The quantitative analysis of the concentration tumor marker CA15-3 by the immunoradioactive method in the serum of 26 normal persons without the tumor, hepatic diseases and chronic diseases ages of 18-50 has shown that this is method with high accuracy. The radioactive activity is direct proportional with the concentration of CA 15-3; The concentration of CA 15-3 in the normal people is 19,12+/-15,54 u/ml in which 90% persons have concentration under 30% u/ml. The concentration of CA 15-3 is most common in 4,71 u/ml.
Tumor Markers, Biological ; Chronic Disease

Subjects: Normal people without the benign or malignant tumor; standard sample of CA72-4 with concentrations: 0,3; 25; 50 100 u/ml. The results have shown that the standard chart has relatively same as theory; the change factor CV had value within allowed limit in the range of low concentration of CA 72-4 was 4,05+/- 3,06U/ml. The medium value was 4,92 u/ml. The normal range is from 0 to 9 u/ml. There is insignificant different between women and men.
Neoplasms ; Immunoradiometric Assay ; Tumor Markers, Biological

The quantification of markers of gastric tumors in healthy people by IRMA has shown that the serum concentrations of CA 72-4 and CA 19-9 in 49 healthy people with ages of 18-49 was 4.05 +/- 3.07 u/ml and 17.12 +/- 11.06, respectively. There was no difference of specific these markers between men and women. These results can be used to compare with markers in patients with gastric tumors.
Attention ; Stomach Diseases ; diagnosis ; Stomach Neoplasms ; neoplasms

Participants were 28 healthy people involved in genders, included smokers and non-smokers with age ranged from 18 to 50 years. Standard curve was established using 6 prepared sample kits of manufacturer with levels of 0, 4, 20, 80, 140 and 200ng/ml. The findings suggested that for technical standard, CEA quantification with IRMA using kits of France-based CIS Bio International was reliable, quality of kits and qualification skill is good. Average level of CEA maker in 28 subjects above is 4.19+/-2.35ng/ml with mean-point of 4.48, ranged from 0.00 to 8.37ng/ml. The most common level is 6.37ng/ml. Upper-marginal level is 2.59ng/ml and under-marginal level is 3.36ng/ml. There was insignificant difference between male and female.
Administrative Personnel ; Carcinoembryonic Antigen ; Immunoradiometric Assay ; neoplasms

The concentration of TSH - receptor autoantibodies (TRAB) in human serum determined. The results of 30 samples of non-Gravis' disease and 30 samples Gravis' disease were as following: Mean of normal: 1.4+/-0.6U/L, mean of abnormal: 182.1+/-193.6U/l. Sensitivity of method: 90%. Specificity of method: 96%. Stability of method: 93%. Accuracy of method: 91%.
Hyperthyroidism ; diagnosis ; Thyrotropin

The concentration of TSH receptor autoantibodies (TRAB) was determined by a Radioreceptor assay kit (RRA) in human serum of normal subjects and Basedow’s patients before and after treatment with antihydroid druf (ATD). The results were as following: Mean TRAB level in Basedow’s patients is higher than that in normal subjects (323.75+/-171.27u/l vs. 1.36+/-0.57u/l). There was not significant difference in the concentration between men and women in both groups. After treatment, the TRAB level was decreased to 10.63+/-11.16u/l.
Graves Disease ; Autoantibodies ; Thyrotropin

The human thyroglobulin (hTG) level was quantified in 31 serum samples taken from healthy people who aged from 18-55 years old. The standard curve, accuracy of technique and the serum hTG level of healthy people was determined. The results showed that the hTG quantified technique using immunoradiometric assay (IRMA) kits of CIS Bio International provided high accuracy. The average serum hTG level of healthy people is 7.35+/-6.99ng/ml; with common rage is 0.00 to 2ng/ml.
Thyroglobulin ; Immunoradiometric Assay

Using the radioimmuno assay to quantify the serum concentrations thyroglobulin and calcitonin in the normal people and patients with the thyroid cancer to evaluate the relation between them and apply this technique for diagnosing the cancer. The comparison found that the serum calcitonin in the patients with the thyroid cancer was lower than this in normal people during the severe or treated phase of the disease. The serum calcitonin concentration was only applied in the phase that the thyroid cells has not been destroyed, phase of relapse or remote metastasis.
Thyroid Neoplasms ; Radioimmunoassay

The serum concentrations of tumor markers of hTG and hCT in 33 healthy people were determined by the immunoradiometry assay (IRMA) has shown that the concentration of hTG and hCT was 7.35 +/- 6.99 mg/ml 5.74 +/-5.92ng/ml, respectively. There was no difference of concentrations of hCT and hTG between men and women.
Thyroid Neoplasms ; Immunoradiometric Assay

The quantification of markers of breast cancer in healthy people (26 people for CA 15-3 and 28 people for CEA) by IRMA has shown that the serum concentration of CA15-3 and CEA was 19.12+/- 15.44 u/ml and 4.19 +/- 2.35 ng/ml, respectively. The medium (4.48), mininum (0.00) and maxinum (8.37) ng/ml. These results can be used to compared with markers in patients with breast cancer. There was no difference of these between men and women.
Breast Neoplasms ; breast