1.Measurement and analysis of phased-array focused ultrasound field of two-foci pattern.
Xiumei HUANG ; Jingfeng BAI ; Ying YU ; Yazhu CHEN
Chinese Journal of Medical Instrumentation 2010;34(3):172-174
This paper introduces the simulation and measurement results of the phased-array focused ultrasound field of two-foci pattern.
Ultrasonic Therapy
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methods
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Ultrasonics
2.Perfluoropentane droplets enhanced HIFU therapeutic effect.
Meili ZHU ; Aili ZHANG ; Yu XIANG ; Jingfeng BAI ; Mario FABIILLI ; Brian FOWLKES
Chinese Journal of Medical Instrumentation 2013;37(3):169-172
A small HIFU system was used to investigate the phase-shift droplet vaporization in vivo and its effect on thermal absorption in tissue-mimicking phantoms. The experiments demonstrated that droplets could be vaporized to bubbles in vivo by the small HIFU system and the volume of bubbles could increase by tens of times. With appropriate droplets concentration, lesion volume produced by HIFU could be increased significantly under the same HIFU parameter.
Fluorocarbons
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Image Enhancement
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Ultrasonic Therapy
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methods
3.A positioning method of ultrasound probe in MR system.
Bo WEI ; Guofeng SHEN ; Sheng CHEN ; Mengyuan ZHU ; Zhiqiang SU ; Yazhu CHEN
Chinese Journal of Medical Instrumentation 2013;37(3):166-177
This paper provides a method of positioning the ultrasound probe in MR system. Machining 6 slots or cylinder perpendicular to the ultrasound probe surface on the edge of ultrasound probe as markers, 12 central cylinder ends are chosen as positioning points. By calculating these positioning points' coordinates in MR's coordinate system, the coordinate transformation between the ultrasound and MR coordinate system can be computed. Furthermore, by taking advantage of redundant information, calculating errors can be reduced and the precision can be improved.
Magnetic Resonance Imaging
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Ultrasonic Therapy
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methods
4.High-intensity focused ultrasound transducer.
Journal of Biomedical Engineering 2009;26(3):667-670
High-intensity focused ultrasound (HIFU) has been used to precisely ablate a targeted area within the body without harming the overlying tissues. In recent years, HIFU, as a noninvasive, effective and feasible modality, has been used for cancer therapy. The development of HIFU transducer is the key technology of HIFU. This paper shows the acoustic lens transducer, spherical auto-focused transducer, pluralistic auto-focused transducer and the electronic phased array transducer in HIFU treatment, and the performance of each of the four HIFU transducers was evaluated.
Equipment Design
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Humans
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Neoplasms
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therapy
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Transducers
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Ultrasonic Therapy
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instrumentation
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methods
5.The research of intensity focused ultrasound on the treatment of allergic rhinitis.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2012;26(14):670-672
Allergic rhinitis is a common disease in otorhinolaryngology, there are lots of physiotherapies now, the overview of the research of intensity focused ultrasound on the treatment of allergic rhinitis was mainly reviewed.
Humans
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Rhinitis, Allergic
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Rhinitis, Allergic, Perennial
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therapy
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Ultrasonic Therapy
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methods
6.Low-intensity pulsed ultrasound stimulates proliferation of stem/progenitor cells: what we need to know to translate basic science research into clinical applications.
Yan TAN ; Yang GUO ; Amanda B REED-MALDONADO ; Zheng LI ; Guiting LIN ; Shu-Jie XIA ; Tom F LUE
Asian Journal of Andrology 2021;23(6):602-610
Low-intensity pulsed ultrasound (LIPUS) is a promising therapy that has been increasingly explored in basic research and clinical applications. LIPUS is an appealing therapeutic option as it is a noninvasive treatment that has many advantages, including no risk of infection or tissue damage and no known adverse reactions. LIPUS has been shown to have many benefits including promotion of tissue healing, angiogenesis, and tissue regeneration; inhibition of inflammation and pain relief; and stimulation of cell proliferation and differentiation. The biophysical mechanisms of LIPUS remain unclear and the studies are ongoing. In recent years, more and more research has focused on the relationship between LIPUS and stem/progenitor cells. A comprehensive search of the PubMed and Embase databases to July 2020 was performed. LIPUS has many effects on stem cells. Studies show that LIPUS can stimulate stem cells in vitro; promote stem cell proliferation, differentiation, and migration; maintain stem cell activity; alleviate the problems of insufficient seed cell source, differentiation, and maturation; and circumvent the low efficiency of stem cell transplantation. The mechanisms involved in the effects of LIPUS are not fully understood, but the effects demonstrated in studies thus far have been favorable. Much additional research is needed before LIPUS can progress from basic science research to large-scale clinical dissemination and application.
Cell Proliferation
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Humans
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Signal Transduction
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Stem Cells/radiation effects*
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Ultrasonic Therapy/methods*
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Ultrasonic Waves
7.Framework design of MRI guided phased HIFU system and software development.
Ruifeng MA ; Guofeng SHEN ; Shan QIAO ; Bo WEI ; Sheng CHEN ; Yazhu CHEN
Chinese Journal of Medical Instrumentation 2013;37(2):96-99
This paper introduced a new structure of MRI guided P-HIFU therapy system and software implementation based on the current P-HIFU system and interface provided by MRI vendor. The tests showed that the system's software can achieve the appropriate form of treatment need.
Magnetic Resonance Imaging
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Software Design
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Ultrasonic Therapy
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methods
9.Development of external therapeutical ultrasound systems (ETUS) for acute myocardial infarction.
Chinese Journal of Medical Instrumentation 2005;29(4):247-259
This paper introduces the principle and structure of the ETUS system for acute myocardial infarction. This system is an assistant treatment tool with ultrasound waves acting from the external on the heart, speeding thrombolytic drug's permeation into the thrombi for a good curative effect.
Equipment Design
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Myocardial Infarction
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drug therapy
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therapy
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Thrombolytic Therapy
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methods
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Ultrasonic Therapy
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instrumentation
10.High-Intensity Focused Ultrasound Therapy: an Overview for Radiologists.
Young sun KIM ; Hyunchul RHIM ; Min Joo CHOI ; Hyo Keun LIM ; Dongil CHOI
Korean Journal of Radiology 2008;9(4):291-302
High-intensity focused ultrasound therapy is a novel, emerging, therapeutic modality that uses ultrasound waves, propagated through tissue media, as carriers of energy. This completely non-invasive technology has great potential for tumor ablation as well as hemostasis, thrombolysis and targeted drug/gene delivery. However, the application of this technology still has many drawbacks. It is expected that current obstacles to implementation will be resolved in the near future. In this review, we provide an overview of high-intensity focused ultrasound therapy from the basic physics to recent clinical studies with an interventional radiologist's perspective for the purpose of improving the general understanding of this cutting-edge technology as well as speculating on future developments.
Drug Delivery Systems
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Gene Targeting
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Hemostatic Techniques
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Humans
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Thrombolytic Therapy/methods
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*Ultrasonic Therapy/methods