3-thioxo-3-arylamido-4-oxo-1,3thiazan derivatives were obtained by method dithiocarbamat. Condensation of 2-thioxo-3-arylamido-4-oxo-1,3-thiazan derivatives with phenylhydrazin to get 2-thioxo-3-arylamido-4-phenylhydranzon-1,3-thiazan derivatives. The structures of the obtained products were determined by elemental analysis and IR spectroscopy. The study indicated that most of them had low antibacterial and antifungal activities.
Chemical synthesis ; Analogs & derivatives

By condensation of phenylisothiocyanate with amine compounds, thioure derivatives were obtained. The structures of the obtained products were determined by elemental analysis and IR spectroscopy. The study indicated that most of them had antibacterial and anti-fungal activities. Two compounds have good effect on Candida albicans
Chemical synthesis ; Antifungal Agents

Mequinol is a depigmenting (or demelanizer). It was syntheized from hydroquinol and methyliodid or dimethylsulfate, that are available materials. Method is simple and suistable to condition in Vietnam. The structure of the obtained product was characteritsed by chromatography, UV, IR and elemental analysis.
Chemical synthesis ; 4-hydroxyanisole

Four heterocyclic salicylamine derivatives were prepared by condensing of aminoheterocyclic compounds with salicylic acid or its derivatives. The structure of the obtained products were determined by elemental analysis and IR spectroscopy. The sudy indicated that most of them had grater antibacterial and antifungal activities than salicylamide, but all of them did not have effect on Candida albicans.
Chemical synthesis ; Analogs & derivatives ; Salicylic Acid

Using sorbitol - a cheap and easy-to-find material in Vietnam, the authors built a relative optimal and complete protocol to synthesize isosorbide and isosorbide dinitrate (productivity of 64%). Test purity isosorbide dinitrate and solution of 25% isosorbide dinitrate. With purity isosorbite dinitrate: qualitative analysis by IR and test by HPLC method were conducted; isosorbide dinitrate solution was test according to USP 24 and checked by this standard. All products meet USP 24 standard
Isosorbide Dinitrate ; Sorbitol

Dry powder of stem cortex extracted by ethanol 96O. This solution was extracted by ether. The ether extraction had a good antimicrobial activity. 5 compounds TP2, TP3,TP4,TP5 and TP6 were isolated from ether extraction had a good anti microbial activity. Some parameters such as Rf, melting point, UV, IR of TP2, TP3, TP4 and TP5 were identified.
Anti-Bacterial Agents ; Pharmaceutical Preparations ; Plants, Medicinal

CHCl3 extracts of the stem cortex of Annona glabra L killed Artemia salina and inhibited mitosis of root meristem of Allium asca lonicum. Chromatographic fractionation of this extract led to the isolation of Pd1, Pd2, Pd3, Pd4 fractions. The purity of them were controlled by thin layer chromatography. Pd2 was controlled by GC- MS, 1H NMR, 13 C NMR, DEPT. It was not yet found in documents, so that was called anonacin. The study indicated that all of fractions showed cytotoxic activity in experimental tests
Study on the antibacterial effects of leaves of Annona glabra L. Annonaceae

From the cow's bile, which is by product of food manufacture installations in Ho Chi Minh city, was surveyed and built up a progress for isolating cholic acide. From cholic acide by five steps obtained chenodeoxycholic acide. The product come up to the standard of BP 2000
Cholic Acid ; Animal Experimentation ; Chenodeoxycholic Acid

Perform total research 4-fluoroisothiocyanat by dithiocarbamat method, test antibacterial, anti fungus effect by dilute in slate method. Result showed: by response between 4-fluoroanilin and CS2 in ammoniac environment get 4-fluorophenyl dithiocarbamat, which response with lead get 4-fluoro-isothiocyanat. 4-fluorothioure partial towards antifungus, weakly effect in test bacterium
chemical synthesis ; Anti-Bacterial Agents ; Antibiotics, Antifungal ; drugs

The synthesis of some flourosalicylanilid derivatives and the study on their antifungal activities were performed as regard the synthesis: Acid- 4 aminosalcylic was diazoidized, then reacted to NaBF4 solution- Acid 4- flourosalicyanilid was created. Acid 4- fluorosalicylic and salicylic acid were condensed to aniline derivatives for creating 9 derivatives of fluorosalicylic. The synthetized substances were purified, fusion point and thin layer chronatography were determined. In products antibacterial inanifested and antifungal were in experimental concentration. Relatively strong activity of 3'- flourosalicyanilid had exerted on S. aureus; MRSA at the concentration of 9 microgram/ml and 18 microgram/ml; and 3'- flourosalicyanilid, 4'- flourosalicyanilid reacted relatively strongly on Microsporum nanum, Trichophyton mentagrophyle. Microsporum gypseum at the concentration of 2 microgram/ml and microgram/ml
Pharmaceutical Preparations ; Antifungal Agents ; Anti-Bacterial Agents