The conflict between doctors′ special right to intervene and patients′ right of informed consent is a main cause of the current tense doctor-patient relationship with the absence of related legislation.This article gave suggestions on legislation and possible ways for solving the problems after analyzing the two rights from the angles of basic connotation,research progress of comparative law,and the underlying reason for the two rights′ conflict.

Objective To develop a prediction scale for mental disorders in servicemen, and examine the reliability and validity of this scale. Methods The mental disorders prediction scale was developed by exploring the risk factors inducing the mental disorders. The initial scale included 11 subscales and 102 items. One thousand and four hundreds of soldiers were chosen by random cluster sampling, and tested with this scale, of whom 54 soldiers were tested with Chinese Military Mental Health Scale (CMMHS), 61 with Eysenck Personality Questionnaire (EPQ) at the same time, and 53 were retested after 1 week. The reliability and validity of the scale were examined by Exploratory Factor Analysis and Correlation Analysis. Results According to the results of factor analysis, 11 factors were extracted, named unhealthy defense mechanism, psychosis, depression, personality disturbance, mania, social support deficiency, introversion, family and past history, stressor, neurosis, and growth experience, respectively, and there were 96 items in the formal scale when one lie factor was added. The test-retest correlation coefficients of total scale and subscales were 0.397-0.867 (P

Objective Tamarix ramosissima is the host plant of Cistanche tubulosa. The chemical cons-tituents of T. ramosissima were studied in order to improve the development of culture base of C. tubulosa and look for the base for exploitation of T. ramossisma. Methods Various chromatographic techniques were employed for the isolation and purification of the constituents including silica gel, Sephadex LH-20, and preparative HPLC. The structures of compounds were elucidated by chemical and spectral analyses (IR, UV, NMR, and MS). Results Twelve compounds have been isolated from the tender wattle of T. ramosissima, their structures were elucidated as aleuritolic acid (D-friedoolean-14-en-3-ol-28-oic acid, Ⅰ), aleuritolonic acid (D-friedoolean-14-en-3-one-28-oic acid, Ⅱ), rhamnocitrin (Ⅲ), ellagic acid-3, 3′-dimethyl ether (Ⅳ), rhamnetin (Ⅴ), kaemferol (Ⅵ), isoferulic acid (Ⅶ), aromadendrin (Ⅷ), (2?,3?)-dihydrorhamnetin (Ⅸ), quercetin (Ⅹ), 7, 4′-dimethoxykaemferol (Ⅺ), 3-methoxykaemferol (ⅩⅡ). Conclusion Among these compounds, Ⅰ, Ⅱ, Ⅳ, Ⅴ, Ⅷ, Ⅸ, and ⅩⅡ are isolated from the plants of Tamarix L. for the first time.

Objective To investigate the influence of electroacupuncture (EA) on behaviors and GR, NR2B in hippocampal of the chronic stress depression rats. Methods Forty SD rats were divided into control, model, EA and Prozac groups. Chronic stress model was established by using chronic mixed stimulation. Observe the behaviors caused by chronic stress, including changes of spontaneous movements in Open-field test, learning-memory behavior in"Y"-maze test and stillness time in forced-swimming test. The expression of GR and NR2B in hippocampal tissue was detected by immunohistochemical technology. Results Compared with control group, the results of spontaneous movements, stillness swimming time and learning-memory behaviors of the chronic stress model rats were declined significantly (P

Objective:To investigate the in vitro release behavior and stability of diphenyl diester suspension. Methods:The dis-solution of biphenyl diester dry suspension was detected by HPLC, and the effects of different stirring speed (50, 75, 100 r·min-1 ) and different dissolution media (pH 6. 8 phosphate buffer, 0. 05 mol·L-1 hydrochloric acid solution,water,pH 4. 5 acetate buffer) on dissolution were investigated. The influencing factors testing ( high temperature, high humidity and strong light exposure) , accelerated stability testing[the temperature of (37 ± 5) ℃ and the relative humidity of 76％ ± 5％] and long-term stability testing[(25 ± 3) ℃and the relative humidity of 60％ ± 5 ％] of biphenyl diester dry suspension were carried out. Results:The dissolution behavior of bi-phenyl diester suspension in pH 6. 8 phosphate buffer (50 r·min-1 ) was faster and smoother. The results of influencing factors testing showed that biphenyl diester dry suspension should not be stored under the conditions of high temperature and high humidity. After the samples were stored under the conditions of accelerated testing and long-term stability testing for 6 months, the indicators did not change significantly. Conclusion:The in vitro release of prepared biphenyl diester dry suspension meets the requirements with promis-ing stability.

OBJECTIVE:To systematically review the clinical efficacy of Tibolone tablet in the treatment of senile vaginitis, and provide evidence-based reference for clinical treatment. METHODS:Retrieved from PubMed,Medline,CJFD,CBM,VIP and Wangfang Database,randomized controlled trials(RCT)about Tibolone tablet in the treatment of senile vaginitis were collct-ed. Meta-analysis was performed by using Rev Man 5.2 software after data extract and quality evaluation. RESULTS:Totally 10 RCTs were enrolled,involving 909 patients. Results of Meta-analysis showed Tibolone tablet can significantly improve the cure rate of senile vaginitis [RR=1.46,95%CI(1.32,1.61),P<0.001],maturation vaginal cell index score [SMD=1.83,95%CI(1.65, 2.01),P<0.001] and vaginal health score [SMD=1.56,95%CI(1.21,1.92),P<0.001],reduce recurrence rate [RR=0.07,95%CI (0.02,0.18),P<0.001] and vaginitis score [SMD=-1.44,95%CI(-1.79,-1.08),P<0.001]. CONCLUSIONS:Tibolone tablet has good clinical efficacy in the treatment of senile vaginitis,it can improve the vaginal mucosa estrogen and vaginal environment, reduce recurrence rate.

Objective To perform fetal karyotyping by percutaneous umbilical blood sampling guided by color Doppler ultrasonography in fetuses with congenital cardiac anomalies. Methods Fetal blood samples obtained by color Doppler ultrasound-guided cordocentesis in 56 fetuses with cardiac abnormalities detected by fetal echocardiography were taken for karyotyping.Fetuses were monitored post operation. Results The procedures were successfully performed in all cases and no procedure-related complications occurred.Six cases with abnormal karyotypes, 1 trisomy 21,2 trisomy 18,1 trisomy 13,1 trisomy AO and 1 cases 47XYY were identified and pre-operation ultrasonography detected multiple system anomalies besides cardiac anomalies in them. Conclusions Color Doppler ultrasonography facilitated percutaneous umbilical blood sampling by clear umbilical vein imaging and shortening the operation time.Abnormal karyotypes in fetuses with cardiac anomalies seemed to be related with multiple system anomalies.

Objective To evaluate the capacity of air quality test of indoor air quality test agencies in Beijing. Methods 59 laboratories participated the evaluation. The standard reference (SRF) material, ammonia and benzene, were used as the test items and the national standard methods were used in the determination, the capacity evaluation was done by comparing the test values and Robust Z-Score. Results 28 laboratories (47.5%) presented a satisfactory result for both ammonia and benzene determination, 3 gave an unsatisfactory result for both items, 28 showed an unsatisfactory result or a result with some error in alternative1 item. Conclusion In the present study, only 47.5% of the investigated laboratories are satisfied. There are still some problems in the capacity of air quality test of test agencies in Beijing and the test capacity need to be improved.

Objective To explore the mechanism of siRNA targeted hTERT gene to inhibit bladder cancer T24 cell growth by decreasing c-myc and TGF-?1 expression. Methods shRNA-hTERT-pTZU6+1 vectors were constructed by RNAi-DNA vector technique, then the vectors were transfected into bladder cancer T24 cells,and the most effective vector and its optimal concentration were screened using RT-PCR to detect hTERT expression in T24 cells.The T24 cell growth, the alternative of cell phase,the expression of hTERT,c-myc and TGF-?1 were detected by flow cytometry,RT-PCR and immunohistochemistry. Results Three shRNA-hTERT-pTZU6+1 vectors were successfully constructed.The most effective vector was ph2-shRNA vector,and its optimal concentration was 1.0 ?g.This vector decreased the cell growth and the cell number of S phase from 65.2% to 38.6%,increased the cell number of G0/G1 phase from 32.0% to 57.9%,and attenuated both mRNA and protein expressions of hTERT,c-myc and TGF-?1 in T24 cells. Conclusions Targeted hTERT gene with siRNA may inhibit the cell proliferation of bladder cancer;down-regulating hTERT expression by attenuating the expression of c-myc and TGF-?1 is probably involved in the mechanism.