1.Initial Experiences of Left Bundle Branch Area Pacing in Daegu, South Korea – New Procedure with Familiar Tools
Keimyung Medical Journal 2023;42(1):27-37
Implantation of a permanent pacemaker is a safe and effective treatment for symptomatic bradycardia. Conventionally, ventricular lead is placed at the right ventricular (RV) muscles. Therefore, this causes interventricular dyssynchrony, and long-term high RV pacing (RVP) burden is associated with an increased risk of heart failure and atrial fibrillation. Hence, attempts to directly pace the cardiac conduction system have been made, and finally, a technique called left bundle branch area pacing (LBBAP) has emerged. In our country, the clinical experience of LBBAP is in the early stages. Especially, LBBAP using standard stylet-driven leads (SDL), a major procedural method performed in our country, is also in the early stages, and there are only a few reports about this method worldwide. Herein, we are reporting our initial experiences of LBBAP with SDL. Compared to conventional RVP performed during the same period, LBBAP required an initial learning period a more extended procedure, and fluoroscopy time. However, the paced QRS duration was significantly shorter in the LBBAP group (LBBAP group 120.6 ± 13.0 msec, RVP group 165.2 ± 16.0 msec, p < 0.001). It is fascinating that simply adding a ventricular lead delivery sheath can create a whole new outcome, even at centers that are only familiar with the standard tools. Our experience will be helpful in arrhythmia centers that aim to start LBBAP for the first time.
2.Effect on sinus cycle length and atrioventricular node function after high‑power short‑duration versus conventional radiofrequency catheter ablation in paroxysmal atrial fibrillation
Ungjeong DO ; Minsoo KIM ; Min Soo CHO ; Gi‑Byoung NAM ; Kee‑Joon CHOI ; Jun JUN
International Journal of Arrhythmia 2022;23(2):12-
Background:
The efficacy and safety of high-power, short-duration (HPSD) radiofrequency catheter ablation for atrial fibrillation (AF) have been demonstrated in several studies. We aimed to evaluate and compare the effects of the conventional method and the HPSD method for AF ablation on the sinus and AV node function in patients with paroxysmal AF.
Methods:
The medical records of patients with paroxysmal AF who underwent pulmonary vein isolation (PVI) were retrieved from a prospectively collected AF ablation registry at a large-sized tertiary center. The HPSD group (n = 41) was distinguished from the conventional ablation group (n = 198) in terms of the power (50 W vs. 20–40 W) and dura‑ tion (6–10 s vs. 20–30 s) of radiofrequency energy delivery during PVI. Peri-procedural changes in cardiac autonomy were assessed in terms of the changes in sinus cycle length (SCL), block cycle length (BCL), and effective refractory period (ERP) of the atrioventricular node (AVN).
Results:
The SCL, BCL, and ERP of the AVN at baseline and post-ablation were not significantly different between the conventional ablation group and the HPSD group. Shortening of the SCL, BCL, and ERP of the AVN was observed immediately after AF ablation in both groups. One-year recurrence of AF/atrial flutter (35.1% vs. 20.3%; P = 0.011) and atrial flutter (13.8% vs. 4.7%; P = 0.015) were higher in the HPSD group than in the conventional ablation group.
Conclusion
Both the HPSD and the conventional ablation method resulted in post-ablation vagal modification as evidenced by the shortening of SCL, BCL, and ERP of the AVN. One-year recurrence of atrial flutter and AF/atrial flutter was higher in patients who underwent the HPSD method.
3.Esophageal Thermal Injury after Catheter Ablation for Atrial Fibrillation with High-Power (50 Watts) Radiofrequency Energy
Ungjeong DO ; Jun KIM ; Minsoo KIM ; Min Soo CHO ; Gi-Byoung NAM ; Kee-Joon CHOI ; You-Ho KIM
Korean Circulation Journal 2021;51(2):143-153
Background and Objectives:
Data regarding the safety of atrial fibrillation (AF) ablation using high-power (50 W) radiofrequency (RF) energy in Asian populations are limited. This study was conducted to evaluate the incidence and pattern of esophageal injury after highpower AF ablation in an Asian cohort.
Methods:
We searched the prospective AF ablation registry to identify patients who underwent AF ablation with 50 W RF energy using the smart touch surround flow catheter (Biosense Webster, Diamond Bar, CA, USA). Visitag™ (Biosense Webster) was used for lesion annotation with predefined settings of catheter stability (3 mm for 5 seconds) and minimum contact force (50% of time >5 g). All patients underwent upper gastrointestinal endoscopy at 1 or 3 days after the ablation.
Results:
A total of 159 patients (mean age: 63±9 years, male: 69%, paroxysmal AF: 45.3%, persistent AF: 27.7%, long-standing persistent AF: 27.0%) were analyzed. Initially, 26 patients underwent pulmonary vein isolation with 50 W for 5 seconds at each point. The remaining 133 patients underwent prolonged RF duration (anterior 10 seconds and posterior 6 seconds). The incidence rates of esophageal erythema/erosion and superficial ulceration were 1.3% for each type of the lesion. Food stasis, a suggestive finding of gastroparesis, was observed in 25 (15.7%) patients. There were no cases of cardiac tamponade, stroke, or death.
Conclusions
In Asian patients, AF ablations using 50 W resulted in very low rates of mild esophageal complications.
4.Esophageal Thermal Injury after Catheter Ablation for Atrial Fibrillation with High-Power (50 Watts) Radiofrequency Energy
Ungjeong DO ; Jun KIM ; Minsoo KIM ; Min Soo CHO ; Gi-Byoung NAM ; Kee-Joon CHOI ; You-Ho KIM
Korean Circulation Journal 2021;51(2):143-153
Background and Objectives:
Data regarding the safety of atrial fibrillation (AF) ablation using high-power (50 W) radiofrequency (RF) energy in Asian populations are limited. This study was conducted to evaluate the incidence and pattern of esophageal injury after highpower AF ablation in an Asian cohort.
Methods:
We searched the prospective AF ablation registry to identify patients who underwent AF ablation with 50 W RF energy using the smart touch surround flow catheter (Biosense Webster, Diamond Bar, CA, USA). Visitag™ (Biosense Webster) was used for lesion annotation with predefined settings of catheter stability (3 mm for 5 seconds) and minimum contact force (50% of time >5 g). All patients underwent upper gastrointestinal endoscopy at 1 or 3 days after the ablation.
Results:
A total of 159 patients (mean age: 63±9 years, male: 69%, paroxysmal AF: 45.3%, persistent AF: 27.7%, long-standing persistent AF: 27.0%) were analyzed. Initially, 26 patients underwent pulmonary vein isolation with 50 W for 5 seconds at each point. The remaining 133 patients underwent prolonged RF duration (anterior 10 seconds and posterior 6 seconds). The incidence rates of esophageal erythema/erosion and superficial ulceration were 1.3% for each type of the lesion. Food stasis, a suggestive finding of gastroparesis, was observed in 25 (15.7%) patients. There were no cases of cardiac tamponade, stroke, or death.
Conclusions
In Asian patients, AF ablations using 50 W resulted in very low rates of mild esophageal complications.
5.Clinical outcomes after pulmonary vein isolation using an automated tagging module in patients with paroxysmal atrial fibrillation
Min Soo CHO ; Jun KIM ; Ungjeong DO ; Minsoo KIM ; Gi‑Byoung NAM ; Kee‑Joon CHOI ; You‑Ho KIM
International Journal of Arrhythmia 2020;21(3):e13-
Background:
An automated tagging module (VISITAG™; Biosense Webster, Irvine, CA) allows objective demonstration of energy delivery. However, the effect of VISITAG™ on clinical outcomes remains unclear. This study evaluated (1) clinical outcome after AF ablation using VISITAG™ and (2) the prevalence of gaps in the ablation line.
Methods:
This retrospective analysis included 157 consecutive patients (mean age, 56.7 years; 73.2% men) with paroxysmal atrial fibrillation who underwent successful PVI between 2013 and 2016. Outcomes after the index procedure were compared between those using the VISITAG™ module (VISITAG group, n = 62) and those not using it (control group, n = 95). The primary outcome was recurrence of AF or atrial tachycardia after a blanking period of 3 months.
Results:
The VISITAG group showed significantly shorter overall procedure time (172.2 ± 37.6 min vs. 286.9 ± 66.7 min, P < 0.001), ablation time (49.8 ± 9.7 min vs. 82.8 ± 28.2 min, P < 0.001), and fluoroscopy time (11.8 ± 5.3 min vs. 34.2 ± 30.1 min, P < 0.001) compared with controls. The 1-year recurrence-free survival rate was not statistically different between the groups (70.8% in the VISITAG group vs. 79.2% in the control group, P = 0.189). Gaps in the VISITAG line were common in the both carina and left side pulmonary veins. Patients without gaps (≥ 5 mm) by the criteria emphasizing catheter stability (> 15 s, < 4 mm range, > 60% force over time, > 6 g contact force) showed higher recurrence-free survival rate compared with those with gaps (borderline statistical significance, 91.7% vs. 66.0%, P = 0.094).
Conclusion
Use of the VISITAG™ module significantly reduced procedure, ablation, and fluoroscopic times with a similar AF/AT recurrence rate compared with the conventional ablation. Clinical implications of minimizing gaps along the ablation line should be evaluated further in the future prospective studies.