGA ; complications ; Humans ; Puerperal Disorders ; etiology

Antibodies, Monoclonal, Humanized/therapeutic use* ; Atypical Hemolytic Uremic Syndrome/drug therapy* ; Humans

Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is mainly plasmapheresis or plasma infusion; however, many children with aHUS will progress to chronic kidney disease despite plasma therapy. Eculizumab is a newly developed biologic that blocks the terminal complement pathway and has been successfully used in the treatment of aHUS. Currently, several guidelines for aHUS, including the Korean guideline, recommend eculizumab as the first-line therapy in children with aHUS. Moreover, life-long eculizumab therapy is generally recommended. Further studies on discontinuation of eculizumab are needed.
Acute Kidney Injury ; Atypical Hemolytic Uremic Syndrome ; Child ; Complement System Proteins ; Escherichia ; Hemolytic-Uremic Syndrome ; Humans ; Kidney Failure, Chronic ; Plasma ; Plasmapheresis ; Renal Insufficiency, Chronic ; Stroke

We report a case of hemolytic uremic syndrome (HUS) associated with hemorrhagic colitis. A 35-year-old man was admitted to a local hospital because of abdominal pain and watery diarrhea that had developed about 6 hours after taking roast beef. He was treated with intravenous fluids and antibiotics, but watery diarrhea changed to bloody in nature from the next day. He was transferred to our hospital due to progressive ascites and jaundice on his 8th day of illness. Examinations revealed ascites, jaundice, microangiopathic hemolytic anemia, thrombocytopenia and uremia. Sorbitol-negative Escherichia coli was isolated from his stool, which proved as Shiga-like toxin-negative E. coli, serotype O25. His conditions improved markedly after three times of plasmapheresis and intravenous fluid therapy, and the organism was not isolated from the follow-up stool culture.
Abdominal Pain ; Adult ; Anemia, Hemolytic ; Anti-Bacterial Agents ; Ascites ; Colitis* ; Diarrhea ; Escherichia coli ; Fluid Therapy ; Follow-Up Studies ; Hemolytic-Uremic Syndrome* ; Humans ; Jaundice ; Plasmapheresis ; Thrombocytopenia ; Uremia