1.Preliminary remarks on the use of CT scanner in comparing with pathologic anatomy in diagnosis of tumor of parotis saliva glandula
Journal of Practical Medicine 2004;483(7):17-18
17 patients aged 18-72 years old were treated in Ha Noi Odonto-maxil -facial Institute with the diagnosis of tumor of parotid saliva glandula. Pathologic-amatomical diagnosis using CT scanner was limited for parotid glandula, this did not suggest accurately about cytological cause, only pathological anatomy could play the affirmative role on diagnosis. CT scanning permits to assess precisely the location, the size, the intensity, the frontier and the broading of the tumor. However, this technique could not evaluate the branch duct system of the gland obviously, comprehensively and it requires modern equipments with high cost for the patient.
Tomography, X-Ray Computed
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Anatomy
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Pathology
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Neoplasms
2.Clinical feature of some cases of the mandibullar condylar fracture due to the trauma and treatment
Journal of Vietnamese Medicine 2001;263(9):139-140
A study on 696 patients with the mandibullar condylar fracture due to the trauma in the institute of the odonto stamotology and facio maxilogy during 1992-1996 was carried out to determine the cause, age, gender, position of fracture, clinical features and methods of the treatment. The results found that the early and presise diagnosis gave a good efficacy of the treatment and prevented from complications
Mandibular Condyle
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Mandibular Fractures
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diagnosis
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therapeutics
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Wounds and Injuries
3.Alkaloids with Acetylcholinesterase Inhibitory Activities from Crinum latifolium L.
Vu Thi TRANG ; Pham Van CONG ; Nguyen Van DAN ; Nguyen Thi Thu HIEN ; Do Thanh TUAN ; Le Tuan ANH ; Hoang Dac THANG ; Ngo Viet DUC ; Hoang Le Tuan ANH
Natural Product Sciences 2024;30(4):304-308
A new crinane-type alkaloid, 6-epihydroxypowelline (1), together with six known alkaloids, lycorine (2), 2-O-acetyllycorine (3), deacetylbowdensine (4), 1-epideacetylbowdensine (5), 8-demethyl-3-oxomaritidine (6), and (-)-marithamine (7) were isolated from the whole parts of the Crinum latifolium L. in Vietnam. The structure identification of all compounds was determined by 1D, 2D-NMR as well as HR-ESI-MS spectroscopic techniques. The absolute configuration of these compounds was established by the ECD data. In addition, in vitro inhibition of acetylcholinesterase (AChE) activities was assessed for all isolated alkaloids. All alkaloids had AChE inhibitory effects, with IC50 values ranging from 32.65 ± 2.72 to 212.76 ± 8.30 µM and compound 3 displayed the strongest inhibition of AChE, with IC50 values of 32.65 ± 2.72 µM (in comparison to the reference drug, galanthamine, which had an IC50 of 2.40 ± 0.45 µM).
4.Alkaloids with Acetylcholinesterase Inhibitory Activities from Crinum latifolium L.
Vu Thi TRANG ; Pham Van CONG ; Nguyen Van DAN ; Nguyen Thi Thu HIEN ; Do Thanh TUAN ; Le Tuan ANH ; Hoang Dac THANG ; Ngo Viet DUC ; Hoang Le Tuan ANH
Natural Product Sciences 2024;30(4):304-308
A new crinane-type alkaloid, 6-epihydroxypowelline (1), together with six known alkaloids, lycorine (2), 2-O-acetyllycorine (3), deacetylbowdensine (4), 1-epideacetylbowdensine (5), 8-demethyl-3-oxomaritidine (6), and (-)-marithamine (7) were isolated from the whole parts of the Crinum latifolium L. in Vietnam. The structure identification of all compounds was determined by 1D, 2D-NMR as well as HR-ESI-MS spectroscopic techniques. The absolute configuration of these compounds was established by the ECD data. In addition, in vitro inhibition of acetylcholinesterase (AChE) activities was assessed for all isolated alkaloids. All alkaloids had AChE inhibitory effects, with IC50 values ranging from 32.65 ± 2.72 to 212.76 ± 8.30 µM and compound 3 displayed the strongest inhibition of AChE, with IC50 values of 32.65 ± 2.72 µM (in comparison to the reference drug, galanthamine, which had an IC50 of 2.40 ± 0.45 µM).
5.Alkaloids with Acetylcholinesterase Inhibitory Activities from Crinum latifolium L.
Vu Thi TRANG ; Pham Van CONG ; Nguyen Van DAN ; Nguyen Thi Thu HIEN ; Do Thanh TUAN ; Le Tuan ANH ; Hoang Dac THANG ; Ngo Viet DUC ; Hoang Le Tuan ANH
Natural Product Sciences 2024;30(4):304-308
A new crinane-type alkaloid, 6-epihydroxypowelline (1), together with six known alkaloids, lycorine (2), 2-O-acetyllycorine (3), deacetylbowdensine (4), 1-epideacetylbowdensine (5), 8-demethyl-3-oxomaritidine (6), and (-)-marithamine (7) were isolated from the whole parts of the Crinum latifolium L. in Vietnam. The structure identification of all compounds was determined by 1D, 2D-NMR as well as HR-ESI-MS spectroscopic techniques. The absolute configuration of these compounds was established by the ECD data. In addition, in vitro inhibition of acetylcholinesterase (AChE) activities was assessed for all isolated alkaloids. All alkaloids had AChE inhibitory effects, with IC50 values ranging from 32.65 ± 2.72 to 212.76 ± 8.30 µM and compound 3 displayed the strongest inhibition of AChE, with IC50 values of 32.65 ± 2.72 µM (in comparison to the reference drug, galanthamine, which had an IC50 of 2.40 ± 0.45 µM).
6.Alkaloids with Acetylcholinesterase Inhibitory Activities from Crinum latifolium L.
Vu Thi TRANG ; Pham Van CONG ; Nguyen Van DAN ; Nguyen Thi Thu HIEN ; Do Thanh TUAN ; Le Tuan ANH ; Hoang Dac THANG ; Ngo Viet DUC ; Hoang Le Tuan ANH
Natural Product Sciences 2024;30(4):304-308
A new crinane-type alkaloid, 6-epihydroxypowelline (1), together with six known alkaloids, lycorine (2), 2-O-acetyllycorine (3), deacetylbowdensine (4), 1-epideacetylbowdensine (5), 8-demethyl-3-oxomaritidine (6), and (-)-marithamine (7) were isolated from the whole parts of the Crinum latifolium L. in Vietnam. The structure identification of all compounds was determined by 1D, 2D-NMR as well as HR-ESI-MS spectroscopic techniques. The absolute configuration of these compounds was established by the ECD data. In addition, in vitro inhibition of acetylcholinesterase (AChE) activities was assessed for all isolated alkaloids. All alkaloids had AChE inhibitory effects, with IC50 values ranging from 32.65 ± 2.72 to 212.76 ± 8.30 µM and compound 3 displayed the strongest inhibition of AChE, with IC50 values of 32.65 ± 2.72 µM (in comparison to the reference drug, galanthamine, which had an IC50 of 2.40 ± 0.45 µM).
7.Alkaloids with Acetylcholinesterase Inhibitory Activities from Crinum latifolium L.
Vu Thi TRANG ; Pham Van CONG ; Nguyen Van DAN ; Nguyen Thi Thu HIEN ; Do Thanh TUAN ; Le Tuan ANH ; Hoang Dac THANG ; Ngo Viet DUC ; Hoang Le Tuan ANH
Natural Product Sciences 2024;30(4):304-308
A new crinane-type alkaloid, 6-epihydroxypowelline (1), together with six known alkaloids, lycorine (2), 2-O-acetyllycorine (3), deacetylbowdensine (4), 1-epideacetylbowdensine (5), 8-demethyl-3-oxomaritidine (6), and (-)-marithamine (7) were isolated from the whole parts of the Crinum latifolium L. in Vietnam. The structure identification of all compounds was determined by 1D, 2D-NMR as well as HR-ESI-MS spectroscopic techniques. The absolute configuration of these compounds was established by the ECD data. In addition, in vitro inhibition of acetylcholinesterase (AChE) activities was assessed for all isolated alkaloids. All alkaloids had AChE inhibitory effects, with IC50 values ranging from 32.65 ± 2.72 to 212.76 ± 8.30 µM and compound 3 displayed the strongest inhibition of AChE, with IC50 values of 32.65 ± 2.72 µM (in comparison to the reference drug, galanthamine, which had an IC50 of 2.40 ± 0.45 µM).
8.Result of production of standard Albumin from human plasma.
Phan Trung Do ; Duong Tuan Pham ; Hien Thi Do ; Ha Diem Vo ; Thuy Thi Nguyen ; Thin Duy Ngo ; Phuc Hanh Hoang ; Tri Anh Nguyen
Journal of Medical Research 2007;52(5):1-6
Background: Human albumin was produced and used in many countries. Cohn's technique had been used to precipitate albumin from human plasma. This technique was easy and cheap and the quality of the product was good. In Vietnam, human albumin had to import, but the prices was very expensive. Vietnam was having good plasma in large quantity and high quality. That\u2019s why research on production plasma albumin was essential.\r\n", u"Objectives: This study aimed at using Cohn's technique improved by Drohan and Van - Aken to produce standard albumin from human plasma. Subjects and method: Human plasma detected VIII-factor was used for present study. Plasma \ufffd?albumin was precipitated by ethanol at low temperature and pH. The collected albumins have been liophilizated and storage at 40C. The quality and quantity of Albumin was evaluated by quantitative analysis and protein \ufffd?electrophoresis. Results: The 418g of albumin powder was produced from 16 liters of plasma detected F \ufffd?VIII. The quality of this albumin come up to standard (>95%) and quantity of albumin collected from one liter of this plasma was 26g. Conclusion: In the Vietnamese condition, the technique of Cohn can be used to produce standard albumin for treatment.\r\n", u'
Albumins/ standards
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Plasma
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9.Applied research into the production process of gama - Globulin from Human Plasma and Standard gama - Globulin with Rich of Anti \u2013 HBs
Phan Trung Do ; Duong Tuan Pham ; Hien Thi Do ; Thuy Thi Tran ; Thin Duy Ngo ; Phuc Hanh Hoang ; Hai Xuan Le ; Tri Anh Nguyen
Journal of Medical Research 2008;0(1):67-71
Introduction: The need for gama \u2013 globulin, especially gama - globulin - anti \u2013 HBs, is huge in Vietnam. A number of patients cannot to afford use them due to the high price as they are imported. Meanwhile, Vietnam has high quality input sources for producing gama \u2013 globulin. \r\n', u'Objectives: To study the production process of gama - Globulin from Human Plasma and Standard gama - Globulin with Rich of Anti \u2013 HBs. \r\n', u'Subjects and method: 168 samples of human plasma from voluntary blood donors, which had been screened with for transfusion transmittable infections (TTLs), were chosen as plasma with rich of anti - HBs. The plasma with anti - HBsAg was precipitated with ethanol 25%, pH 6,9 to gain gama - globulin with rich anti - HBs, which was dried by Dutch Ly - 3 - TTE machine. Activation of anti - HBs gama - globulin was identified by a standard method of the degree of antibody specific for anti - HBsAg kit of BIORAD, \r\n', u'Results: The purity of the gama - globulin achieved was 93%, which was almost equal with the results of some foreign researchers (7.8), the activation of anti - HBs was 1:128 dilution degree. The productivity of gama - globulin gaining from 1 litter plasma was 6.0 gram. This new issue was first demonstrated in Vietnam. \r\n', u'Conclusion: We can domestically produce anti-Bs gama - globulin with high degree of activeness (1:128) from human plasma by the precipitating method with ethanol, pH and low temperature. \r\n', u'
Human plasma
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gama - globulin - anti - HBs
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Precipitation of ethanol
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pH and low temperature
10.Identification of Enterovirus C105 for the first time in New Zealand
Cong Thanh Duong ; Tran Hien Nguyen ; Anh Tuan Nguyen ; Thi Thanh Ha Hoang ; Hong Thang Pham ; Thi THanh Ha Nguyen ; Anh Tuan Le ; Dai Quang Tran ; Hong Tram Tran ; Le Hai Nguyen ; Thi Thu Huong Phan ; Hai Son Vo ; Hoang Duc Bui ; Thien Nga Nguyen ; David Jacka ; Keith Sabin
Western Pacific Surveillance and Response 2015;6(1):52-54
In this report we describe a new approach in HIV sentinel surveillance that was piloted in Viet Nam in 2009 and is currently being rolled out in all provinces. It comprises a brief behavioural questionnaire added to the HIV sentinel surveillance surveys conducted routinely among people who inject drugs, female sex workers and men who have sex with men. Timely reporting of data from this system has resulted in improvements to HIV prevention efforts for most at-risk populations.