1.Z-reconstruction of muscular membrane of nasal vestibule for repair of secondary cleft lip nose deformity
Journal of Practical Medicine 2002;435(11):26-27
From 1998 to 1999, 25 patients were operated to repair the secondary nasal deformity after initial congenital cleft lip and palate reconstruction. Age of patients ranged from 11 to 23, 6 males, 19 females, inwhich 11 patients have upper cleft lip alon and 14 patients have cleft lip with cleft palate. This is an adjunctive surgery for nasal deformity recontruction using cartilage interventions. Criteria of evaluation: good: the vestibular membrane disappeared, nasal ventilation is good. Moderate: the vestibular membrane is still, nasal ventilation is good. Poor: there was not improvement. Result: good result was achieved in 11 patients (44%), moderate in 8 patients (32%) and poor result in 24%
Muscle Contraction
;
Abnormalities
2.Ethanol extracts of Scutellaria baicalensis protect against lipopolysaccharide-induced acute liver injury in mice
Thanh Nguyen Hai ; Le Anh Tuan ; Huu Nguyen Tung ; Duc Vu Loi ; Kim Dang Thu ; Thanh Bui Tung
Asian Pacific Journal of Tropical Biomedicine 2015;(9):733-738
To investigated the protective potential of ethanol extracts of Scutellaria baicalensis (S. baicalensis ) against lipopolysaccharide (LPS)-induced liver injury. Methods: Dried roots of S. baicalensis were extracted with ethanol and concentrated to yield a dry residue. Mice were administered 200 mg/kg of the ethanol extracts orally once daily for one week. Animals were subsequently administered a single dose of LPS (5 mg/kg of body weight, intraperitoneal injection). Both protein and mRNA levels of cytokines, such as tumor necrosis factor alpha, interleukin-1β, and interleukin-6 in liver tissues were evaluated by ELISA assay and quantitative PCR. Cyclooxygenase-2, inducible nitric oxide synthase, and nuclear factor-κB protein levels in liver tissues were analyzed by western blotting. Results: Liver injury induced by LPS significantly increased necrosis factor alpha, interleukin-1β, interleukin-6, cyclooxygenase-2, inducible nitric oxide synthase, and nuclear factor-κB in liver tissues. Treatment with ethanol extracts of S. baicalensis prevented all of these observed changes associated with LPS-induced injury in liver mice. Conclusions: Our study showed that S. baicalensis is potentially protective against LPS-induced liver injury in mice.
3.Evaluate on epidemic supervision and propose solutions to protect healthy for soldiers and people in malaria epidemic area.
Ngo Van Ly ; Thuan Khanh Le ; Loc Ba Ly ; Doan Van Nguyen ; Sinh Cong Nguyen ; Tuan Dinh Trinh ; Duc Ai Quach ; Thao Duc Nguyen ; Thuc Duy Nguyen ; Binh Van Nguyen ; Thang Duc Do
Journal of Malaria and parasite diseases Control 2003;0(1):13-24
Background: Coordinating between soldiers and people bring significant results in protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Objectives: To evaluate epidemic supervision and propose solutions protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Subjects and methods: A retrospective cross sectional study was carried out on two provinces Binh Phuoc and Dak Lak\r\n', u'Results: there was 4 main disease types were fever, tuberculosis, diarrhea and malaria. Malaria at investigated times still accounted high rate comparing with general fever rate. Malaria risk contained in people living or working in forest and mountain field; free emigrants; armed forces and border guard. These subjects needed to improve regularly protection from malaria. Communication of health education is one of important method to prevent and control malaria.\r\n', u'Conclusion: It is necessary to implement strong methods (such as providing insecticide treated bed nets, indoor residual spray) to prevent and control malaria. \r\n', u'
Epidemic supervision
;
healthy
;
soldier
;
malaria epidemic area.
4.Outcomes of liver transplantation for hepatocellular carcinoma:Experiences from a Vietnamese center
Khai Viet NINH ; Dang Hai DO ; Trung Duc NGUYEN ; Phuong Ha TRAN ; Tuan HOANG ; Dung Thanh LE ; Nghia Quang NGUYEN
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(1):34-41
Background:
s/Aims: Liver transplantation (LT) provides a favorable outcome for patients with hepatocellular carcinoma (HCC) and was launched in Vietnam in 2004. In this study, we evaluated the short-term and long-term outcomes of LT and its risk factors.
Methods:
This retrospective study analyzed HCC patients who underwent LT at Viet Duc University hospital, Vietnam, from 01/2012–03/2022. The following data were gathered: demographics, virus infection, tumor characteristics, alpha-fetoprotein (AFP) level, Child-Pugh and MELD scores, selection criteria, type of LT, complications, 30-day mortality, and disease-free and overall survival (DFS and OS).
Results:
Fifty four patients were included, the mean age was 55.39 ± 8.46 years. Nearly 90% had hepatitis B virus-related HCC. The median (interquartile range) AFP level was 16.2 (88.7) ng/mL. The average MELD score was 10.57 ± 5.95; the rate of Child-Pugh A and B were 70.4% and 18.5%, respectively. Nearly 40% of the patients were within Milan criteria, brain-dead donor was 83.3%. Hepatic and portal vein thrombosis occurred in 0% and 1.9%, respectively; hepatic artery thrombosis 1.9%, biliary leakage 5.6%, and postoperative hemorrhage 3.7%. Ninety-day mortality was 5.6%. Five-year DFS and OS were 79.3% and 81.4%, respectively. MELD score and ChildPugh score were predictive factors for DFS and OS (p < 0.05). In multivariate analysis, Child-Pugh score was the only significant factor (p < 0.05).
Conclusions
In Vietnam, LT is an effective therapy for HCC with an acceptable complication rate, mortality rate, and good survival outcomes, and should be further encouraged.
5.Outcomes of liver transplantation for hepatocellular carcinoma:Experiences from a Vietnamese center
Khai Viet NINH ; Dang Hai DO ; Trung Duc NGUYEN ; Phuong Ha TRAN ; Tuan HOANG ; Dung Thanh LE ; Nghia Quang NGUYEN
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(1):34-41
Background:
s/Aims: Liver transplantation (LT) provides a favorable outcome for patients with hepatocellular carcinoma (HCC) and was launched in Vietnam in 2004. In this study, we evaluated the short-term and long-term outcomes of LT and its risk factors.
Methods:
This retrospective study analyzed HCC patients who underwent LT at Viet Duc University hospital, Vietnam, from 01/2012–03/2022. The following data were gathered: demographics, virus infection, tumor characteristics, alpha-fetoprotein (AFP) level, Child-Pugh and MELD scores, selection criteria, type of LT, complications, 30-day mortality, and disease-free and overall survival (DFS and OS).
Results:
Fifty four patients were included, the mean age was 55.39 ± 8.46 years. Nearly 90% had hepatitis B virus-related HCC. The median (interquartile range) AFP level was 16.2 (88.7) ng/mL. The average MELD score was 10.57 ± 5.95; the rate of Child-Pugh A and B were 70.4% and 18.5%, respectively. Nearly 40% of the patients were within Milan criteria, brain-dead donor was 83.3%. Hepatic and portal vein thrombosis occurred in 0% and 1.9%, respectively; hepatic artery thrombosis 1.9%, biliary leakage 5.6%, and postoperative hemorrhage 3.7%. Ninety-day mortality was 5.6%. Five-year DFS and OS were 79.3% and 81.4%, respectively. MELD score and ChildPugh score were predictive factors for DFS and OS (p < 0.05). In multivariate analysis, Child-Pugh score was the only significant factor (p < 0.05).
Conclusions
In Vietnam, LT is an effective therapy for HCC with an acceptable complication rate, mortality rate, and good survival outcomes, and should be further encouraged.
6.Outcomes of liver transplantation for hepatocellular carcinoma:Experiences from a Vietnamese center
Khai Viet NINH ; Dang Hai DO ; Trung Duc NGUYEN ; Phuong Ha TRAN ; Tuan HOANG ; Dung Thanh LE ; Nghia Quang NGUYEN
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(1):34-41
Background:
s/Aims: Liver transplantation (LT) provides a favorable outcome for patients with hepatocellular carcinoma (HCC) and was launched in Vietnam in 2004. In this study, we evaluated the short-term and long-term outcomes of LT and its risk factors.
Methods:
This retrospective study analyzed HCC patients who underwent LT at Viet Duc University hospital, Vietnam, from 01/2012–03/2022. The following data were gathered: demographics, virus infection, tumor characteristics, alpha-fetoprotein (AFP) level, Child-Pugh and MELD scores, selection criteria, type of LT, complications, 30-day mortality, and disease-free and overall survival (DFS and OS).
Results:
Fifty four patients were included, the mean age was 55.39 ± 8.46 years. Nearly 90% had hepatitis B virus-related HCC. The median (interquartile range) AFP level was 16.2 (88.7) ng/mL. The average MELD score was 10.57 ± 5.95; the rate of Child-Pugh A and B were 70.4% and 18.5%, respectively. Nearly 40% of the patients were within Milan criteria, brain-dead donor was 83.3%. Hepatic and portal vein thrombosis occurred in 0% and 1.9%, respectively; hepatic artery thrombosis 1.9%, biliary leakage 5.6%, and postoperative hemorrhage 3.7%. Ninety-day mortality was 5.6%. Five-year DFS and OS were 79.3% and 81.4%, respectively. MELD score and ChildPugh score were predictive factors for DFS and OS (p < 0.05). In multivariate analysis, Child-Pugh score was the only significant factor (p < 0.05).
Conclusions
In Vietnam, LT is an effective therapy for HCC with an acceptable complication rate, mortality rate, and good survival outcomes, and should be further encouraged.
7.Outcomes of liver transplantation for hepatocellular carcinoma:Experiences from a Vietnamese center
Khai Viet NINH ; Dang Hai DO ; Trung Duc NGUYEN ; Phuong Ha TRAN ; Tuan HOANG ; Dung Thanh LE ; Nghia Quang NGUYEN
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(1):34-41
Background:
s/Aims: Liver transplantation (LT) provides a favorable outcome for patients with hepatocellular carcinoma (HCC) and was launched in Vietnam in 2004. In this study, we evaluated the short-term and long-term outcomes of LT and its risk factors.
Methods:
This retrospective study analyzed HCC patients who underwent LT at Viet Duc University hospital, Vietnam, from 01/2012–03/2022. The following data were gathered: demographics, virus infection, tumor characteristics, alpha-fetoprotein (AFP) level, Child-Pugh and MELD scores, selection criteria, type of LT, complications, 30-day mortality, and disease-free and overall survival (DFS and OS).
Results:
Fifty four patients were included, the mean age was 55.39 ± 8.46 years. Nearly 90% had hepatitis B virus-related HCC. The median (interquartile range) AFP level was 16.2 (88.7) ng/mL. The average MELD score was 10.57 ± 5.95; the rate of Child-Pugh A and B were 70.4% and 18.5%, respectively. Nearly 40% of the patients were within Milan criteria, brain-dead donor was 83.3%. Hepatic and portal vein thrombosis occurred in 0% and 1.9%, respectively; hepatic artery thrombosis 1.9%, biliary leakage 5.6%, and postoperative hemorrhage 3.7%. Ninety-day mortality was 5.6%. Five-year DFS and OS were 79.3% and 81.4%, respectively. MELD score and ChildPugh score were predictive factors for DFS and OS (p < 0.05). In multivariate analysis, Child-Pugh score was the only significant factor (p < 0.05).
Conclusions
In Vietnam, LT is an effective therapy for HCC with an acceptable complication rate, mortality rate, and good survival outcomes, and should be further encouraged.
8.Discordance between quantitative ultrasound and dual-energy X-ray absorptiometry in bone mineral density: The Vietnam Osteoporosis Study
Huy G. NGUYEN ; Khanh B. LIEU ; Thao P. HO-LE ; Lan T. HO-PHAM ; Tuan V. NGUYEN
Osteoporosis and Sarcopenia 2021;7(1):6-10
Objectives:
Calcaneal quantitative ultrasound measurement (QUS) has been considered an alternative to dual-energy X-ray absorptiometry (DXA) based bone mineral density (BMD) for assessing bone health. This study sought to examine the utility of QUS as an osteoporosis screening tool by evaluating the correlation between QUS and DXA.
Methods:
The study was a part of the Vietnam Osteoporosis Study that involved 1270 women and 773 men aged 18 years and older. BMD at the femoral neck, total hip and lumbar spine was measured using DXA. Osteoporosis was diagnosed based on the femoral neck T-score using World Health Organization criteria. Broadband ultrasound attenuation (BUA) at the calcaneus was measured by QUS. The concordance between BUA and BMD was analyzed by the linear regression model.
Results:
In all individuals, BUA modestly correlated with femoral neck BMD (r = 0.35; P < 0.0001) and lumbar spine BMD (r = 0.34; P < 0.0001) in both men and women. In individuals aged 50 years and older, approximately 16% (n = 92/575) of women and 3.2% (n = 10/314) of men were diagnosed to have osteoporosis. Only 0.9% (n = 5/575) women and 1.0% (n = 3/314) men were classified as “Low BUA”. The kappa coefficient of concordance between BMD and BUA classification was 0.09 (95% CI, 0.04 to 0.15) for women and 0.12 (95% CI, 0.03 to 0.22) for men.
Conclusions
In this population-based study, QUS BUA modestly correlated with DXA BMD, suggesting that BUA is not a reliable method for screening of osteoporosis.
9.Discordance between quantitative ultrasound and dual-energy X-ray absorptiometry in bone mineral density: The Vietnam Osteoporosis Study
Huy G. NGUYEN ; Khanh B. LIEU ; Thao P. HO-LE ; Lan T. HO-PHAM ; Tuan V. NGUYEN
Osteoporosis and Sarcopenia 2021;7(1):6-10
Objectives:
Calcaneal quantitative ultrasound measurement (QUS) has been considered an alternative to dual-energy X-ray absorptiometry (DXA) based bone mineral density (BMD) for assessing bone health. This study sought to examine the utility of QUS as an osteoporosis screening tool by evaluating the correlation between QUS and DXA.
Methods:
The study was a part of the Vietnam Osteoporosis Study that involved 1270 women and 773 men aged 18 years and older. BMD at the femoral neck, total hip and lumbar spine was measured using DXA. Osteoporosis was diagnosed based on the femoral neck T-score using World Health Organization criteria. Broadband ultrasound attenuation (BUA) at the calcaneus was measured by QUS. The concordance between BUA and BMD was analyzed by the linear regression model.
Results:
In all individuals, BUA modestly correlated with femoral neck BMD (r = 0.35; P < 0.0001) and lumbar spine BMD (r = 0.34; P < 0.0001) in both men and women. In individuals aged 50 years and older, approximately 16% (n = 92/575) of women and 3.2% (n = 10/314) of men were diagnosed to have osteoporosis. Only 0.9% (n = 5/575) women and 1.0% (n = 3/314) men were classified as “Low BUA”. The kappa coefficient of concordance between BMD and BUA classification was 0.09 (95% CI, 0.04 to 0.15) for women and 0.12 (95% CI, 0.03 to 0.22) for men.
Conclusions
In this population-based study, QUS BUA modestly correlated with DXA BMD, suggesting that BUA is not a reliable method for screening of osteoporosis.
10.Identification of Enterovirus C105 for the first time in New Zealand
Cong Thanh Duong ; Tran Hien Nguyen ; Anh Tuan Nguyen ; Thi Thanh Ha Hoang ; Hong Thang Pham ; Thi THanh Ha Nguyen ; Anh Tuan Le ; Dai Quang Tran ; Hong Tram Tran ; Le Hai Nguyen ; Thi Thu Huong Phan ; Hai Son Vo ; Hoang Duc Bui ; Thien Nga Nguyen ; David Jacka ; Keith Sabin
Western Pacific Surveillance and Response 2015;6(1):52-54
In this report we describe a new approach in HIV sentinel surveillance that was piloted in Viet Nam in 2009 and is currently being rolled out in all provinces. It comprises a brief behavioural questionnaire added to the HIV sentinel surveillance surveys conducted routinely among people who inject drugs, female sex workers and men who have sex with men. Timely reporting of data from this system has resulted in improvements to HIV prevention efforts for most at-risk populations.