Of the patients with cerebral stroke admitted to the Saku Central Hospital from April 1972 to October 1977, we surveyed 60 people, aged 49 and under.
1) By type of disease, cerebral hemorrhage accounted for 40%, cerebral infarction 30%, and subarachnoid hemorrhage 30%. The prevalence of cerebral hemorrhage and subarachnoideal hemorrhage in this age group was higher than those in all ages.
2) Even in this age bracket, there were many with histories of hypertension and long periods of affection. The onset was observed among many of those who had not undergone or had discontinued treatment.
3) Abnormal ECG findings were observed in 35%.
4) Patients with a cardio-thoracic ratio of 51% and over in chest X-ray findings accounted for 64% of all patients.
5) Abnomally high hematocrit, serum and total cholesterol values were noted for few cases.
6) In respect to the prognosis of life and sequela, patients with cerebral infarction in this age bracket were better than those of all ages, but no statistically significant difference was observed between patients with ceberal hemorrhage in this age bracket and those in all ages.

BACKGROUND/AIMS: The objective of this study was to compare the clinical characteristics of patients with autoimmune pancreatitis (AIP) with or without Mikulicz's disease (MD) and with MD alone. METHODS: We investigated the clinical findings in 15 AIP patients with MD (group A+M), 49 AIP only patients (group A), and 14 MD only patients (group M). RESULTS: The male-female ratio was significantly higher in group A+M (73%, p<0.05) and group A (78%, p<0.01) than group M (21%). Serum immunoglobulin G (IgG) levels were significantly higher in group A+M than in group A (p<0.01) and group M (p<0.05). Serum IgG4 levels were significantly higher in group A+M than in group A (p<0.01). Other organ involvement was observed in 73% (11/15) of patients in group A+M. The number of patients with diabetes mellitus was significantly higher in group A+M (66%, p<0.01) and group A (51%, p<0.05) than in group M (7%). All of the patients responded well to steroid therapy, but the relapse rate in group A+M (33%) was significantly higher than that in group A (3%, p<0.01). Salivary gland function was impaired in all groups compared with the control group, but the degree of dysfunction was less in group A compared with group A+M and group M. CONCLUSIONS: The relapse rate of AIP in MD patients was significantly higher than that of AIP in patients without MD.
Diabetes Mellitus ; Humans ; Immunoglobulin G ; Mikulicz' Disease ; Pancreatitis ; Recurrence ; Salivary Glands