IntroductionWe organized the 4th Mongolian External Quality Assessment Survey (MEQAS) for Clinical Chemistry testing on basis of the Cooperation agreement between the Ministry of Health Mongolia and Sysmex Corporation in the establishment of the clinical chemistry external quality control, and reference laboratory system in 2011-2013.MethodIn 4th survey, the following survey material we used: Mtrol 1 (Level 1), Mtrol 2 (Level 2). To evaluate participant laboratories we divided into peer groups: full automated analyzer, semi automated analyzer and also divided analyzers by manufacturers and calculate standard deviation index (SDI), precision index (PI). We used absolute evaluation and scoring methods.ResultsThe number of participant laboratories increased in number by 133 instruments from 3rd MEQAS and became 139 instruments, but there were no significant improvements in most all items. The comparison transition of CV 4th MEQAS to 3rd MEQAS we found that there were not much differences between before the 3rd and 4th MEQAS, except some items like total protein, Lactate dehydrogenase (P-L), γ-Glutamyl transferase, potassium, bilirubin direct in which CV % have decreased in number by about 3% from 10% in both levels. We found out the difference results between full automated analyzer, semi automated analyzer groups and manufacturer analyzers and methods in both levels. To improve the results in the future to establish national standards for the reporting units and suggested reagents for clinical chemistry tests, which will be the directions for standardization.

Introduction: Among women with Polycystic Ovarian Syndrome (PCOS), obesity is one of the diagnosis criteria and it is evaluated by waist circumference. We aimed to determine the measurement of waist circumference in women with PCOS. Obesity and PCOS tend to increase throughout the world. In 1994, leptin was discovered to be directly related to body mass index in obesity. Ovarian cystic syndrome has been shown to be associated with leptin levels and also that indicating the need for prevention of obesity in women. Objective: Clinical and medical determination for the waist circumference of women with PCOS and comporation study to leptin and comparative study to leptin levels. Мaterial and Methods: This research included a total of 86 women aged 18-35 in Ulaanbaatar city. We took a permission to start the research at the meeting of the Research Ethics Council of the Mongolian National University of Medical Sciences on March 22, 2019. Statistical analysis of this study results was performed using SPSS 19.0, text recording using Microsoft Office 2018 software, T-test to exclude group differences, ANOVA test for differences between more than two groups, and p<0.05 statistical probability difference. Results: The research of the 56 women tested for leptin in the serum of women with PCOS, 28 (32.5%) had a normal BMI with PCOS and 28 (32.5%) had an excess of BMI with PCOS, respectively. The mean levels of leptin was 13.86±11.40 kg/ml for people with normal BMI, PCOS and 33.78±17.63 kg/ml for people with excess BMI, PCOS. Leptin is higher in women with BMI, PCOS and this result is statistically significant (P-value 0.000). Conclusion Leptin levels are higher during PCOS, and leptin levels increase as the number of risk factors increases. Leptin secretion is affected by BMI and waist circumference.