Objective]To observe the clinical effect in treating cystic acne with combination of Yu Shi San Gen Tang and minocycline. [Methods] 120 patients with cystic acne were randomly divided into 3 groups,40 cases in treatment group treated with Yu Shi San Gen Tang and minocycline,40 cases in control group1treated with minocycline and 40 cases in the control group 2 treated with Yu Shi San Gen Tang. These patients were observed the effect after continuously treated for 8 weeks. [Results] In treatment group,15 cases were cured,18 were effective,the total effective rate was 82.5%. In control group1,they were respectively 9,13 and 55%. In control group 2,they were respectively 10,14 and 60%,with significant difference between treatment group and control group1,control group2,and no significant difference between control group 1 and control group 2. [Conclusion] The combination of Yu Shi San Gen Tang and minocycline has a significant curative effect on cystic acne.

Objective:To observe the hemorheological change of vitiligo patients both before and after treatment by Vitiligo Granules or Vitiligo Liniment combined with UVA phototherapy, researching the relationship and clinical significance between vitiligo and hemorheology. Methods: Hemorheological detection was made before and after treatment for 30 normal cases and 58 cases of vitiligo. Results: The total effective rate was 74.15%. The indexes levels of hemorheology of treatment group was higher than those of normal group before treatment (P

Objective:To explore the regulation of Recipe Xiaoban No.1 on the expression of p53 in dystrophy of vulva.Methods:Expression of p53 was determined by immunohistochemical technique in skin lesion of prior treatment and posttreatment from 30 cases with chronic vulvar dystrophy,and normal skin from 23 health adults were served as controls.Results: Expression of p53 in various of chronic dystrophy of vulva before treatment was obviously higher than control group(P0.05).Conclusion:Recipe Xiaoban No.1 can obviously improve the clinical symptoms and decrease the expression rate of P53.

[Objective]To summarize Professor YU Tugen's clinical experience in treating oral lichen planus(OLP).[Methods]Through apprenticeship and clinical following up,medical cases data are documented,collated and analyzed.Simultaneously,by combining research on the pathogenesis of OLP from domestic and international sources,the experiences of Professor YU Tugen in treating OLP are summarized and compiled.The etiology,pathogenesis,principles,methods of treatment and daily care approaches for OLP are comprehensively summarized.Additionally,one clinical case is provided for validation.[Results]OLP is a multifaceted condition,regarded by Professor YU Tugen as an intricate interplay of intrinsic and extrinsic factors rooted in the symbiotic relationship between the spleen and stomach.Pathogenic elements such as heat accumulation,Yin deficiency and emotional perturbations are implicated in its etiology.Therapeutic interventions prioritize the clearance of heat and dampness,fortification of the spleen and stomach and consideration of psychosocial factors,with pharmacological strategies tailored to individual presentations.Proactive health promotion strategies,underscored by the precept of disease prevention,are advocated.A clinical vignette was exemplified for favorable treatment outcomes targeting spleen deficiency and damp-heat oral ulcers.[Conclusion]Professor YU Tugen's treatment of OLP emphasizes the priority of clearing heat and eliminating dampness,with a foundational focus on invigorating the spleen.He pays attention to psychological factors,supplementing the approach with methods to nourish Yin,moisten dryness,resolve emotional stagnation and dispel blood stasis.The therapeutic outcomes have been remarkably positive,offering valuable insights for study and reference.