1.Infantile psoas abscess.
Annals of the Academy of Medicine, Singapore 2013;42(8):415-416
Female
;
Humans
;
Infant
;
Psoas Abscess
;
diagnosis
;
drug therapy
;
etiology
;
Tuberculosis
;
complications
;
diagnosis
;
drug therapy
2.Exogenous lipoid pneumonia complicated with mycobacterium infection in a subject with Zenker diverticulum.
Afroditi K BOUTOU ; Ioannis TRIGONIS ; Asterios PIGADAS ; Paraskevi ARGYROPOULOU ; Ioannis STANOPOULOS
Annals of the Academy of Medicine, Singapore 2009;38(2):177-178
Aged, 80 and over
;
Antitubercular Agents
;
therapeutic use
;
Biopsy
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Male
;
Mycobacterium tuberculosis
;
isolation & purification
;
Pneumonia, Lipid
;
diagnosis
;
drug therapy
;
etiology
;
Tomography, X-Ray Computed
;
Tuberculosis, Pulmonary
;
diagnosis
;
drug therapy
;
etiology
;
Zenker Diverticulum
;
complications
;
diagnosis
3.Nododuodenal Fistula Caused by Tuberculosis.
The Korean Journal of Internal Medicine 2011;26(4):477-477
4.Tuberculous paraplegia in pregnancy treated by surgery.
Harwant SINGH ; Jaspal SINGH ; Borhan Tan ABDULLAH ; Alex MATTHEWS
Singapore medical journal 2002;43(5):251-253
Tuberculous paraplegia in pregnancy is reported to be rare. Paraplegia due to tuberculosis has a good prognosis if surgical decompression and stabilisation are done early together with chemotherapy. Vaginal delivery is not contraindicated in pregnancy complicated by paraplegia, but is associated with problems related to the initiation and progression of labour. Performing spinal nursing on an unstable spine with a rapidly enlarging gravid uterus in the third trimester of pregnancy poses a significant challenge. We report successful simultaneous Caesarean section and surgical treatment of a paraplegic spine due to tuberculosis.
Adult
;
Antitubercular Agents
;
therapeutic use
;
Bone Transplantation
;
Cesarean Section
;
Combined Modality Therapy
;
Decompression, Surgical
;
Drainage
;
Female
;
Humans
;
Paraplegia
;
etiology
;
surgery
;
Pregnancy
;
Pregnancy Complications, Infectious
;
diagnosis
;
drug therapy
;
surgery
;
Thoracic Vertebrae
;
Treatment Outcome
;
Tuberculosis, Spinal
;
complications
;
diagnosis
;
drug therapy
;
surgery
5.Clinical Effects of Gemifloxacin on the Delay of Tuberculosis Treatment.
Seo Yun KIM ; Jae Joon YIM ; Jong Sun PARK ; Sung Soo PARK ; Eun Young HEO ; Chang Hoon LEE ; Hee Soon CHUNG ; Deog Kyeom KIM
Journal of Korean Medical Science 2013;28(3):378-382
Although gemifloxacin has low in vitro activity against Mycobacterium tuberculosis, the effect of gemifloxacin on the delay of tuberculosis (TB) treatment has not been validated in a clinical setting. The study group included patients with culture-confirmed pulmonary TB who initially received gemifloxacin for suspected community-acquired pneumonia (CAP). Two control groups contained patients treated with other fluoroquinolones or nonfluoroquinolone antibiotics. Sixteen cases were treated with gemifloxacin for suspected CAP before TB diagnosis. Sixteen and 32 patients were treated with other fluoroquinolones and nonfluoroquinolones, respectively. The median period from the initiation of antibiotics to the administration of anti-TB medication was nine days in the gemifloxacin group, which was significantly different from the other fluoroquinolones group (35 days). The median times for the nonfluoroquinolone group and the gemifloxacin group were not significantly different. There were no significant differences between the gemifloxacin and other fluoroquinolone group in terms of symptomatic and radiographic improvements. However, the frequency of radiographic improvement in the other fluoroquinolones group tended to be higher than in the gemifloxacin group. Gemifloxacin might be the preferred fluoroquinolone for treating CAP, to alleviate any concerns about delaying TB treatment.
Adult
;
Aged
;
Anti-Bacterial Agents/*therapeutic use
;
Case-Control Studies
;
Fluoroquinolones/*therapeutic use
;
Humans
;
Middle Aged
;
Naphthyridines/*therapeutic use
;
Pneumonia/complications/diagnosis
;
Tuberculosis/complications/*drug therapy/radiography
6.Primary mucosal tuberculosis of head and neck region: a clinicopathologic analysis of 47 cases.
Chinese Journal of Pathology 2013;42(10):683-686
OBJECTIVETo study the clinicopathologic features, histologic diagnosis and differential diagnosis of primary mucosal tuberculosis (TB) in the head and neck region.
METHODSForty-seven cases of primary mucosal TB of the head and neck region were studied by hematoxylin-eosin and Ziehl-Neelsen stains. The clinical and pathologic features were analyzed with review of the literature.
RESULTSThe patients included 26 male and 21 female, with mean age 47.1 years (range 14-84 years). There were three sinonasal TB, 19 nasopharyngeal TB, two oropharyngeal TB, 18 laryngeal TB, four middle ear TB, one salivary gland TB and one laryngeal TB complicating laryngeal cancer. The initial symptoms were nasal obstruction, mucopurulent rhinorrhea, epistaxis, snoring, hoarseness, dysphagia, odynophagia, serous otitis, hearing loss, tinnitus, and otalgia. Physical examination result was variable, from an apparently normal mucosa, to an evident mass, or a mucosa with an adenotic or swollen appearance, ulcers, leukoplakic areas, and various combinations thereof. CT and MRI findings included diffuse thickening, a soft-tissue mass, calcification within the mass and bone destruction resembling malignancy. Histologic examination showed granulomas with a central necrotic focus surrounded by epithelioid histiocytes and multinucleated Langhan's giant cells. Acid-fast bacilli were difficult to demonstrate but found in 13/45 cases. Follow-up data were available in 42 patients.
CONCLUSIONSPrimary TB arising in the head and neck mucosa is rare. It may mimic or co-exist with other conditions. The characteristic histopathology is a granuloma with central caseous necrosis and Langhans'giant cells. Identification of acid-fast bacilli and bacteriologic culture confirm the diagnosis of mycobacterial disease.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antitubercular Agents ; therapeutic use ; Carcinoma, Squamous Cell ; complications ; microbiology ; surgery ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Humans ; Laryngeal Neoplasms ; complications ; microbiology ; surgery ; Male ; Middle Aged ; Otorhinolaryngologic Diseases ; diagnostic imaging ; drug therapy ; microbiology ; pathology ; Tomography, X-Ray Computed ; Tuberculin Test ; Tuberculosis ; diagnostic imaging ; drug therapy ; pathology ; Tuberculosis, Laryngeal ; complications ; surgery ; Tuberculosis, Oral ; drug therapy ; pathology ; Young Adult
7.Disseminated Histoplasmosis and Tuberculosis in a Patient with HIV Infection.
Hye Won JEONG ; Jang Wook SOHN ; Min Ja KIM ; Jung Woo CHOI ; Chul Hwan KIM ; Sang Ho CHOI ; Jeeyong KIM ; Yunjung CHO
Yonsei Medical Journal 2007;48(3):531-534
Histoplasmosis is a very rare disease in Korea. Clinical manifestations are very similar to those of tuberculosis. This is the first case report of combined disseminated histoplasmosis and tuberculosis in a patient with HIV infection in Korea. A 42-year-old Korean with Acquired Immunodeficiency Syndrome (AIDS) was diagnosed with tuberculosis. He had lived in Guatemala for the past five years. Upon diagnosis of disseminated tuberculosis with HIV infection, he was treated with anti-tuberculosis medications and anti-retroviral agents. Fever, weakness, hepatosplenomegaly and pancytopenia were persistent despite treatment. The patient's history of living in Guatemala caused us to seek opportunistic infectious organisms other than tuberculosis. Bone marrow aspiration and biopsy were performed and the result revealed numerous intracellular organisms consistent with Histoplasma capsulatum; therefore, the diagnosis of disseminated histoplasmosis was made.
AIDS-Related Opportunistic Infections/microbiology
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Acquired Immunodeficiency Syndrome/complications/pathology
;
Adult
;
Bone Marrow/microbiology/pathology
;
HIV Infections/*complications/drug therapy
;
Histoplasma/isolation & purification
;
Histoplasmosis/complications/*diagnosis/microbiology
;
Humans
;
Male
;
Thorax/microbiology/pathology/radionuclide imaging
;
Tuberculosis/complications/*diagnosis
8.A Case of Acute Appendicitis due to Intestinal Stricture after Intestinal Tuberculosis Treatment.
Sang Bong AHN ; Dong Soo HAN ; Chang Soo EUN ; So Young BANG ; Young chul LEE ; Keum Nam RIM ; Yong Gu LEE ; Tae Yeob KIM
The Korean Journal of Gastroenterology 2007;50(4):277-279
Intestinal hemorrhage, perforation, obstruction, and fistula formation are the common complications associated with intestinal tuberculosis. However, these complications usually occurr in active stage of intestinal tuberculosis. A 45-year-old man was diagnosed as intestinal tuberculosis and received anti-tuberculosis medications for 9 months. After the end of treatment, intestinal lesion was cured. However a deformed appendiceal orifice due to hypertrophic sear resulting in symptomatic appendictis was noted. We report a case of acute appendicitis due to intestinal stricture after the successful treatment of intestinal tuberculosis.
Acute Disease
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Antitubercular Agents/therapeutic use
;
Appendicitis/*diagnosis/etiology/surgery
;
Colonoscopy
;
Diagnosis, Differential
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Humans
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Male
;
Middle Aged
;
Tomography, X-Ray Computed
;
Tuberculosis, Gastrointestinal/complications/*drug therapy
9.A tuberculous midpalmar abscess of the hand due to reactivation of previous pulmonary tuberculosis.
Gavin C W KANG ; Andrew YAM ; Jonathan Y L LEE
Annals of the Academy of Medicine, Singapore 2008;37(11):982-983
Abscess
;
diagnosis
;
etiology
;
therapy
;
Antitubercular Agents
;
therapeutic use
;
DNA, Bacterial
;
analysis
;
Debridement
;
methods
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Male
;
Metacarpus
;
Middle Aged
;
Mycobacterium tuberculosis
;
genetics
;
isolation & purification
;
Tuberculosis, Pulmonary
;
complications
;
drug therapy
;
microbiology
10.A Case of Pseudomembranous Colitis Associated with Rifampicin Therapy in a Patient with Rectal Cancer and Gastrointestinal Tuberculosis.
Yong Jun CHOI ; Hyung Gil KIM ; Yun Ah CHOI ; Woo Chul JOO ; Dong Wook SON ; Chul Hyun KIM ; Yong Woon SHIN ; Young Soo KIM
The Korean Journal of Gastroenterology 2009;53(1):53-56
Pseudomembranous colitis (PMC) is known to be associated with the administration of antibiotics which alter normal gastrointestinal flora and allow overgrowth of Clostridium difficile. Most cases of rifampicin-induced PMC are seen in patients with pulmonary tuberculosis, but not with gastrointestinal tuberculosis. We report a case of PMC associated with rifampicin therapy in a patient with gastrointestinal tuberculosis. A 65-year-old female patient with rectal cancer and gastrointestinal tuberculosis was admitted due to abdominal pain and diarrhea. She was treated with anti-tuberculosis agents containing rifampicin. On colonoscopic examination, mucoid exudates and yellowish plaque lesions were observed. Anti-tuberculosis agents were stopped, and the patient was treated with metronidazole. Symptoms were relieved and did not recur when all the anti-tuberculosis agents except rifampicin were started again. When a patient complains of abdominal pain or diarrhea while taking rifampicin, the physician should consider the possibility of rifampicin-associated PMC.
Aged
;
Antibiotics, Antitubercular/*adverse effects/therapeutic use
;
Enterocolitis, Pseudomembranous/*diagnosis/etiology/pathology
;
Female
;
Humans
;
Rectal Neoplasms/*complications/diagnosis
;
Rifampin/*adverse effects/therapeutic use
;
Sigmoidoscopy
;
Tuberculosis, Gastrointestinal/complications/diagnosis/*drug therapy