1.Identifying relation of anxiety and salivary cortisol among abused children
Altanzul Kh ; Munkhtulga G ; Tsend-Ayush A ; Oyunbileg O ; Jargal B ; Odkhuu E ; Khishigsuren Z
Innovation 2013;7(2):44-48
WHO informed that across world an average of 565 young people aged 10 to 29 die every day through interpersonal violence. Some studies mentioned that anxiety was most frequently occurred as one of the psychological consequences among victims of child abuse. Recent research on effects of adverse early life experiences on central nervous system as stress systems (hypothalamus-pituitary-adrenal axis-HPA) has provided a greater understanding of the link between childhood abuse and susceptibility to anxiety disorder. Therefore, this research was done to study anxiety among abused adolescents, some physical parameters and level of cortisol in saliva.
There were selected 20 abused children and 40 non abused children aged between 11-16 years old and lived in Ulaanbaatar city. The Spence Children’s Anxiety Scale (SCAS; Spence, 1997) is a 38-item self-report questionnaire that assesses multiple symptoms of childhood anxiety disorders based on current diagnostic criteria. All participants were measured the cortisol in the saliva by Cortisol ELISA kit, Sigma,
Average age of all subjects in the study was 13.52±1.57 and 59% of them were female and 41% were male. All anxiety symptoms of case group was statistically significance higher (p<0.01) than control group. The average amount of salivary cortisol of case group was (18.65±7.08) statistically significantly lower (p<0.01) than average amount of control group (32.15±20.99).
Anxiety was more frequently occurred among abused children and blunted cortisol responses might indicate a level of impaired HPA functioning that could constitute a vulnerability to psychopathology with exposure to anxiety.
2. Identifying relation of anxiety and salivary cortisol among abused children
Altanzul KH ; Munkhtulga G ; Tsend-Ayush A ; Oyunbileg O ; Jargal B ; Odkhuu E ; Khishigsuren Z
Innovation 2013;7(2):44-48
WHO informed that across world an average of 565 young people aged 10 to 29 die every day through interpersonal violence. Some studies mentioned that anxiety was most frequently occurred as one of the psychological consequences among victims of child abuse. Recent research on effects of adverse early life experiences on central nervous system as stress systems (hypothalamus-pituitary-adrenal axis-HPA) has provided a greater understanding of the link between childhood abuse and susceptibility to anxiety disorder. Therefore, this research was done to study anxiety among abused adolescents, some physical parameters and level of cortisol in saliva.There were selected 20 abused children and 40 non abused children aged between 11-16 years old and lived in Ulaanbaatar city. The Spence Children’s Anxiety Scale (SCAS; Spence, 1997) is a 38-item self-report questionnaire that assesses multiple symptoms of childhood anxiety disorders based on current diagnostic criteria. All participants were measured the cortisol in the saliva by Cortisol ELISA kit, Sigma, Average age of all subjects in the study was 13.52±1.57 and 59% of them were female and 41% were male. All anxiety symptoms of case group was statistically significance higher (p<0.01) than control group. The average amount of salivary cortisol of case group was (18.65±7.08) statistically significantly lower (p<0.01) than average amount of control group (32.15±20.99).Anxiety was more frequently occurred among abused children and blunted cortisol responses might indicate a level of impaired HPA functioning that could constitute a vulnerability to psychopathology with exposure to anxiety.
3.Some aspects of traditional Mongolian medicine research
Purevjav M ; Ariunaa Z ; Chimedsuren O ; Tsend-Ayush D ; Burmaajav B
Mongolian Medical Sciences 2014;168(2):61-66
BackgroundTraditional Mongolian Medicine has a history of over 5000 years. Scientific development of TM hasstarted in 1959. Since 1999 Mongolia was categorized by WHO as a country having an Integrativesystem of TM- officially recognized and incorporated into all areas of health care provision, TMMresearch has been following key objectives of National R&D programs.AimIn order to assess the situation of TMM development we have conducted this study based on last10 years’ research done.Ìaterial and MethodsDocument study- we have selected key TMM’s R&D project implementers’ archive and humanresources documents.Descriptive and Analytic methods- a survey of 32 questions evaluating participation of TMMprofessionals in R&D work were conducted. Also, to clarify the point of view about TMM’s R&D6 focus group meetings with different level participants, such as professional committee, policymakers and research workers as well as health care providers, were organized.ResultsFrom 2004-2013, there are 28 projects implemented on TMM, 43% accomplished by TMMRTC,32.8% of which is resulting in raw materials standardization and technology study, related clinicalstudies standing 20% out of all studies done on TMM matter. These numbers are confirmed bysurvey and focus group interviews, more than 50% of participants willing to conduct a clinical studyand expressing difficulties such as lack of knowledge of methodology, policy support and revenue.Conclusions:1. TMM R&D has a potential growth due to human resources capacity. Practitioners are leastinvolved in R&D, due to lack of knowledge of methodology and revenue.2. There were 28 projects implemented on TMM matter, most of these are basic studies, fewerclinical studies done, resulting in pharmacopeia monographs and technological guidelines.
4.RESULT OF DISABILITY STATUS STUDY AMONG POPULATION
Tsend B ; Tserenbat M ; Naransukh D
Innovation 2017;11(2):81-84
BACKGROUND. Tn 2016, determination on the extent of disability degree, assessment
of further allowance terms of people were 5.1% of total population nationwide and
most of them commission of disability assessment and hospital-labor identification determined
cause of disabilities such as ordinary disorders, home and industrial accidents,
profession related diseases and Social Insurance and Social Welfare fund grants disability
pension. Total budget for these pensions were 158.9-252.4 billion MNT during last
5 years and it was 1.6 fold increased if compared to previous years. For nationwide
consideration of disability by percent, 41% of total disabled people completely disabled
and 59% of them incompletely disabled. There is a need to improve regulatory
framework and suitable job employment for disabled people, rehabilitation for affected
organ systems and treatment of insured people and others illnesses to get healthy.
PURPOSE: To study extent of disability degree among population of Songinokhairkhan
district during last 5 years. MATERIALS AND METHODS: We performed document analyzing
method. For statistical analyzes we used data analyzing software Stata 22.0. RESULTS:
For percentage of disability among population of Songinokhairkhan district during last 5
years showed 3.20% in 2012, 3.22% in 2013, 3.60% in 2014, 3.85% in 2015 and 3.66% in 2016
respectively. By gender status, dominantly males were affected or 2.85% of total population
and females were 1.98% affected in average status of last 5 years. By education
level, there were mainly secondary or uneducated people. By social and employment
status, unemployed people dominantly affected. CONCLUSION: There is a tendency
that may increase criteria in study of disability prevalence, circumstance and etiology
during last 5 years. Average of last 5 years, extent on disability degree and assessment
of further allowance terms of newly determination was 6.5% and people who extended
their terms were 79.5% and 14% of them cancelled. Total amount of money spent for
disabled people during last 5 years was 18.8 billion which increased by 55% from previous
budget of 8.29 billion.
5.Histopathological and immunohistochemical characteristic for lung cancer among Mongolian patients
Tsend-Ayush B ; Anarkhuu B ; Nyamjargal B ; Uranchimeg B ; Bayarmaa E ; Saymaa L
Innovation 2021;15(1):4-11
Background:
Lung cancer is the leading cause of cancer death in both men and women.
In the past decade, histopathological classification of lung cancer has become increasingly
important in selecting the appropriate treatment.
Methods:
All cases of lung cancer diagnosed pathologically in the last 2.5-year period were
retrospectively identified at National Cancer Center and performed by descriptive case series
design.
Results:
The average age of our participants was 62, of which 82.2% were men. A total of 214
cases of lung cancer were reported, including 142 (66.4%) squamous cell carcinoma (SCC),
34 (16%) adenocarcinoma (AC), 4 (1.7%) NSCLC, 29 (13.6%) small cell carcinoma (SmCC) and
5 (2.3%) cases of other/unspecified type. Based on only morphology, initially 32 (17.7%) cases
of NSCLC were diagnosed, whereas after immunohistochemistry (TTF-1 or NAPA positive/p63
negative, and vice versa) staining, this category reduced to 2.2%.
Conclusions
Among both males and females, SCC which is highly related to smoking was
the most common histologic type of lung cancer. Our results showed that an approach of using
only a two-antibody panel (p63 and TTF-1) might help in the reduction of diagnostic category of
NSCLC-NOS significantly.
6.Saposhnikovia Divaricata (Turcz.) Schischk.): A review of its phytochemistry and pharmacology
Akhsholpan B ; Tsend-Ayush P ; Saikhanbayar P ; Davaasambuu T ; Oyunchimeg S ; Lkhagva L ; Tsetsegmaa S ; Khurelbaatar L ; Lkaasuren R
Mongolian Pharmacy and Pharmacology 2022;20(1):30-38
Abstract
Saposhnikovia divaricata, a perennial herb belonging to the family Umbelliferae, is widely distributed in many provinces of Mongolia. The dried root of Saposhnikovia divaricata has been used for the treatment of arthritis and as a painkiller in Mongolian folk medicine. Moreover,
its dried root (Radix Saposhnikoviae) is used as a Chinese herbal medicine for the therapy of immune system, nervous system, and respiratory diseases. According to phytochemical and pharmacological studies, the main ingredients of Saposhnikovia divaricata are chromones, coumarins, acid esters, and polyacetylenes. These compounds indicate anti-inflammatory, antioxidant, analgesic, antiproliferative, and immunoregulatory activities. Cimifugin is an active ketone ingredient from Saposhnikovia divaricate, Rhizoma cimicifugae. Cimifugin has been reported to have bacteriostatic and antiviral effects. Studies have reported that cimifugin inhibits allergic inflammation by reducing the levels of cytokines. The aim of this review is to provide extensive information on the traditional use, ethnopharmacology, phytochemistry, pharmacology mechanism of action, and health products from Saposhnikovia divaricata .