A descritive study on 2606 people (≥15 year old) who suffered from cough and plegm production that lasted over 3 weeks with the symptoms of suspicious tuberculosis at 20 villages in districts of Văn Lâm, Mĩ Hào, Khoái Châu, Ân Thi, Tiên Lữ, Hưng Yên province from Jan 2000 to Dec 2004. The new incidence of tuberculosis AFB (+) in year 2000: 88.70 AFB (+)/100.000 people, it wasn’t steady and 1.29 time higher than the incidence people in the whole country. Males had higher risk by 1.81 times than females. The illiterates had higher risk by 2.11 times than other subjects. The people who contact with transmitted sources had higher risk by 5.47 times than people who had not this history. There is no relation between occupations, age with TB. This proportion is higher than previous year (1989-1997) from 27.62% to 50.34%; higher than in year 2001: 58.62%; year 2002: 38.59%, year 2003:17.48%, year 2004: 35.00%.
Tuberculosis ; Epidemiology

Introduction: Tuberculosis (TB) is a public health problem worldwide including Brunei Darussalam. Osteoarticular involvement is common. The purpose of this study was to review the demographics, clinical features and treatment outcome of patients with osteoarticular tuberculosis (OATB) in Brunei Darussalam. Material and Methods: Patients receiving treatment for OATB between 2003 and 2008 were identified from the National Tuberculosis Coordinating Centre (NTCC) registry. Data was recorded on pre-designed proforma. Results: Twenty-one patients (10 male: 11 female) were identified with a mean age of 49 years (range 19 to 75). Nineteen were Bruneian citizens. The most common presenting symptoms were pain at affected site (n = 15), focal neurological deficit and loss of appetite (n = 7). Two patients gave a positive family history of TB and three had radiological evidence of pulmonary TB. Radiograph of the involved part was positive in nine cases while advanced imaging studies (computed tomography scan and magnetic resonance imaging) were required in 15 instances. The results of positive confirmatory tests were obtained from: smear (n = 10), culture (n = 3) and biopsy (n = 8). In five cases treatment had to be started without any of the confirmatory tests. The spine was the most common site of involvement (n = 12) with five non-spinal and four cases with combined lesions. Surgical intervention was required in six cases. All patients completed the treatment successfully. Conclusions: OATB is not uncommon in Brunei Darussalam and can present diagnostic problems. A high index of suspicion, early confirmation of diagnosis and complete monitored treatment is necessary for successful management of these cases.
Epidemiology ; Tuberculosis, Osteoarticular ; Tuberculosis

Study of 110 pulmonary tuberculosis patients at Hai Phong tuberculosis and lung disease Hospital, the controls was 50 health people from 6/2002 to 2/2003. 36.36% patients have change of disposition; 28.18% patients have obsessional disorder; 4.55% patients which ideology rules over behaviour. 2.73% patients have hallucination of hearing and 1.82% patiens have optical illusion. Depression rate: pulmonary tuberculosis patients was 45.55%, the controls was 14%. Easy depression 32.73%, medium depression 10.91%, heavy depression 0.91%. Anxiety disorder 36.36%
Epidemiology ; Diagnosis ; Tuberculosis, Pulmonary

The study included 444 people (368 men and 76 women) who were 16 years old and more living in Quang Xuong district. The result showed that knowledge on tuberculosis of these subjects was still low. The number of people having appropriate knowledge on tuberculosis was under 29%. The appropriate knowledge rate was lowest in 55 age group (18.5%), and highest in 16 to 35 age group (28.3%). Some factors effect to knowledge on tuberculosis prevention and treatment was educational level and occupation. Correct knowledge rate was highest in people having univesity and college education (80%) and lowest in people having primary education level (7.4%). Correct knowledge rate in officials was 49.2%, workers 23.5%, fammers 20.9% and in unknow occupational subjects was 12%
Tuberculosis ; Knowledge ; Epidemiology

Bias ; Humans ; Mycobacterium tuberculosis ; Tuberculosis ; epidemiology

The awareness on tuberculosis was determined by an interview conducted on 559 subjects with a symptomatic of cough persisting for > 3 weeks (259 male and 300 female subjects of > 15 year old age). Results showed an insufficiency of knowledge, especially in female subjects. Mass media play an effective role in health education but only > 50% of population could access them frequently
Tuberculosis ; Cough ; Disease ; Awareness ; epidemiology

BACKGROUNDMycobacterial interspersed repetitive units-variable number tandem repeat (MIRU-VNTR) and Beijing family typing based on detecting the deletion of RD105 sequence are two common genotyping methods used to study the molecular epidemiologic characteristics of Mycobacterium (M.) tuberculosis. We collected 218 strains of M. tuberculosis between 2004 and 2006 in the Linxia Hui Autonomous Prefecture of Gansu province in Northwest China.

METHODSMIRU-VNTR analysis and Beijing family typing based on detecting the deletion of RD105 sequence were used to type the 218 strains, and their typing power was evaluated to look for practical and efficient genotyping methods suitable for the region.

RESULTSThe MIRU typing yielded 115 distinct genotypes, including 98 unique isolates and 17 different clusters containing 120 isolates (55.05%); the cluster rate was 47.25%. By detecting the deletion of RD105 sequence, 188 of 218 (86.23%) isolates belonged to Beijing family. Combination of Beijing family typing and MIRU typing yielded 118 distinct patterns, including 101 unique isolates and 17 clusters containing 117 isolates (54.13%). The largest cluster contained 58 strains with MIRU genotype of 223325173533 which contained 50 strains belonging to Beijing family and 8 strains belonging to non-Beijing family.

CONCLUSIONSThe Beijing family strains occupied a large proportion and the Beijing family MIRU genotype 223325173533 is a dominant strain in Linxia of Gansu. Combining detecting the deletion of RD105 and MIRU typing together provides a simple, fast, and effective method which is low in cost and might be practical and suitable for M. tuberculosis genotyping in China.

Alleles ; China ; epidemiology ; Genotype ; Molecular Epidemiology ; Multiplex Polymerase Chain Reaction ; Mycobacterium tuberculosis ; genetics ; pathogenicity ; Tuberculosis ; epidemiology

Objective: To analyze the epidemic characteristics and drug resistance of pulmonary tuberculosis among the floating population in Beijing and to provide a scientific basis for formulating strategies for the prevention and control of tuberculosis among the floating population. Methods: Data of tuberculosis patients who were positive for Mycobacterium tuberculosis culture was collected from 16 districts and one municipal institution of tuberculosis control and prevention in Beijing in 2019. The strain samples were tested for drug sensitivity by the proportional method. According to household registration location, patients were divided into the floating population and Beijing registration. SPSS 19.0 software analyzed tuberculosis patients' epidemic characteristics and drug resistance in the floating population. Results: In 2019, there were 1 171 culture-positive tuberculosis patients in Beijing, among the floating population, 593 (50.64%) patients were identified, with a male-to-female sex ratio of 2.2∶1 (409∶184). Compared to patients under household registration as Beijing residents, a higher proportion of young adults aged 20-39 years (65.09%,386/593) were noticed, with 55.65% (330/593) reported from the urban areas and 96.80% (574/593) were reported the first time. The differences were statistically significant (all P<0.05). After completing the drug sensitivity test, 37 cases were with multiple drug-resistant tuberculosis, accounting for 6.24% (37/593). The rates of isoniazid resistance (42.11%,8/19) and multidrug resistance (21.05%,4/19) in floating population patients after retreatment were significantly higher than those in newly treated patients (11.67%, 67/574 and 5.75%, 33/574), and the differences were statistically significant (all P<0.05). Conclusions: Most patients with tuberculosis in the floating population in Beijing in 2019 were young males aged 20-39 years. The reporting areas were urban areas and the newly treated patients mainly. The patients with tuberculosis in the re-treated floating population were more likely to suffer from multidrug and drug resistance, which should be taken as the key population for prevention and control.
Young Adult ; Humans ; Female ; Male ; Beijing/epidemiology* ; Tuberculosis ; Tuberculosis, Pulmonary/epidemiology* ; Tuberculosis, Multidrug-Resistant/epidemiology* ; Drug Resistance

Humans ; Recurrence ; Risk Factors ; Tuberculosis ; epidemiology

Humans ; Incidence ; Risk Factors ; Tuberculosis ; epidemiology