From October 2004 to March 2005, 13 acute renal failure patients were treated by Continuous Renal Replacement Therapy (CRRT) in Cho Ray hospital. Results: Multiple trauma accounted for 31%, sepsis 31%, multiple system organ failure 15%, APACHE II score were 24.97  6.35. Continuous Intravenous Hemodialysis (CVVHD) had been performed in 39% of patients, CVVH 31%, CVVHDF 15% and SCUF 15%. Patients’ serum concentration of creatinine and BUN decreased step by step and stable. Serum concentrations of creatinine and BUN before and after CRRT were 5.60  2.34 mg% and 49.60  35.19 mg%, respectively. Mean duration of CRRT was 28.0  10.9 hours. 8/13 patients partly recovered their renal functions. Mortality rate was 61.54%. Hemodynamic instability patients (76.92%) were well-tolerated with CRRT. Applying dose of ultrafiltration 35 ml/kg/h for septic patients improved dose and time of increased mean blood pressure. During over 400 hours of CRRT, there were not yet major complications reported.
Renal Replacement Therapy ; Intensive Care

Background: Monitoring antimalarial drug quality should be conducted regularly in locals to enhance the effect of treatment for malaria \r\n', u'Objective: to study and analyze antimalarial drug quality\r\n', u'Subjects and methods: The study was carried out in 2007 for 5 provinces supported by the Global Fund: Ha Giang, Dien Bien, Thanh Hoa, Quang Tri and Gia Lai. Material were malaria drugs: artesunat, chloroquin, quinine, mefloquin, fansidar\u2026etc\r\n', u'Results and conclusion: The strict supervision on the anti-malarial drug quality by the National Malaria Control Program was very good and no substandard antimalarial drugs were detected. Evaluation of antimalarial drug quality and control was made for finding out the counterfeit drugs through sentinel sites in both private and public sectors. A total of 268 samples were collected, of which 13 samples were found substandard drugs (8 samples collected in private and 5 samples in public sectors). No counterfeit drugs were found. \r\n', u'
Antimalarial drug ; quality ; monitoring