1.Occupational hazards and preventive measures for diving - fishermen
Journal of Preventive Medicine 1998;8(2):22-26
A cross-sectional study was carried out with 539 subjects at Khanh Hoa and Binh Thuan provinces. The results: there was 180 occupational accident during the period from 1997 to 1999, with 31 deaths. Almost of them have not been appropriately trained in diving technique and safety measures. They have not enough protection equipment, diving clothes and oxygen-tubes when diving at 20m depth. Training courses on diving safety measures for fishermen were conducted and recommendations for treatments of diving-fishermen diseases were made. These recommendations have been applied in Ham Tan Hospital (Binh Thuan).
Accidents, Occupational
;
prevention & control
2.A study of pathological characteristics and BRAF V600E status in Langerhans cell histiocytosis of Vietnamese children
Thu Dang Anh PHAN ; Bao Gia PHUNG ; Tu Thanh DUONG ; Vu Anh HOANG ; Dat Quoc NGO ; Nguyen Dinh The TRINH ; Tung Thanh TRAN
Journal of Pathology and Translational Medicine 2021;55(2):112-117
Background:
Langerhans cell histiocytosis (LCH) is more common in children than adults and involves many organs. In children, the BRAF V600E mutation is associated with recurrent and high-risk LCH.
Methods:
We collected paraffin blocks of 94 pediatric LCH patients to detect BRAF V600E mutation by sequencing. The relationship between BRAF V600E status and clinicopathological parameters were also critically analyzed.
Results:
BRAF V600E mutation exon 15 was detected in 45 cases (47.9%). Multiple systems LCH showed a significantly higher BRAF V600E mutation rate than a single system (p=.001). No statistical significance was evident for other clinical characteristics such as age, sex, location, risk organs involvement, and CD1a expression.
Conclusions
In Vietnamese LCH children, the proportion of BRAF V600E mutational status was relatively high and related to multiple systems.