The concentration of TSH receptor autoantibodies (TRAB) was determined by a Radioreceptor assay kit (RRA) in human serum of normal subjects and Basedow’s patients before and after treatment with antihydroid druf (ATD). The results were as following: Mean TRAB level in Basedow’s patients is higher than that in normal subjects (323.75+/-171.27u/l vs. 1.36+/-0.57u/l). There was not significant difference in the concentration between men and women in both groups. After treatment, the TRAB level was decreased to 10.63+/-11.16u/l.
Graves Disease ; Autoantibodies ; Thyrotropin

The human thyroglobulin (hTG) level was quantified in 31 serum samples taken from healthy people who aged from 18-55 years old. The standard curve, accuracy of technique and the serum hTG level of healthy people was determined. The results showed that the hTG quantified technique using immunoradiometric assay (IRMA) kits of CIS Bio International provided high accuracy. The average serum hTG level of healthy people is 7.35+/-6.99ng/ml; with common rage is 0.00 to 2ng/ml.
Thyroglobulin ; Immunoradiometric Assay

Using the radioimmuno assay to quantify the serum concentrations thyroglobulin and calcitonin in the normal people and patients with the thyroid cancer to evaluate the relation between them and apply this technique for diagnosing the cancer. The comparison found that the serum calcitonin in the patients with the thyroid cancer was lower than this in normal people during the severe or treated phase of the disease. The serum calcitonin concentration was only applied in the phase that the thyroid cells has not been destroyed, phase of relapse or remote metastasis.
Thyroid Neoplasms ; Radioimmunoassay

The serum concentrations of tumor markers of hTG and hCT in 33 healthy people were determined by the immunoradiometry assay (IRMA) has shown that the concentration of hTG and hCT was 7.35 +/- 6.99 mg/ml 5.74 +/-5.92ng/ml, respectively. There was no difference of concentrations of hCT and hTG between men and women.
Thyroid Neoplasms ; Immunoradiometric Assay

The quantification of markers of breast cancer in healthy people (26 people for CA 15-3 and 28 people for CEA) by IRMA has shown that the serum concentration of CA15-3 and CEA was 19.12+/- 15.44 u/ml and 4.19 +/- 2.35 ng/ml, respectively. The medium (4.48), mininum (0.00) and maxinum (8.37) ng/ml. These results can be used to compared with markers in patients with breast cancer. There was no difference of these between men and women.
Breast Neoplasms ; breast

The quantitative analysis of the concentration of serum calcitonin was carried out in 29 normal people with ages of 18-50. The results: this is a method with the high confidence; the average concentration of serum calcitonin is 5,74 Pg/ml; the minimal concentration at 0,00 commonly found, the maximal concentration is 22,6 Pg/ml; the distribution was not same as the rule of Gauss so the medial figure was 4,98pg/ml as preparesentative; there is no different of this concentration between male and female.
calcitonin ; serum

Serum levels of tumor maker CA 19-9 were quantified in healthy young and middle adults, including both genders. Participants had to have no sign of tumor or inflammatory diseases. Technically, level of CA 19-9 as quantifying by IRMA kid of CISbio International was reliable with%CV ranged from 0.1 to 5.4. Average value of CA 19-9 is 17.11+/-11.06. Level in high area was no more than 35.7 U/mL. Upper and lower marginal areas were 26.61 U/mL and 5.68 U/mL, respectively. There was no significant difference between two genders
Immunoradiometric Assay ; Serum

The quantification of CA 72-4 and CA 19-9 in normal people and patients with the peptic cancer was analysed and evalutated in the clinical application. The conentration of CA 72-4 and 19-9 in the normal people (disease free, tumor and infection free) and patients with the pepsic cancer (diagnosed by pathological anatomy and cytology) were quantified an compared.
Immunoradiometric Assay ; Peptic Ulcer ; neoplasms

A study was carried out to apply the IRMA to quantity the CA15-3 in the normal person and CA15-3 and CEA in the patients with the breast cancer. The clinical efficacy of CA15-3 and CEA were also evaluated. The subjects were normal people without tumor, chronic diseases, infection, inflamatory, hepatic diseases and the patients with the breast cancer who received the pathological anatomy and cytology.
Breast Neoplasms ; diagnosis ; Immunoradiometric Assay ; neoplasms ; breast

The quantitative analysis of the concentration tumor marker CA15-3 by the immunoradioactive method in the serum of 26 normal persons without the tumor, hepatic diseases and chronic diseases ages of 18-50 has shown that this is method with high accuracy. The radioactive activity is direct proportional with the concentration of CA 15-3; The concentration of CA 15-3 in the normal people is 19,12+/-15,54 u/ml in which 90% persons have concentration under 30% u/ml. The concentration of CA 15-3 is most common in 4,71 u/ml.
Tumor Markers, Biological ; Chronic Disease