1.Severe Neurotoxic Envenoming and Cardiac Complications after the Bite of a ‘Sind Krait’ (Bungarus cf. sindanus) in Maharashtra, India
Lalitha V. Pillai ; Dhananjay Ambike ; Saifuddin Husainy ; Anil Khaire ; Ashok Captain ; Ulrich Kuch
Tropical Medicine and Health 2012;40(3):103-108
We report a case of severe envenoming with unusual complications and two anecdotal cases of fatalities following proven 17-scale-row ‘Sind krait’ (Bungarus cf. sindanus) bites on people sleeping in temporary huts at construction sites in Pune District, Maharashtra, India. A 25-yr-old male developed progressive neuromuscular paralysis, abdominal pain and autonomic disturbances complicated by four prolonged episodes of pulseless ventricular tachycardia requiring defibrillation, and followed by pulmonary edema secondary to impaired left ventricular systolic function and hyperfusion. There was no response to antivenom; mechanical ventilation was required for six days. Only one other case of fatal envenoming likely caused by this species had been reported previously in India. The distribution of B. sindanus sensu lato from eastern Afghanistan to India overlaps with that of the superficially very similar common krait (Bungarus caeruleus). Thus, B. cf. sindanus envenoming may be common but routinely overlooked or misdiagnosed.
2. Modifiable determinants of attitude towards dengue vaccination among healthy inhabitants of Aceh, Indonesia: Findings from a community-based survey
Harapan HARAPAN ; Arsil RADIANSYAH ; Pradiba ANGRAINI ; Riny FASLI ; Salwiyadi SALWIYADI ; Reza Akbar BASTIAN ; Ade OKTIVIYARI ; Imaduddin AKMAL ; Muhammad IQBALAMIN ; Jamalul ADIL ; Fenni HENRIZAL ; Darmayanti DARMAYANTI ; Rovy PRATAMA ; Jhony Karunia FAJAR ; Harapan HARAPAN ; Harapan HARAPAN ; Samsul ANWAR ; Aslam BUSTAMAN ; Abdul Malik SETIAWAN ; Mandira Lamichhane DHIMAL ; Ulrich KUCH ; David Alexander GRONEBERG ; Meghnath DHIMAL ; Ruth MUELLER ; R. Tedjo SASMONO ; Meghnath DHIMAL
Asian Pacific Journal of Tropical Medicine 2016;9(11):1115-1122
Objective To explore and understand the attitude towards dengue vaccination and its modifiable determinants among inhabitants of Aceh (northern Sumatra Island, Indonesia), the region that was most severely affected by the earthquake and tsunami of 26 December 2004. Methods A community-based, cross-sectional study was conducted among 535 healthy inhabitants in nine regencies (Kabupaten or Kotamadya) of Aceh that were selected randomly from November 2014 to March 2015. A set of validated, pre-tested, structured questionnaires was used to guide the interviews. The questionnaires covered a range of explanatory variables and one outcome variable (attitude to dengue vaccination). Multi-step logistic regression analysis and Spearman's rank correlation were used to test the role of explanatory variables for the outcome variable. Results More than 70% of the participants had a poor attitude towards dengue vaccination. Modifiable determinants associated with poor attitude to dengue vaccination were low education level, working as farmers and traditional market traders, low socioeconomic status and poor knowledge, attitude and practice regarding dengue fever (P < 0.05). The KAP domain scores were correlated strongly with attitude to dengue vaccination, rs = 0.25, rs = 0.67 and rs = 0.20, respectively (P < 0.001). Multivariate analysis found that independent predictors associated with attitude towards dengue vaccination among study participants were only sex and attitude towards dengue fever (P < 0.001). Conclusions This study reveals that low KAP regarding dengue fever, low education level and low socioeconomic status are associated with a poor attitude towards dengue vaccination. Therefore, inhabitants of suburbs who are working as farmers or traditional market traders with low socioeconomic status are the most appropriate target group for a dengue vaccine introduction program.