1.Evaluation of some changes in liver function in patients with alcohol use disorder
Udmaral B ; Byambajargal D ; Pagmadulam B ; Oyundelger M ; Zoljargal S ; Oyunchimeg D ; Erdenebat N
Diagnosis 2025;112(1):75-79
Background:
To evaluate changes in liver function in patients with alcohol use disorder and propose preventive measures.
Methods:
In this study, 118 people were examined between January 2024 to December 2024. Results were analyzed SPSS.
Result:
The mean subject age was 48.6± 10.3 years, male: female ratio was 5:1. Mean arterial pressure was 104±12.8 mmHg, ALT 86.7 ± 93.8 (U/L), AST 89.3±82.8 (U/L), GGT 213.8±252.3 (U/L). A statistically
significant correlation was found between AST and ALT levels (R² = 0.562). However, no significant correlation was observed between body mass index (BMI) and blood glucose levels (R² = 0.002). The AST/ALT ratio was also statistically significant (p = 0.0001).
Conclusion
Excessive alcohol consumption increases the levels of liver enzymes AST 89.3 ± 82.8 (U/L), ALT 86.7
± 93.8 (U/L), and GGT 213.8 ± 252.3 (U/L), leading to increased liver cell damage. Therefore, it is necessary to reduce alcohol consumption and implement preventive measures.