1.Experience with an integrated seminar program on community medicine for high school students
Kazuhiro Yada ; Koh Abe ; Jin Kashima ; Tsuyoshi Noguchi ; Eishi Miyazaki ; Norio Shiraishi ; Takayuki Noguchi
Medical Education 2011;42(4):233-238
We held an integrated seminar program on community medicine for high school students. We used questionnaires to evaluate the usefulness of the seminar.
1)The seminar included lectures about community medicine, active–learning programs, and discussions about medical issues.
2)Before the seminar, 96% of the participants had been interested in a career in medicine.
3)After the seminar, 96% of participants were satisfied with the seminar.
4)The number of the participants who wanted to work in the community in Oita in the future increased from 43% before the seminar to 62% after the seminar.
Our results suggest that this integrated seminar program is useful for getting high school students interested in community medicine.
2.18F-FDG PET/CT for Diagnosis of Osteosclerotic and Osteolytic Vertebral Metastatic Lesions: Comparison with Bone Scintigraphy.
Kenzo UCHIDA ; Hideaki NAKAJIMA ; Tsuyoshi MIYAZAKI ; Tatsuro TSUCHIDA ; Takayuki HIRAI ; Daisuke SUGITA ; Shuji WATANABE ; Naoto TAKEURA ; Ai YOSHIDA ; Hidehiko OKAZAWA ; Hisatoshi BABA
Asian Spine Journal 2013;7(2):96-103
STUDY DESIGN: A retrospective study. PURPOSE: The aims of this study were to investigate the diagnostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in PET/computed tomography (CT) in the evaluation of spinal metastatic lesions. OVERVIEW OF LITERATURE: Recent studies described limitations regarding how many lesions with abnormal 18F-FDG PET findings in the bone show corresponding morphologic abnormalities. METHODS: The subjects for this retrospective study were 227 patients with primary malignant tumors, who were suspected of having spinal metastases. They underwent combined whole-body 18F-FDG PET/CT scanning for evaluation of known neoplasms in the whole spine. 99mTc-methylene diphosphonate bone scan was performed within 2 weeks following PET/CT examinations. The final diagnosis of spinal metastasis was established by histopathological examination regarding bone biopsy or magnetic resonance imaging (MRI) findings, and follow-up MRI, CT and 18F-FDG PET for extensively wide lesions with subsequent progression. RESULTS: From a total of 504 spinal lesions in 227 patients, 224 lesions showed discordant image findings. For 122 metastatic lesions with confirmed diagnosis, the sensitivity/specificity of bone scan and FDG PET were 84%/21% and 89%/76%, respectively. In 102 true-positive metastatic lesions, the bone scan depicted predominantly osteosclerotic changes in 36% and osteolytic changes in 19%. In 109 true-positive lesions of FDG PET, osteolytic changes were depicted predominantly in 38% while osteosclerotic changes were portrayed in 15%. CONCLUSIONS: 18F-FDG PET in PET/CT could be used as a substitute for bone scan in the evaluation of spinal metastasis, especially for patients with spinal osteolytic lesions on CT.
Biopsy
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Fluorodeoxyglucose F18
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Follow-Up Studies
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Humans
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Magnetic Resonance Imaging
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Neoplasm Metastasis
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Positron-Emission Tomography
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Positron-Emission Tomography and Computed Tomography
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Retrospective Studies
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Spine
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Technetium Tc 99m Medronate
3.Potential Applicability of Local Resection With Prophylactic Left Gastric Artery Basin Dissection for Early-Stage Gastric Cancer in the Upper Third of the Stomach
Yoshimasa AKASHI ; Koichi OGAWA ; Katsuji HISAKURA ; Tsuyoshi ENOMOTO ; Yusuke OHARA ; Yohei OWADA ; Shinji HASHIMOTO ; Kazuhiro TAKAHASHI ; Osamu SHIMOMURA ; Manami DOI ; Yoshihiro MIYAZAKI ; Kinji FURUYA ; Shoko MOUE ; Tatsuya ODA
Journal of Gastric Cancer 2022;22(3):184-196
Purpose:
Total or proximal gastrectomy of the upper-third early gastric cancer (u-EGC) often causes severe post-gastrectomy syndrome, suggesting that these procedures are extremely invasive for patients without pathologically positive lymph node (LN) metastasis. This study aimed to evaluate the clinical applicability of a stomach function-preserving surgery, local resection (LR), with prophylactic left gastric artery (LGA)-basin dissection (LGA-BD).
Materials and Methods:
The data of patients with u-EGC (pathologically diagnosed as T1) were retrospectively analyzed. Total gastrectomy was performed in 30 patients, proximal gastrectomy in 45, and subtotal gastrectomy in 6; the LN status was evaluated assuming that the patients had already underwent LR + LGA-BD. This procedure was considered feasible in patients without LN metastases or in patients with cancer in the LGA basin. The reproducibility of the results was also evaluated using an external validation dataset.
Results:
Of the 82 eligible patients, 79 (96.3%) were cured after undergoing LR + LGA-BD, 74 (90.2%) were pathologically negative for LN metastases, and 5 (6.1%) had LN metastases, but these findings were only observed in the LGA basin. Similarly, of the 406 eligible tumors in the validation dataset, 396 (97.5%) were potentially curative. Tumors in the lesser curvature, post-endoscopic resection status, and small tumors (<20 mm) were considered to be stronger indicators of LR + LGA-BD as all subpopulation cases met our feasibility criteria.
Conclusions
More than 95% of the patients with u-EGC might be eligible for LR + LGA-BD.This function-preserving procedure may contribute to the development of u-EGC without pathological LN metastases, especially for tumors located at the lesser curvature.