Xeroderma pigmentosum is a genodermatosis characterized by extreme sun sensitivity, photophobia, freckly hyperpigmentation, atrophy, telangiectases, keratoses and finally malignant degeneration of the skin. It is rare and prebobly inherrited as a recessive trait, Photosensitive cutaneous symptoms developed in complication with squamous cell ca is presented. A 20-year-old male were studied. Routine laboratory examinations were within normal limits including hemogram, urinalysis, blood urea nitrogen, serum creatinina, liver function tests(including bromsulphalaein excretion) and serum electrolytes, chest X-Ray. The histopathological picture showed characteristic xeroderma pigmentosum and squamous cell ca. Clinical, histopathological and biochemical features of this disease are also discuseed.
Atrophy ; Blood Urea Nitrogen ; Electrolytes ; Humans ; Hyperpigmentation ; Ichthyosis* ; Keratosis ; Liver ; Male ; Photophobia ; Skin ; Solar System ; Telangiectasis ; Thorax ; Urinalysis ; Xeroderma Pigmentosum* ; Young Adult