1.Results of screening for cytomegalovirus infection among blood donors in Ulaanbaatar, Mongolia
Tsogbadrakh B ; Naranchimeg L ; Erdenebayar N ; Munkhbayarlakh S
Mongolian Medical Sciences 2015;172(2):7-9
Background. Most people infected with Cytomegalovirus (CMV) have no signs or symptoms, but newborns andpeople with weakened immune systems are more at risk of developing signs and symptoms. CMV remains in thebody throughout a lifetime. Infected people may spread infection.Goal. The main aim of this study is to determine the prevalence of infection of cytomegalovirus (CMV) by enzymeimmunosorbent assay.Materials and Methods. In this study included subjects, age range of 17-60 years (total of 716) blood donorswho were served by the National center for transfusion medicine. Screening for Cytomegalovirus CMV IgG andIgM specific antibody concentrations determined using DIALAB ELIZA kits.Results. CMV-specific IgG antibodies were detected in 99.2% (710) of the studied subjects and, specific IgMantibodies in 0.1% (1). IgG antibodies positive individuals are compared to 4 blood groups and (p = 0.01) differencewas not statistically significant. IgG antibodies negative 6 individuals are included all in blood type B(III). IgMspecific antibodies positive (1) individual was in the age group 26-40 years, female and type of regular donor.Conclusion. We can conclude from our results of the determination of CMV IgG and IgM specific antibodiesshows that a number of risks of transfusion transmitted infection cytomegalovirus.
2.Geographical Distribution of Tick Borne Encephalitis in Mongolia
Uyanga B ; Uranshagai N ; Burmaajav B ; Undraa B ; Tserennorov D ; Tsogbadrakh N
Mongolian Medical Sciences 2020;191(1):50-56
Background:
Medical geography deals with the application of major concepts and theories derived from human and
physical geography to issues of health and disease. Between1970-1980, Russian scientists were first
figured landscape, geographical distribution of TBE in Mongolia. Since human cases of TBD were
registered from 2005, around 2000 cases of TBD were registered. From 15% of diseases and 78%
of fatal cases were tick-borne encephalitis. Therefore, were tried to create current geographical
distribution of TBE in Mongolia and detect risk areas.
Мaterials and Methods:
287 TBE cases data, information of TBE positive tick and human data were analyzed which registered
in NCZD between 2005-2017. Arc GIS 9 were used for create map. Mongolian map was divided by 5
landscape range such as forest-taiga, forest-steppe, steppe, steppe-desert, gobi and high mountain.
Result:
In forest-taiga range, 57% of TBE cases and incidence was 9.51 per 10000 population. 56.4%
of I.persulcatus tick, 1.9% of D.nuttalli tick were found and infection rate of tick was Ixodes
persulcatus-6.97%, Dermacentor nuttalli-5.2%. Seroprevalence of TBE was 25±12.1 among
population.
In forest-steppe range, 40% of TBE cases and incidence was 0.56 per 10000 population. 43.6% of
I.persulcatus tick, 44.3% of D.nuttalli, 24.4% of D.silvarum tick tick were found and infection rate of
tick was Ixodes persulcatus-3.08%, D.silvarum-1.56% and D.nuttalli-1.56%. Seroprevalence of TBE
was 14.5±11 among population.
In steppe range, 0.7% of TBE cases and incidence was 0.12 per 10000 population. 62.2% of
D.silvarum tick, 23.9% of D.nuttalli tick were found and infection rate of tick was D.nuttalli-2.81% and
D.silvarum-1.2%. Seroprevalence of TBE was 16.3±6.5 among population.
In other range including steppe-desert, gobi and high mountain, 2.8% of TBE cases and incidence
was 0.1-0.27 per 10000 population. 62.2% of D.silvarum tick, 47.6% of D.nuttalli tick were found and
infection rate of tick was D.nuttalli-0.84%. Seroprevalence of TBE was 2.5-13.1 among population.
Conclusion
Natural foci of tick-borne encephalitis have been registered in all landscape ranges of Mongolia and
higher risk area of those ranges were forest-taiga and forest-steppe.
Dermacentor silvarum, Dermacentor nuttalli tick becoming dominant vector of TBE in steppe range.