1.Diagnostic evaluation of mycobacterium tuberculosis in clinical specimens using polymerase chain reaction.
Cheol Seok CHOI ; Un A KIM ; Kyung Ok LEE
Journal of the Korean Society for Microbiology 1993;28(5):381-389
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymerase Chain Reaction*
2.A Case of Asphyxiating Thoracic Dystrophy with Chronic Renal Failue.
Hyun Jung CHO ; Yoon Kyung LEE ; Dong Un KIM ; Ik Jun LEE
Journal of the Korean Society of Pediatric Nephrology 1998;2(2):196-199
Fine needle aspiration cytology of the salivary lesions was performed on 221 patients at Soonchunhyang University Hospital for 10 years. Of 221 aspirates, 6 aspirates(2.7%) were inadequate, 116 cases(52.5%) were non-neoplastic lesions, 76(34.4%) cases were benign neoplasms and 23 cases(10.4%) were malignant neoplasms. The cytologic diagnoses could be correlated with histologic findings in 58 cases. FNAC correctly discriminated between neoplastic and nonneoplastic lesions in fifty-seven lesions and failed in a case, and overall accuracy, sensitivity, and specificity were 98.3%, 98.0%, and 100.0%. FNAC correctly discriminated malignant neoplasms from benign neoplastic/non- neoplastic lesions in fifty-three cases and failed in five cases, and overall accuracy, sensitivity, and specificity were 91.3%, 72.7%, and 95.7%. Among three false negative cases, two mucoepidermoid carcinomas were misdiagnosed as mucocele and benign neoplasm, and an acinic cell carcinoma were misdiagnosed as Warthin's tumor. Two false positive cases were a Warthin's tumor misdiagnosed as squamous cell carcinoma and a pleomorphic adenoma misinterpretated as suggestive of malignancy. In conclusion, diagnostic accuracy of FNAC of salivary lesions is high, and the possibilities of low grade mucoepidermoid carcinoma and acinic cell carcinoma should be considered on hypocellular smears with mucoid or fluidy background.
Adenoma
3.Expression of Met Protein in Colorectal Carcinoma.
Kyung Un CHOI ; Jin Sook LEE ; Chang Hun LEE ; Mee Young SOL ; Kang Suk SUH
Korean Journal of Pathology 2000;34(7):501-508
Met protein is a transmembrane 190 kD heterodimer with tyrosine kinase activity, encoded by c-Met oncogene. It serves as a high affinity receptor for hepatocyte growth factor (HGF)/scatter factor (SF), a cytokine which stimulates cell proliferation, motility, and invasion. In this study, we immunohistochemically evaluated the expression of Met/hepatocyte growth factor receptor in colorectal cancers. Met protein was expressed in 31 of 72 patients (43.1%). The staining pattern was cytoplasmic in nature, present throughout the tumor, and showed variable intensity from case to case. The relationship between the expression rate and intensity, and age and sex of patients, tumor size (p=0.645), tumor site (p=0.902) and tumor differentiation (p=0.844) was not statistically significant. The expression rate and intensity were significantly correlated with lymphovascular invasion (p=0.001), lymph node metastasis (p=0.010), depth of invasion (0.019), and stage (p=0.023). Cytoplasmic accumulation of Met protein was not associated with enhanced PCNA index of tumor cells (p=0.052). These results suggest that Met protein may play an important role in the invasion and metastasis of colorectal cancer cells.
Cell Proliferation
;
Colorectal Neoplasms*
;
Cytoplasm
;
Hepatocyte Growth Factor
;
Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Oncogenes
;
Proliferating Cell Nuclear Antigen
;
Protein-Tyrosine Kinases
4.MR imaging of spondylolisthesis.
Eui Jong KIM ; Kyung Nam RYU ; Sang Un LEE ; Woo Suk COI ; Sun Wha LEE
Journal of the Korean Radiological Society 1993;29(4):826-832
We evaluated MR imaging of spondylolytic spondylolisthesis degenerative spondylolisthesis and retrolisthesis in 14, 9 and 20 patients respectively. Sagittal and axial spin echo and gradient echo images were obtained with 25-30cm FOV and 5mm/0.5mm thickness/gap by using spine surface coil. Sagittal images showed defects of pars interarticularis just inside of the pedicles of spines in all the cases of spondylolytic spondylolisthesis with relatively variable signal intensity. Displaced vertebrae were commonly observed at L5 (8/14) in spondylolytic spondylolisthesis, at L4 (5/9) in degenerative spondylolisthesis and at variable locations in retrolisthesis. The mean length of displacement of vertebrae in spondylolytic spondylolisthesis was about 7mm and less displacement was onserved in degenerative spondylolisthesis and retrolisthesis. Seven, four and six cases of pseudobulging of disk at displaced level were observed in cases of spondylolytic spondylolisthesis, degenerative spondylolisthesis and retrolisthesis respectively. Seven, five and 14 cases of true disk lesions were onserved in cases of spondylolytic spondylolisthesis, degenertive spondylolisthesis and retrolisthesis respectively. Grade II neural foraminal stenoses (obliteration of one half epidural fat of neural foramen) were commonly (8/14) seen in spondylolytic spondylolisthesis, however the other two types showed less severe neural foraminal stenosis. In conclusion, MR imaging is a highly accurate method for the diagnosis and evaluation of spondylolisthesis and associated lesions of spine and disks.
Constriction, Pathologic
;
Diagnosis
;
Humans
;
Magnetic Resonance Imaging*
;
Methods
;
Spine
;
Spondylolisthesis*
5.Papillary cystic neoplasm of pancreas, report of four cases and review of the literature.
Do Yun SEO ; Seung Un BAIK ; Choong Han LEE ; Kyung Hyun CHOI ; Seung Do LEE
Journal of the Korean Cancer Association 1993;25(5):767-772
No abstract available.
Pancreas*
6.Radiological analysis of parellar ligament length and patellar height after proximal tibial osteotomy.
Dae Kyung BAE ; Sang Un LEE ; Young Ho CHO ; Sang Soon LEE
The Journal of the Korean Orthopaedic Association 1991;26(2):621-626
No abstract available.
Ligaments*
;
Osteotomy*
7.Excision of intrapelvic tumor(myxoma) after sacral amputation and anterior approach.
Sang Un LEE ; Dae Kyung BAE ; Churl Woo JEUN ; Sang Gweon LEE
The Journal of the Korean Orthopaedic Association 1992;27(4):1137-1141
No abstract available.
Amputation*
8.Effects of Depression, Social Support of Tuberculosis Patients on Self-care
Journal of Korean Academy of Community Health Nursing 2022;33(4):456-464
Purpose:
The purpose of this study was by understanding the correlation between the depression, social support and self-care of tuberculosis patients and by identifying the factors that influence the self-care.
Methods:
The study subjects were 119 outpatients who were diagnosed with pulmonary and respiratory tuberculosis at a university hospital in D city. The survey questions measured depression, social support, self-care. Using the SPSS/WIN 23.0 program, the collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlations and multiple regression analysis.
Results:
As a result of correlation analysis, there was a statistically significant negative correlation between self-care and depression (r=-.53, p<.001), and there was a significant positive correlation between self-care and social support (r=.68, p<.001). Factors affecting self-care of the subjects were social support (β=.51, p<.001), depression (β=-.32, p<.001), drug discontinuation experience (β=-.30, p<.001) and drug resistance (β=-.14, p<.001). These factors explained 62% of the variance.
Conclusion
In order to improve the self-care ability of tuberculosis patients, it is necessary to develop education and nursing intervention programs that can lower patients' depression and strengthen social support.
9.CT Evaluation of Sacroiliitis' Differentiation of Infectious Sacroiliitis versus Ankylosing Spondylitis.
Yup YOON ; Sang Un LEE ; Kyung Nam RYU ; Ga Young PARK
Journal of the Korean Radiological Society 1994;30(5):943-946
PURPOSE: To determine the characteristic CT findings of infectious sacroiliitis and ankylosing spondylitis. MATERIAL AND METHOD: We retrospectively reviewd CT findings in 10 patients with infectious sacroiliitis confirmed by culture and clinical follow ups and in 5 patients with ankylosing spondylitis by HLA-B27 typing. Mean ages were 30 years in ankylosing spondylitis and 29 years in infectious sacroiliits. CT scans were obtained with GE 9800 or Toshiba 900-S scanner. We analyzed CT findings in regard to the morphology and the degree of bone erosion, and the adjacent soft tissue change. RESULT: All cases of ankylosing spondylitis had bilateral and asymmetic bone erosion, predominantly in ilium, showing subchondral sclerosis on ilium. Infectious sacroiliitis showed unilateral involvement and soft tissue swelling in 10 cases and abscess in 5 cases. CONCLUSION: We concluded that CT was useful in the differentiation between infectious sacroiliitis and ankylosing spondylitis.
Abscess
;
Follow-Up Studies
;
HLA-B27 Antigen
;
Humans
;
Ilium
;
Retrospective Studies
;
Sacroiliitis*
;
Sclerosis
;
Spondylitis, Ankylosing*
;
Tomography, X-Ray Computed
10.Supraclavicular BCG Lymphadenitis Noted at 21 Months after BCG Vaccination Confirmed by a Molecular Method.
Min Hyun LEE ; Moon Hee CHAE ; Kyoung Un PARK ; Hye Kyung CHO
Korean Journal of Pediatric Infectious Diseases 2014;21(2):139-143
Bacille Calmette-Guerin (BCG) lymphadenitis is the most common complication of BCG vaccination. It commonly occurs in infants aged <6 months involving ipsilateral axillary lymph nodes. We described BCG lymphadenitis in a 22-month-old boy presenting swelling of left supraclavicular lymph node that was confirmed by real-time polymerase chain reaction (PCR) and the multiplex PCR targeting the region of difference (RD).
Humans
;
Infant
;
Lymph Nodes
;
Lymphadenitis*
;
Male
;
Multiplex Polymerase Chain Reaction
;
Mycobacterium bovis*
;
Real-Time Polymerase Chain Reaction
;
Vaccination*