The coupling procedure of antimalarial agent (SR2) onto polymeric carrier (SR1) by covalent bond (amide linkage) was studied. Some factors of drug coupling reaction was investigated.
Antimalarials ; Pharmaceutical Preparations ; drug therapy

The investigation was performed on employees and workers who contact with chemicals at 9 institutions using various substances in the process of production of paint, rubber, shoe and wood articles in Ha Noi, Hai Phong and Da Nang. Results showed that the current regulations were not complied preserve and use of chemical substance, without emergency equipments available for working staff and environment. A high rate of workers had not been educate on chemical safety and a high rate of work place and facilities had not guideline for using chemical substances.
Chemistry/manpower ; Paint ; Rubber ; Shoes ; Wood

4 groups of subjects including 1.590 workers with occupational diseases and exposed to the risks. 175 managers, 153 health workers, 32 officals of the Labor – Invalide – Social services, social insurance in 37 factories in 7 provinces/cities: Thai Nguyen, Quang Ninh, Hanoi, Nam Dinh, Nghe An, Hue and HoChiMinh city, were enrolled into study performed from September 2001 to June 2002. The study had showed a rate of 93.8% exposed subjects underwent regular health examination of low quality. The result table delayed < 2 weeks with the cost of 35.000 VND for each subjects. In > 71.5% of fatories, occupational health examinations were conducted. The prevalence of pneumoconiosis was 94% and the cost of consultation 83.000 VND for each. There was a rather good realization of the regime of health care allowance and subsidy.
Periodicals ; Occupational Diseases ; Risk Factors

One method to determine the content of chitosan present in Pokysan cream has been developed. Chitosan was separated from Pokysan by dissolving the cream in acidic solution, extracted by chemical mixtures of I and II, which were prepared by laboratory of polymers in medico – pharmacy, and then collecting the precipitate of chitosan in the alkaline medium. This precipitate was then qualified by Lugol reagent and IR spectra. Collected chitosan precipitate was also qualified and quantified. These results proved that chitosan has been included in Pokysan cream and our method is confident
Chitosan ; Evaluation Studies ; Laboratories

The subjects consisted of 15 processing households and 150 processing direct employees. Intervention of “Health promotion at workplaces for processing village households” according to the guide-line of WHO was implemented. The study was firstly carried out in Tien Ngoai food processing village, Khac Niem commune, Bac Ninh province from 2002-2003. The results showed that the intervention was successful. Tien Ngoai village developed its down rule, in which there were regulation on environmental protection, occupational safety. The village also established a fund for these activities. Each household carried out at least 3 improvements of working and living conditions. Commune health station in cooperation with preventive medicine centers organized medical examination and consultation for handicraft employees. Improving awareness of employees on occupational safety and environmental protection were done in different ways.
Health ; Food

Protein trace present in chitin/chitosan product has been determined by our proposed method in which protein trace included in chitin/chitosan was extracted by refraction in 10% NaOH solution at 100oC for 5 hours. Chitin/Chitosan precipitate was discarded. protein trace in the solution was restored by neutralizing with HCl 10N to get the yellow powder. This powder was then analyzed for total nitrogen content by Kjeldahl method. The control method was conducted at the same procedure excepted from the presence of 10% NaOH. The results of different chitin/chitosan samples obtained from these two methods showed that amount of protein trace obtained from above proposed method was somewhat higher than that of the control one. Besides, the purified chitosan sample gave the lower protein trace content than that of the technical chitosan sample as well as chitin one. Protein trace bound between macromolecules of chitin/chitosan was separated in the proposed method by boiling water under alkaline condition whereas it was not completely separated in the control method because sodium hydroxide was absent.
Chitin ; Chitosan ; Proteins

Biopolymeric membrane is made on the polysaccharide of natural origin according to our own technological process. It is a high bioactive, biocompatible, biodegradable polymeric membrane with effective action for treating wound healing. The preliminary results of clinical study suggested that the membrane were effectively used as biologic dressings for the treatment of donor sites of skin graft, partial thickness burns and granulation tissue. The wound surface after healing was smooth and flexible. The biopolymeric membrane is not only suitable for the treatment of burn wounds, but also it can applied for the skin surgery with excellent results.
burns ; therapeutics

400 workers in 4 coalmines were investigated, on the medical records, physical and laboratorial examinations. Working environment was studied. The common diseases observed are silicopneumoconiosis (5.82%) and mycodermatitis (64.69%).
Environment ; Coal ; Health status

Khanh Hoa fishery has not paid much attention on supporting and training of working safety, navigate safety and rescurity. Some dead accidents happening on the sea would have been cured by that problem. We have made some practical recommendations for prevention of working accidents and health protection for fishermen
Occupational Health ; Accidents, Occupational

Occupational lung disease (silicosis) in Viet Nam occupied the highest rate among occupational diseases and have an increasingly trend in a near future. The most important branches are coal mines, heavy industry, rock exploitation, construction, etc. Studies on prevalence and estimating the number of cases are important to set - up the prevention strategies for control and elimination of silicosis in Viet Nam.
Occupational Diseases ; Silicosis