1. The body mass index, blood pressure and lipid status in the ischemic heart disease
Tsolmontsatsral B ; Tsolmon U ; Bayarchimeg B
Innovation 2014;8(2):34-38
According to the literature changes in the body mass index, blood pressure and lipid level might be the risk factors for the ischemic heart disease. The aim of this study was to investigate the BMI (body mass index), blood pressure, lipid levels in the blood of the participants.The BMI and blood pressure were measured by World health organization’s standard methods. Low and high density lipoproteins(LDL, HDL), triglyceride, cholesterol, c reactive protein level were examined from the blood.The BMI of the case group was 26.3(±6) kg/m2, whereas in control group it was 24.8(±3.76) kg/m2. Lipid status was almost same between case group and control group. Also both groups was higher than normal level. The case group of 41.6% and control group of 17.3% are increased by all status triglyceride. The triglyceride level of the patients was 2.1(±2)mmol/l and 1.32(±0.88) mmol/l in control group. HDL level was 56.7(±16.38) in the case group and 50.4(±25.1) in control group. Almost same percentage of bough groups (39-40%) showed decreased level of HDL. 36% of ischemic patients and 40% of control group showed increased cholesterol level. The percentage of people ≥30 kg/m2 was significantly higher (p<0.05) in the case group. There were no significant difference in blood pressure, LDL, HDL and c reactive protein level between the groups. The triglyceride level in case group was significantly higher (p<0.05) than in control group.
2.Therapeutic effect of Medicinal leech /Hirudo medicinalis/ on blood lipid and coagulation
Uyanga Ts ; Bilegt B ; Tsolmon U ; Gurbadam A
Innovation 2016;10(3):20-23
Medicinal leech /Hirudo medicinalis/ secretes 150 over bioactive substances from savilary gland, which are hirudin, hialuronidasa, bdellin, eglin, destabilasa, lipase, cholesterol esterase. Medicinal leech’s therapeutic effect is anticoagulant, antiplatelet, anti-ischemic, hypotensive, anti-inflammatory, anti-atherosclerotic and thrombolytic. In Mongolia, medicinal leech therapy’s research is rare.
The study was designed as selective sampling and clinical trial study. From June 1st between September 1st in 2016, there were enrolled 30 patients with diagnosis of arterial hypertension stage I at “Piyavka” hospital in Hentii province. Patients were used by method of Medicinal leech therapeutic of the Russian Federation in 2011. Blood samples were used SD LipidoCare analyser, Stago Compact automatic coagulation analyzer. Fibrinogen, Activated partial thromboplastin time, Thrombin time, Prothrombin time, International normalized ratio and Blood lipids level were checked before and after treatment.
A total of 30 patients were enrolled in the study. 16 were females, 14 were males and the mean age was 59.13±11.62. Activated partial thromboplastin time was before 37.97 ±5.62 sec and after 45.94±6.05 sec therapy of leeches. Thrombin time was before 17.59 ±1.66 sec and after 19.53±1.38 sec therapy of leeches. As patients who was increased from normal lipid level in blood before leech therapy, Total cholesterol was before 220.63±14.51 mg/dl, after 204.63±13.64 mg/ dl therapy of leeches. Triglyceride level was before 253.69±71.99 mg/dl, after 184.12±61.73 mg/ dl therapy of leeches.
Mean of Activated partial thromboplastin time, Thrombin time were prolonged with statistically significant after treatment (p=0.0001). As patients who was increased from normal lipid level in blood before leech therapy, Total cholesterol (p=0.031), Triglyceride (p=0.0003) were decreased with statistically significant by therapy of leeches.
3.Sensitivity and specificity of romhilt-estes score criteria for detecting left ventricular hypertrophy
Mongolian Medical Sciences 2013;164(2):34-37
BackgroundLeft ventricular hypertrophy (LVH) is associated with a substantially increased risk of cardiac morbidity and mortality [1-4], so its detection is of major importance, especially for individuals with hypertension or other cardiovascular risk factors. There are many criteria for the diagnosis of left ventricular hypertrophy based on the electrocardiogram but specificity and sensitivity are different depending on age, sex, obesity and ethnicity.GoalThe present study was conducted to determine the sensitivity and specificity of Romhilt-Estes point score criteria of ECG for the assessment of left ventricular hypertrophy by comparing it with the gold standard of echocardiography.Materials and Methods154 clinically diagnosed patients with primary arterial hypertension were included in this study. ECG of the patients was recorded and Romhilt-Estes score criteria calculated. This was followed by echocardiography and left ventricular mass and left ventricular mass index was calculated.ResultsIt was found that Romhilt-Estes score criteria had a sensitivity of 34.9% and specificity of 96.7%. The positive predictive value was 97.73 %whereas negative predictive value was 27.27 %.ConclusionsSensitivity of the criterion Romhilt-Estes score criteria was relatively poor for the diagnosis of left ventricular hypertrophy in patients with arterial hypertension. But specificity of Romhilt-Estes score criteria was high.
4.Prevalence of uncontrolled hypertension and it’s influencing factors
Baigalmaa L ; Nandintsetseg B ; Buyndelger B ; Tsolmon U
Mongolian Medical Sciences 2011;172(2):65-69
Introduction: According to the report of World Health Organization and International Society of Hypertension, an estimated 17.5 million people died from cardiovascular diseases in 2005 representing 30% of all global deaths, 1.5 billion people had hypertension and 45% of hypertensive people were unaware of their condition in 2007. In our country, prevalence of hypertension and its risk factors are studied, but prevalence of uncontrolled hypertension that is an important criterion of hypertension control, and its influencing factors is not reported yet. Goal: The aim of our study is to evaluate prevalence of uncontrolled hypertension and to determine its some influencing factors.Materials and Methods: It was population based, cross sectional, prospective study. Participants of the study were selected by randomized method. In the study, 1111 individuals that live in Bayanzurkh and Songinokhairkhan districts of Ulaanbaatar city are participated. The study based on questionnaire and BP measurement which aimed to reveal:• Hypertension unawareness• Untreated• Treated and uncontrolledStatistical analysis was performed by using SPSS 17.0 program.Results: In the study, in total 1111 people aged ≥18 years have been involved. Mean age of all participant was 40.58±16.10 and 63.2% of them were female. We estimated that 38.4% of the population had hypertension and 28.3% of those were unaware their hypertension (unawareness). Among aware population, untreated population percent were 42.1%. We determined that age, sex, education level and visiting to physicians can be risk factors of uncontrolled hypertension.Conclusion: Of the estimated 1111 people with hypertension 28.3% were unaware of their hypertension, 29.5% were aware of their condition but were not being treated, 33.7% were being treated but their hypertension remained uncontrolled and only 8.4% were taking medications that controlled their hypertension. Factors such as young age, male gender, and not measuring BP for the last one year influence negatively on uncontrolled hypertension (p<0.005).
5. THE FEATURES OF CAREER CHOICE IN HIGH SCHOOL STUDENTS
Bolormaa B ; Oyunsuren B ; Altangerel CH ; Tsolmon CH
Innovation 2015;9(3):156-159
A child’s career aspirations are based on a number of external factors such as ethnicity, gender, age, income, family influence and socioeconomic status. These factors are interrelated and given varying degrees of importance culturally, for example, in the UK, white British parents tend to have high aspirations for their daughters whereas, in Pakistani and Bangladeshi families, daughters are expected to marry, not excel in their education or career. High school students of secondary education in terms of gender, 34432 studentsenrolled in high school who are studying in 46.47% of men and women are 53.52% of the high school, there are changes in the gender disparity. This study is conducted due to Millennium Development Goal 3 is to eliminate gender disparity in education by 2015. This study was conducted among General Education School students of Ulaanbaatar city in 2015. Three hundred twenty four school students participated in this study. The cross sectional study was conducted with 294 high school students.Thirty high school students participated in focus group interview. This study was used qualitative and quantities design.Of the respondents, 47.6% were male and 52.4% female. 79.3% of high school students have chosen a career and 20.7% of high school students have not chosen yet. We are evaluated in career choice with a focus on a gender issue. P = 0.0001 whether there are statistically significant and career choice have different in men and women gender.In this study, 20.7 percent of high school students do not choose career due to a lack of information,do not give the professional advice from the school for them. Thus, schools need to introduce if possible considering the foreign experience, lesson of career choice is reflected in the school curriculum.
6. THE WEIGHT OF SCHOOLBAGS AND MUSCULOSKELETAL SYMPTOMS IN SCHOOL STUDENTS, ULAANBAATAR, MONGOLIA
Oyunsuren B ; Bolormaa B ; Naransukh D ; Tsolmon CH
Innovation 2015;9(3):184-188
There is a little information about weight excess of school materials in Ulaanbaatar, Mongolia. The aim of this study was to study of the weight of backback and the ergonomic effects of backpack carriage on school students in Ulaanbaatar. This cross-sectional study was performed in the city of Ulaanbaatar in 2015. Two hundred fourteen school students participated in study. Nordic Musculoskeletal Questionnaire was used, asking about complaints of neck, shoulders, upper and lower back. Length and weight of the children were determined. Backpacks were weighed and the relative weight of the backpack was calculated.In this study, first and second grades students carried proportionately heavier backpacks than older students and more than 10% of their weight. Musculoskeletal complaints were reported by about 79% of school students. The (relative) weight of backpacks was not related to complaints of neck, shoulders, upper and lower back.
7.Oral health status of patients with cardiovascular diseases
Tsolmontsatsral B ; Unenchimeg S ; Tsolmon U ; Bayarchimeg B
Mongolian Medical Sciences 2013;163(1):117-121
IntroductionChronic periodontitis has been associated with cardiovascular diseases (CVD).GoalThe goal of the present study was to investigate the periodontal status of patients with ischemic heart diseases.Materials and ÌethodsWe studied 35 subjects with clinically newly confirmed ischemic heart disease and 64 matched control subjects with no evidence of cardiovascular diseases all receiving a comprehensive periodontal examination.ResultsPatients with ischemic heart disease had significantly lower numbers of natural teeth. The percentage of participants with periodontal pockets (p<0.001) and clinical attachment losses (p<0.001) were higher in the case group. Statistical analysis demonstrated a difference in the proportion of sites with a periodontal probing depth >3.0 mm (26% for case and 3% for control group, p<0.001). The mean periodontal pocket depth was 5.29 mm in the case subjects and 3.3 mm in the control group.ConclusionOur findings suggest that patients who at routine dental visits demonstrate evidence of deep periodontal pockets and clinical attachment losses around several teeth can predictably be identified as being at risk of future cardiovascular diseases, especially ischemic heart disease. Such subjects should be referred for medical and periodontal examinations and treatments.
8.The current situation of the early detection and control of hypertension and its strategy
Nandintsetseg B ; Baigalmaa L ; Tsolmon U ; Serjee D ; Zolzaya B ; Angarmurun N
Mongolian Medical Sciences 2010;153(3):6-11
Background According to the report of World Congress of Cardiology in 2007, 1.5 billion people had hypertension and 45% of hypertensive people were unaware of their condition. In our country, some study had provided estimation of risk factors and prevalence of hypertension, but main characteristics presenting the early detection and control of hypertension have not been studied well and information does not exist.The quality of the control, registration and early detection of hypertension will be improved by studying this topic and complications and mortality due to the hypertension could be decreased.GoalThe aim of our study is to evaluate the current situation of the early detection, registration and control of hypertension, and to describe future strategyObjectives:1. To describe the hypertension awareness and risk factors associated with early detection of hypertension2. To evaluate the current situation of registration system of hypertension and to find out the strategies for renewing registration system3. To investigate the rates of the treatment and control of hypertension, and to survey factors associated with the control of hypertensionMaterials and MethodIt was population based, cross sectional, prospective study. Participants of the study were selected by randomized method.In the study, 1103 individuals, 133 physicians and 2 family hospitals located in Bayanzurkh, Songinokhairkhan districts, were surveyed. The study based on questionnaire and BP measurement which aimed to reveal:• Hypertension awareness (%)• Treatment (%)• Control (%)Software program name: Arterial hypertension registration and control Objectives of the program: to evaluate registration of arterial hypertension, to detect earlier, to determine control level of hypertension Users: family hospitals, family doctorsType of morbidity registration: population basedStatistical analysis was performed with SPSS-17 software program. Single- and multi-factorial analysis was explored by using simple and logistic regression and significance.ResultsIn the study, in total, 1103 people aged of ≥18 years living in Bayanzurkh and Songinokharkhan districts of Ulaanbaatar, have been involved. 37% of all participants were male and 63% were female and mean age of all participants was 40.6±16.1. According to our study, 305 individuals of 431 hypertensive participants (70.8%) were aware of their hypertension. This result was different in gender: 58.0% in male, 79.0% in female. Our research team created software program that can integrate all hypertension data to one database. We are planning to determine unawereness; aware and treated; treated and controlled; and uncontrolled levels by using this software and to introduce the program created by us to all primary level physicians in order to use routinely.Conclusions:1. Among hypertensive individuals, awareness of hypertension was 70.8%. Factors such as young age (<35), single people and not measuring BP for the last one year influence negatively on early detection of hypertension (p<0.05).2. Current method of hypertension registration is not proper at the time. Therefore, we concluded that renewing of the arterial hypertension registration database and conversion it into electronic type is convenient to control arterial hypertension and to provide integration.3. Treatment level of arterial hypertension was 39.9%, controlled arterial hypertension among all hypertensive population - 10.2% and among treated population – 25.2%.
9. Therapeutic effect of Medicinal leech /Hirudo medicinalis/ on blood lipid and coagulation
Uyanga TS ; Bilegt B ; Tsolmon U ; Gurbadam A
Innovation 2016;10(3):20-23
Medicinal leech /Hirudo medicinalis/ secretes 150 over bioactive substances from savilary gland, which are hirudin, hialuronidasa, bdellin, eglin, destabilasa, lipase, cholesterol esterase. Medicinal leech’s therapeutic effect is anticoagulant, antiplatelet, anti-ischemic, hypotensive, anti-inflammatory, anti-atherosclerotic and thrombolytic. In Mongolia, medicinal leech therapy’s research is rare.The study was designed as selective sampling and clinical trial study. From June 1st between September 1st in 2016, there were enrolled 30 patients with diagnosis of arterial hypertension stage I at “Piyavka” hospital in Hentii province. Patients were used by method of Medicinal leech therapeutic of the Russian Federation in 2011. Blood samples were used SD LipidoCare analyser, Stago Compact automatic coagulation analyzer. Fibrinogen, Activated partial thromboplastin time, Thrombin time, Prothrombin time, International normalized ratio and Blood lipids level were checked before and after treatment. A total of 30 patients were enrolled in the study. 16 were females, 14 were males and the mean age was 59.13±11.62. Activated partial thromboplastin time was before 37.97 ±5.62 sec and after 45.94±6.05 sec therapy of leeches. Thrombin time was before 17.59 ±1.66 sec and after 19.53±1.38 sec therapy of leeches. As patients who was increased from normal lipid level in blood before leech therapy, Total cholesterol was before 220.63±14.51 mg/dl, after 204.63±13.64 mg/ dl therapy of leeches. Triglyceride level was before 253.69±71.99 mg/dl, after 184.12±61.73 mg/ dl therapy of leeches. Mean of Activated partial thromboplastin time, Thrombin time were prolonged with statistically significant after treatment (p=0.0001). As patients who was increased from normal lipid level in blood before leech therapy, Total cholesterol (p=0.031), Triglyceride (p=0.0003) were decreased with statistically significant by therapy of leeches.
10.Current management of myocardial infarction treated at the state second central hospital
Tsolmon U ; Dolgormaa P ; Selenge B
Mongolian Medical Sciences 2015;172(2):55-59
AimThe aim was to study retrospectively the possible changes in practice patterns in the managementof patients with acute myocardial infarction who were admitted to the State Second Central Hospitalduring the last 5 years.Material and MethodThis study conducted at the State Second Central Hospital in September 2014.Patients with acute myocardial infarction were divided into 2 groups: main and control. Main groupincluded 95 patients with myocardial infarction who were treated from 2010 to July 2014. Controlgroup included 102 patients with myocardial infarction who were treated from 2005 to 2009.From 2005 to 2012 patients fulfilled the diagnostic criteria of myocardial infarction based on WHOcriteria. From 2013 to 2014 patients fulfilled the diagnostic criteria of myocardial infarction based onnational guideline’s criteria. Differences in proportions in the groups were tested with the chi squaretest. P value of <0.05 was considered significant.ResultsA total 197 patients (mean age 71.2±6.1, 62% man, and 38% women) with acute myocardial infarctionwere enrolled. More than half had a history of arterial hypertension. Atypical forms of myocardialinfarction increased from 25.8% in 2005-2009 to 40.4% in 2010-2014. ST elevation myocardialinfarction and non ST elevation myocardial infarction were detected in 61% and 39% of patientstreated in 2010-2014. Diagnostic use of troponin was increased significantly in last 5 year (44.2% vs.88.6%, p<0.05).The study revealed only 17.2% of patients with acute myocardial infarction met the national guidelinesgoal of pre-hospital time <12 hours. Eighty four (88.3%) patients of the main group received medicaltherapy and 11(11.7%) treated with percutaneous coronary intervention. Aspirin was prescribed in80.7% of main group, heparin in 97.9%, ACE inhibitors in 47.9%, Beta blocker in 14.9% within 24hours of acute myocardial infarction.ConclusionsCompared with control group use of troponin and invasive treatment strategy has increased since2010 in the management of patients with acute myocardial infarction. Delay of pre-hospital timeremains an actual problem in the management of acute myocardial infarction.