1.A method for determination of trace content of protein in material of chitin/chitosan
Pharmaceutical Journal 2002;319(11):23-24
Protein trace present in chitin/chitosan product has been determined by our proposed method in which protein trace included in chitin/chitosan was extracted by refraction in 10% NaOH solution at 100oC for 5 hours. Chitin/Chitosan precipitate was discarded. protein trace in the solution was restored by neutralizing with HCl 10N to get the yellow powder. This powder was then analyzed for total nitrogen content by Kjeldahl method. The control method was conducted at the same procedure excepted from the presence of 10% NaOH. The results of different chitin/chitosan samples obtained from these two methods showed that amount of protein trace obtained from above proposed method was somewhat higher than that of the control one. Besides, the purified chitosan sample gave the lower protein trace content than that of the technical chitosan sample as well as chitin one. Protein trace bound between macromolecules of chitin/chitosan was separated in the proposed method by boiling water under alkaline condition whereas it was not completely separated in the control method because sodium hydroxide was absent.
Chitin
;
Chitosan
;
Proteins
2.Preliminary results of study on manufacture of biological polymeric membrane for the treatment of burns
Pharmaceutical Journal 1998;272(12):17-19
Biopolymeric membrane is made on the polysaccharide of natural origin according to our own technological process. It is a high bioactive, biocompatible, biodegradable polymeric membrane with effective action for treating wound healing. The preliminary results of clinical study suggested that the membrane were effectively used as biologic dressings for the treatment of donor sites of skin graft, partial thickness burns and granulation tissue. The wound surface after healing was smooth and flexible. The biopolymeric membrane is not only suitable for the treatment of burn wounds, but also it can applied for the skin surgery with excellent results.
burns
;
therapeutics
3.The influence of working environment on coal exploiting worker's health state
Journal of Medical and Pharmaceutical Information 2001;8():24-27
400 workers in 4 coalmines were investigated, on the medical records, physical and laboratorial examinations. Working environment was studied. The common diseases observed are silicopneumoconiosis (5.82%) and mycodermatitis (64.69%).
Environment
;
Coal
;
Health status
4.Some aspects of occupational health in fishery at Khanh Hoa 1996-1997, suggestions for improvement
Journal of Preventive Medicine 1999;9(2):48-54
Khanh Hoa fishery has not paid much attention on supporting and training of working safety, navigate safety and rescurity. Some dead accidents happening on the sea would have been cured by that problem. We have made some practical recommendations for prevention of working accidents and health protection for fishermen
Occupational Health
;
Accidents, Occupational
5.Trend of occupational lung disease in Viet Nam
Journal of Preventive Medicine 1998;8(3):65-70
Occupational lung disease (silicosis) in Viet Nam occupied the highest rate among occupational diseases and have an increasingly trend in a near future. The most important branches are coal mines, heavy industry, rock exploitation, construction, etc. Studies on prevalence and estimating the number of cases are important to set - up the prevention strategies for control and elimination of silicosis in Viet Nam.
Occupational Diseases
;
Silicosis
6.Study on actions of PDP (a nutritional substance) influencing on some physiological criteria in organism of experimental animals
Pharmaceutical Journal 1998;270(10):17-20
PDP extracted and modified from natural material was administrated by oral on chickens, white mice, white rats and rabbits. The effect of PDP on biological behavior, body weight, some organ weights such as liver, spleen, kidney and heart; rate between above organ weight and their body weight; histology of the organs, the studied animals was investigated. It was found that the biological behavior of the experimental animals has not been affected by DPD. No any change of central nervous activation or inhibition has been seen. The body weight, the weight of liver, spleen, kidney and the rate between them were not changed, too. Using PDP for long time with planned doses did not cause any toxic effect to the animals, even it also improved the resistance to disease when they were fed by PDP
Physiology
;
Animals
7.Study on the allergic potential and proliferative effect of Polysan cream used in the treatment of wound, burn on experimental animal
Pharmaceutical Journal 2000;285(1):11-13
Polysan cream has antibacterial effect, including gram negative one. It also has antifungal action, especially on Candida albicans. Polysan has a good homeostatic effect and high biocompatibility due to activation of newly generated cells. Polysan cream treated a lot of patients with partial and full-thickness burn wounds at National Institute of Burns, Saint Paul hospital in Hanoi and other hospitals in Vietnam. The good therapeutic efficacy was expressed in all cases. Both Polysaccharide material and Polysan cream have been licensed and patented by Vietnam Ministry of Health as the registrated material (R.Nr.NC1-HO1-98) and pharmaceutical product (R.Nr.NC2-HO1-98) respectively
Anti-Bacterial Agents
;
Antifungal Agents
8.Health promotion for workers in small and medium scale enterprises.
Journal of Preventive Medicine 2000;10(4):61-66
WHO and MOH collaborated to develop a pilot project on 'Health Promotion at Workplaces in SSEs and MSEs'. This project aimed to improve workers' health, helping them to protect health themselves increasing productivity and income; as a result it brings benefits to both enterprises and workers. This report presents the results that have been implemented in Hai Phong and Hue City and improvements of this model that can be applied in other places.
Health Promotion
;
Manpower
9.The prevalence of pulmonary silicosis among underground coal-mine workers in Quang Ninh province
Journal of Practical Medicine 2002;435(11):22-25
The prevalence of pulmonary silicosis was investigated among 387 randomly selected underground coal-mine workers. Out of these, 37 cases diagnosed with pulmonary silicosis (9.6%). Diggers appeared to be at higher risk of developing silicosis than others, with prevalence rate ratio of 3.3 (95% CI, 1.38 - 7.92). There was a significant relationship between length of exposure and risk of pulmonary silicosis (Chi square for trend, p = 0.001). Underground coal-mine workers with more than years of exposure were found to have increased rates of silicosis than those with less than years (prevalence rate ratio = 4.0) (95% CI: 1.88-8.53). The rate of silicosis among smokers was significantly higher than among non-smokers, prevalence rate ratio = 7.9 (95% CI: 3.7 - 17). Free silica content in the coal dust was found to be high (range from 11.2 to 39.2%). This study has highlighted the problem that free silica does exist in the coalmines of ViÖt Nam and the workers, especially the diggers, are at risk of developing pulmonary silicosis. More comprehensive medical surveillance should be carried out in the future with the participation of the different ministries and coal corporations
Silicosis
;
Prevalence
;
Lung Diseases
10.Study on synthesis of polymeric drug: Synthesis of antimalarial drug with delayed effect and natural origin
Pharmaceutical Journal 1999;282(10):9-11
The coupling procedure of antimalarial agent (SR2) onto polymeric carrier (SR1) by covalent bond (amide linkage) was studied. Some factors of drug coupling reaction was investigated.
Antimalarials
;
Pharmaceutical Preparations
;
drug therapy