We report s case of angiokeratoma of the vulva occuring in a 36-year-old woman. Numerous grayish dark purple papulovesicular lesions, ranging from 0.2 to 2.0mm in size, were observed on the right labium majus. All lesions were excised under local snesthesia after the diagnosis of angio keratoma was made histopathologically. No new lesions appeared during the follow-up period of one year.
Adult ; Angiokeratoma* ; Diagnosis ; Female ; Follow-Up Studies ; Humans ; Keratosis ; Research Report ; Vulva*

PURPOSE: Hepatitis B virus infection is prevalent in Korea. Active immunization of Hepatitis B has been proceeded extensively for the last decade. This study was performed to estimate the negative rate of anti-HBs after immunization and to evaluate the effect of revaccination among Korean children between 1995 and 1997, as well as to determine a proper revaccination schedule. METHODS: Anti-HBs was measured with enzyme immunoassay. Hepatitis B revaccination was performed on nonresponders, those who were previously vaccinated and whose anti-HBs titers were under 10mIU/mL. Group A was revaccinated one dose of the same amount of the previous vaccine. Group B was given three doses of the same amount of the vaccine. Group C was given one double dose of the vaccine. The seroconversion rate and geometrical mean titer were measured one month later. RESULTS: Negative anti-HBs rate was 14.5% in children who had been vaccinated. The seroconversion rate was high in all revaccination groups(86.7-94.7%). Three doses of revaccination had no significant difference from one dose of revaccination. There was no positive effect of double dose of revaccination in comparison with the usual dose. CONCLUSION: In our study, one dose of hepatitis B vaccine is as effective as three doses or double dose of hepatitis B vaccine for the nonresponsive children. We recommend administering one dose of hepatitis B vaccine to those children whose three anti-HBs titer is under 10mIU/mL and examining of the anti-HBs titer one month later after revaccination.
Appointments and Schedules ; Child* ; Hepatitis B Vaccines ; Hepatitis B virus ; Hepatitis B* ; Hepatitis* ; Humans ; Immunization ; Immunization, Secondary* ; Immunoenzyme Techniques ; Korea ; Vaccination

We report two cases of hyperkeratosis of the nipple and areola which occurred in 22-year-old woman and 13-year-old girl. The former was suffered from mild pruritic, verrucous thickening and brownish discoloration of both nipples and areolae for 5 years. The latter had asymptomatic, verrucous thickening and dark brownish hyper- pigmentation of the right nipple and areola for 3 years. Both showed mild to marked hyperkeratosis and papillomatosis with increased pigmentation in the basal cell layer histopathologically. In both cases, the lesions were not responsive to the topical medications including steroids and keratolytic agents. Therefore we recommended surgical excision because the patients are greatly disturbed by the appearance of the lesions.
Adolescent ; Female ; Humans ; Keratolytic Agents ; Nipples* ; Papilloma ; Pigmentation ; Steroids ; Young Adult

PURPOSE: This study was performed to characterize the epidemiologic and clinical features of acute adenoviral lower respiratory tract infections. METHODS: Culture and indirect immunofluorescence for adenovirus was done with nasopharyngeal aspirates from patients with acute lower respiratory tract infections from April to September, 1996. Cultured virus was serotyped for type 3, 4, and 7a by neutralization test, and medical records were reviewed. RESULTS: Adenovirus was isolated from 29 of 187 (15.5%) patients. Monthly distribution from May to September, 1996 was 4, 17, 7, 0, and 1 case, respectively. Seventeen out of 18 cases serotyped (94.4%) were type 7. Male to female ratio was 21:8 and ranged in age from 1 month to 8 years with a mean of 22.6 +/- 22.5 months. Clinical diagnosis was pneumonia in 18, tracheobronchitis in 6, and bronchiolitis in 4 cases. The main clinical features were cough (100%), sputum (100%), fever (89%), pharyngeal injection (85%), increased ESR (76%) and CRP (64%), and leukocytosis (59%). Radiologic findings of chest, included consolidation (40.7%), parahilar peribronchial infiltration (22.2 %), pleural effusion (7.4%), and hyperaeration (3.7%). The mean duration of admission was 8.9 +/- 5.1 days and all the patients showed favorable clinical outcome without acute respiratory distress syndrome. CONCLUSION: There was a respiratory epidemic by adenovirus between May and July, 1996, and 17 out of 18 cases serotyped was type 7. All of the 29 patients with acute adenoviral lower respiratory tract infections improved without significant complication.
Adenoviridae* ; Bronchiolitis ; Child* ; Cough ; Diagnosis ; Female ; Fever ; Fluorescent Antibody Technique, Indirect ; Humans ; Leukocytosis ; Male ; Medical Records ; Neutralization Tests ; Pleural Effusion ; Pneumonia ; Respiratory Distress Syndrome, Adult ; Respiratory System* ; Respiratory Tract Infections* ; Sputum ; Thorax

PURPOSE: This study was performed to characterize the epidemiologic and clinical features of acute adenoviral lower respiratory tract infections. METHODS: Culture and indirect immunofluorescence for adenovirus was done with nasopharyngeal aspirates from patients with acute lower respiratory tract infections from April to September, 1996. Cultured virus was serotyped for type 3, 4, and 7a by neutralization test, and medical records were reviewed. RESULTS: Adenovirus was isolated from 29 of 187 (15.5%) patients. Monthly distribution from May to September, 1996 was 4, 17, 7, 0, and 1 case, respectively. Seventeen out of 18 cases serotyped (94.4%) were type 7. Male to female ratio was 21:8 and ranged in age from 1 month to 8 years with a mean of 22.6 +/- 22.5 months. Clinical diagnosis was pneumonia in 18, tracheobronchitis in 6, and bronchiolitis in 4 cases. The main clinical features were cough (100%), sputum (100%), fever (89%), pharyngeal injection (85%), increased ESR (76%) and CRP (64%), and leukocytosis (59%). Radiologic findings of chest, included consolidation (40.7%), parahilar peribronchial infiltration (22.2 %), pleural effusion (7.4%), and hyperaeration (3.7%). The mean duration of admission was 8.9 +/- 5.1 days and all the patients showed favorable clinical outcome without acute respiratory distress syndrome. CONCLUSION: There was a respiratory epidemic by adenovirus between May and July, 1996, and 17 out of 18 cases serotyped was type 7. All of the 29 patients with acute adenoviral lower respiratory tract infections improved without significant complication.
Adenoviridae* ; Bronchiolitis ; Child* ; Cough ; Diagnosis ; Female ; Fever ; Fluorescent Antibody Technique, Indirect ; Humans ; Leukocytosis ; Male ; Medical Records ; Neutralization Tests ; Pleural Effusion ; Pneumonia ; Respiratory Distress Syndrome, Adult ; Respiratory System* ; Respiratory Tract Infections* ; Sputum ; Thorax

No abstract available.

The aim of this study is to determine whether full-mouth disinfection therapy(FMT) in our clinical setting would show better improvement of clinical parameters than partial mouth disinfection therapy(PMT) in chronic periodontitis and aggressive periodontitis patients. Among 12 patients, 6 were treated FMT and other 6 were treated PMT. Clinical parameters were calculated 3 months and 6 months after initial therapy. 1. There were no statistically significant differences between FMT and PMT in the reduction rate of bleeding on probing after 3 months, 6 months 2. Initial probing depth was 4-6mm, the mean probing depth after 3 months was 2.2mm vs 2.5mm(FMT vs PMT), after 6 months was 2.4mm vs 2.8mm. This was significantly lower in the FMT groups. 3. Initial probing depth was > or = 7mm, the reduction rate of mean probing depth during first 3 months was 4.8mm vs 4.1mm(FMT vs PMT), and 3 to 6 months was 0.5mm vs 0.3mm. This was significantly larger in the FMT groups. 4. Initial probing depth was 4-6mm, the mean clinical attachment level after 3 months was 2.3mm vs 2.7mm(FMT vs PMT), after 6 months was 2.7mm vs 3.0mm. This was significantly lower in the FMT groups. 5. Initial probing depth was > or = 7mm, the reduction rate of mean probing depth during first 3 months was 4.0mm vs 3.0mm(FMT vs PMT), and 3 to 6 months was 0mm vs -0.1mm. This was significantly larger in the FMT groups. Although the results provided us with succeccful clinical improvement in aggressive periodontitis, further research is needed to prove its additional benefit in the treatment of chronic periodontitis

No abstract available.

The aim of this study is to determine whether full-mouth disinfection therapy(FMT) in our clinical setting would show better improvement of clinical parameters than partial mouth disinfection therapy(PMT) in chronic periodontitis and aggressive periodontitis patients. Among 12 patients, 6 were treated FMT and other 6 were treated PMT. Clinical parameters were calculated 3 months and 6 months after initial therapy. 1. There were no statistically significant differences between FMT and PMT in the reduction rate of bleeding on probing after 3 months, 6 months 2. Initial probing depth was 4-6mm, the mean probing depth after 3 months was 2.2mm vs 2.5mm(FMT vs PMT), after 6 months was 2.4mm vs 2.8mm. This was significantly lower in the FMT groups. 3. Initial probing depth was > or = 7mm, the reduction rate of mean probing depth during first 3 months was 4.8mm vs 4.1mm(FMT vs PMT), and 3 to 6 months was 0.5mm vs 0.3mm. This was significantly larger in the FMT groups. 4. Initial probing depth was 4-6mm, the mean clinical attachment level after 3 months was 2.3mm vs 2.7mm(FMT vs PMT), after 6 months was 2.7mm vs 3.0mm. This was significantly lower in the FMT groups. 5. Initial probing depth was > or = 7mm, the reduction rate of mean probing depth during first 3 months was 4.0mm vs 3.0mm(FMT vs PMT), and 3 to 6 months was 0mm vs -0.1mm. This was significantly larger in the FMT groups. Although the results provided us with succeccful clinical improvement in aggressive periodontitis, further research is needed to prove its additional benefit in the treatment of chronic periodontitis

Alveolar ridge defects may limit or restrict placement of implants. The purpose of this study was to evaluate clinical and histopathologic results which occur following guided bone regeneration using platelet-rich plasma, bovine bone powder and e-PTFE membrane in the localized alveolar bone defects. Ten patients who required guided bone regeneration in implant placemnet, were slelected. Alveolar crest height and width were measured at baseline and, afer 2nd surgery 5 months later At 5 months , we obtained histopathological results as follows: 1. Alveolar crest height was an average of 8.20+/-3.74 mm preoperatively and decreased to an average of 7.40 +/-1.84 mm postoperatively. There was no significant difference. 2. Alveolar crest width was an average of 4.25+/-2.03 mm preoperatively and significantly increased to an average of 7.20+/-2.44 mm postoperatively (P<0.01) 3. The change of Alveolar crest height and width were 0.80+/-1.40 mm, 2.95+/-1.09 mm 4. Histopathological evaluations revealed new bone formation with graft material and laminated bone containing the presence of osteocyte-like cell In conclusion, guided bone regeneration using platelet-rich plasma, bovine bone powder and e-PTFE membrane would provide a viable therapeutic alternative for implant placement in the localized alveolar defect or implant failure
Alveolar Process ; Bone Regeneration ; Humans ; Membranes ; Osteogenesis ; Platelet-Rich Plasma* ; Transplants*