This paper introduces the simulation and measurement results of the phased-array focused ultrasound field of two-foci pattern.
Ultrasonic Therapy ; methods ; Ultrasonics

The Harmonic Scalpel made by Ultracision is a system for endoscopic cutting. The energy source is vibration. The power box is attached to a forceps or blade, and the vibrational frequency of the blade approaches 55,500 cycles/second. This causes a knife-like action of the blade through tissue, with enough heating to create coagulation of small vessels. When this vibration energy is applied to the forceps configuration, coagulation occurs. By rotating the bottom blade of the forceps, the instrument becomes like a pair of scissors, and the tissue can divide. The Harmonic Scalpel allows the operator to cut using a tactile tissue. No smoke is created, only microaromized water droplets which are rapidly absorbed by the peritoneak surface. The instrument is extremely safe in that only tissue which is touched is cut; the energy source cannot travel through air, such as can happen with electrosurgery and laser surgery.
Animal ; Electrocoagulation ; Endoscopy* ; Human ; Laparoscopy ; Ultrasonic Therapy*

A small HIFU system was used to investigate the phase-shift droplet vaporization in vivo and its effect on thermal absorption in tissue-mimicking phantoms. The experiments demonstrated that droplets could be vaporized to bubbles in vivo by the small HIFU system and the volume of bubbles could increase by tens of times. With appropriate droplets concentration, lesion volume produced by HIFU could be increased significantly under the same HIFU parameter.
Fluorocarbons ; Image Enhancement ; Ultrasonic Therapy ; methods

This paper provides a method of positioning the ultrasound probe in MR system. Machining 6 slots or cylinder perpendicular to the ultrasound probe surface on the edge of ultrasound probe as markers, 12 central cylinder ends are chosen as positioning points. By calculating these positioning points' coordinates in MR's coordinate system, the coordinate transformation between the ultrasound and MR coordinate system can be computed. Furthermore, by taking advantage of redundant information, calculating errors can be reduced and the precision can be improved.
Magnetic Resonance Imaging ; Ultrasonic Therapy ; methods

Low-intensity pulsed ultrasound (LIPUS) is a promising therapy that has been increasingly explored in basic research and clinical applications. LIPUS is an appealing therapeutic option as it is a noninvasive treatment that has many advantages, including no risk of infection or tissue damage and no known adverse reactions. LIPUS has been shown to have many benefits including promotion of tissue healing, angiogenesis, and tissue regeneration; inhibition of inflammation and pain relief; and stimulation of cell proliferation and differentiation. The biophysical mechanisms of LIPUS remain unclear and the studies are ongoing. In recent years, more and more research has focused on the relationship between LIPUS and stem/progenitor cells. A comprehensive search of the PubMed and Embase databases to July 2020 was performed. LIPUS has many effects on stem cells. Studies show that LIPUS can stimulate stem cells in vitro; promote stem cell proliferation, differentiation, and migration; maintain stem cell activity; alleviate the problems of insufficient seed cell source, differentiation, and maturation; and circumvent the low efficiency of stem cell transplantation. The mechanisms involved in the effects of LIPUS are not fully understood, but the effects demonstrated in studies thus far have been favorable. Much additional research is needed before LIPUS can progress from basic science research to large-scale clinical dissemination and application.
Cell Proliferation ; Humans ; Signal Transduction ; Stem Cells/radiation effects* ; Ultrasonic Therapy/methods* ; Ultrasonic Waves

Ultrasound therapy is a new type of therapy technology, there are hyperthermia and high intensity focused ultrasound surgery (HIFUS). Compared with a single frequency system, mutiple frequency system has an additional function to combine power patterns of different frequencies. This function increases the availability of power patterns to treat tumors of various shapes and depths. Therefore, we have in this article proposed a system with the ability to drive ultrasonic phased arrays of multiple resonant frequencies for ultrasound hyperthermia and HIFUS. The results show that this system is able to (1) drive multi-element applicators or phased arrays of a single resonant frequency through the multichannel power amplifiers, (2) concurrently drive transducer with different resonant frequencies, (3) adjust the relative phase and output power of each channel for the scanning ultrasonic focus, and (4) operate each channel with good output stability.
Equipment Design ; Humans ; Neoplasms ; therapy ; Transducers ; Ultrasonic Therapy ; instrumentation

High-intensity focused ultrasound (HIFU) has been used to precisely ablate a targeted area within the body without harming the overlying tissues. In recent years, HIFU, as a noninvasive, effective and feasible modality, has been used for cancer therapy. The development of HIFU transducer is the key technology of HIFU. This paper shows the acoustic lens transducer, spherical auto-focused transducer, pluralistic auto-focused transducer and the electronic phased array transducer in HIFU treatment, and the performance of each of the four HIFU transducers was evaluated.
Equipment Design ; Humans ; Neoplasms ; therapy ; Transducers ; Ultrasonic Therapy ; instrumentation ; methods

Allergic rhinitis is a common disease in otorhinolaryngology, there are lots of physiotherapies now, the overview of the research of intensity focused ultrasound on the treatment of allergic rhinitis was mainly reviewed.
Humans ; Rhinitis, Allergic ; Rhinitis, Allergic, Perennial ; therapy ; Ultrasonic Therapy ; methods

OBJECTIVETo investigate the effect of low-frequency ultrasound in promoting milk secretion in rats during lactation.

METHODSTwenty-four lactating SD rats feeding 10 suckling rats each were randomly allocated into 3 groups, namely the control group (with sham irradiation), 5 min group (with ultrasonic irradiation of the breast for 5 min daily), and 10 min group (irradiation for 10 min daily). The mammary glands of the rats were consistently irradiated by low-frequency ultrasound (40 kHz, 0.26 W/cm(2)) for 7 days since the 2nd day after delivery. The milk yield, average body weight gain of the offspring, mammary gland index, serum prolactin (PRL) and breast histology were examined.

RESULTSThe milk yield, body weight gain of offspring, mammary gland index and serum PRL concentration in 10 min group were significantly greater than those in the control group and 5 min group (P<0.05). Compared with the other two groups, the 10 min group showed significantly increased acinar gland expansion and acinar number.

CONCLUSIONLow-frequency ultrasound can promote milk secretion in lactating rats, suggesting its potential as a new approach of physical therapy for promoting milk secretion.

This paper introduced a new structure of MRI guided P-HIFU therapy system and software implementation based on the current P-HIFU system and interface provided by MRI vendor. The tests showed that the system's software can achieve the appropriate form of treatment need.
Magnetic Resonance Imaging ; Software Design ; Ultrasonic Therapy ; methods