1.Effect of intraurethral irrigation with honeysuckle water-decoction on formation of bacterial biofilm on the surface of catheter
Bodong Lü ; Tingting TAO ; Shigeng ZHANG ; Xiaojun HUANG ; Le QIAN ; Yanfeng MA ; Zheng ZHU ; Tuzhen XU
Chinese Journal of Clinical Infectious Diseases 2008;1(5):274-276
Objective To investigate the effect of intraurethral irrigation with honeysuckle water-decoction on formation of bacterial biofilm on the surface of the catheter. Methods Eighty male patients,who had no history of catheterization and no urinary infection with negative results of urine bacterial culture,were enrolled in the study. All patients were randomly divided into 4 groups with 20 cases in each: group A (patients underwent intraurethral irrigation with honeysuckle water-decoction); group B (intraurethral irrigation with 25% PVP); group C (intraurethral irrigation with normal saline ) and group D (no intraurethral irrigation). The urethral catheters were removed at the 7th day and the bacterial biofilm on the surface of the catheter was examined by scanning electron microscopy (SEM). Results SEM demonstrated uneven- distributed matrixes coated on the surface of the catheter, and bacteria adhered to the matrixes. The average thickness of biofilm in group A, B, C and D was (17.876 ±11.788)μn, (31.090±15. 006)μm,(33.716±11.927)μm, (67.762±23.588)μm, respectively. The average thickness of biofilm in group A, B, C was significantly thinner than that in group D (P<0.01), and the thickness in group A was thinner than that in group B and C (P<0.01), but there was no significance difference between group B and group C (P>0.01). Conclusions Intraurethral irrigation with honeysuckle water-decoction can effectively reduce the formation of bacterial biofilm on the surface of the catheter.
2.The effects of pelvic floor muscle training on symptom and quality of life in female patients with overactive bladder
Tuzhen XU ; Qiuhua SUN ; Xiao HUANG ; Bodong LYU ; Peng JIANG ; Hongzhou MENG
Chinese Journal of Urology 2014;35(8):591-595
Objective To elavluate the efficacy of pelvic floor muscle training (PFMT) on symptoms and quality of life in the treatment of female overactive bladder (OAB).Methods Ninety-one female patients with OAB completed the prospective study and were divided into 2 groups.The study group had PFMT combined with comprehensive health education and tolterodine (n =46),and the control group had comprehensive health education combined with tolterodine (n =45).OAB symptom score (OABSS),King's health questionnaire (KHQ) and modified Oxford scale (MOS) were evaluated at baseline,2 weeks,1 month and 3 months.The patients were followed up for 6 months.Results The MOS and OABSS score in study group before the treatment were 2.87±0.65 and 7.61 ±2.28,respectively,and in control group they were 2.80±0.55 and 7.44±2.41,respectively.There was no significant difference between the 2 grotps (P> 0.05).There was no significant difference in KHQ domains before the treatment between the 2 groups (P> 0.05).The MOS scores were 3.15±0.63 and 3.57±0.58 after treatment of 1 and 3 months in study group,which were significantly improved compared with the values of 2.89±0.57 and 3.09±0.67 in control group (P<0.05).The OABSS score was 1.13± 1.93 in study group after treatment of 6 months,which was significantly improved compared with the values of 2.47±2.18 in control group (P<0.05).The Incontinence impact,Role Limitations,Physical Limitations,Social Limitations and Symptom Severity in study group improved significantly compared with the values in control group after treatment of 3 months (P<0.05).Domains of KHQ scores were totally significantly improved after treatment of 6 months in study group than in control group(P<0.05).Conclusion Long term PFMT may play an important role in the treatment of OAB,and can also improve the quality of life of the patients.
3.Investigation of the related factors and quality of life in the female patients with primary overactive bladder
Tuzhen XU ; Qiuhua SUN ; Xiao HUANG ; Bodong LYU
Chinese Journal of Modern Nursing 2014;20(16):1899-1903
Objective To investigate the related factors and quality of life in the female patients with primary overactive bladder (OAB) to provide the basis for the chnical treatment.Methods One hundred and seven female patients with primary OAB were surveyed by the questionnaire about the general data and the King' s Health Questionnaire (KHQ),and the correlation was analyzed by the Spearman.Results The occurrence of female patients with primary OAB was related to the age,marital status,mode of delivery,dehvery times,body mass index,with and without chronic diseases (P < 0.05),and was not related to the education,residential area,abortion and diet habits (P > 0.05).The scores of the general health feeling,the severity of voiding problem,the restricted behavior,restricted motion,social limitations,the personal life,emotion,sleep and energy,the coping style of symptoms,and severity of symptom in KHQ were respectively (61.44 ± 14.68),(81.31 ±26.76),(32.54±28.63),(46.73 ±21.27),(27.91 ±23.75),(20.91 ±25.86),(47.90 ± 28.19),(32.40 ± 23.44),(14.49 ± 17.02),and (8.45 ± 2.69).The score of Overactive Bladder Syndrome Score (OABSS) was positively correlated with the severity of voiding problem,restricted motion,social limitations,emotion,the coping style of symptoms and the severity of symptom (r =0.280,0.334,0.288,0.224,0.325,0.458,respectively; P<0.05).Contusions The symptoms of female patients with primary OAB are related to the age,marital status,delivery times,body mass index,with and without chronic diseases,and OAB can affect the patient' s quality of life in different degrees.