Study was performed on the preparation of taurine and some taurate salts in the bile of cow/ox from vissan but chery firm. Average weight of bile adder get 80 g for each. From ethamlanin and die thylcarbonate, 2- oxzolidinon was prepared, after the heating with hydrogene sulphide, taurine was obtained with a productivity of 67,15%. The investigation and extraction of taurine in laboratory scale gave a productivity of 64,5%. From taurine, calcium taurate was prepared at a productivity of 90% and magnesium taurate- 83,5%
Taurine ; Salts ; Pharmaceutical Preparations

Condensation of salicylic acid with anilines made salicylanilid derivatives. From salicylanilids, 3-phenyl-2H-1, 3-benzoxazin-2, 4(3H)-dion derivatives were created by same circle reaction. Thionylation reaction 3-phenyl-2H-1, 3-benzoxazin-2,4(3H)-dion in dioxan solvent had good result. Products of thionylation created thiosalicylanilides after circle opened hydrolysis. Clearness of thiosalicylanilides was determined by thin layer chromatography and their structure was determined by UV, IR.H1 MNR. Antibacterial effect of synthetic products, especially Streptococcus feacalis E.coli was higher than control substance as salicylanilid. Antifungal effect of Bromo and clorothiosalicylanilide derivatives was stronger than other derivatives
Anti-Bacterial Agents ; Plants, medicinal

3-thioxo-3-arylamido-4-oxo-1,3thiazan derivatives were obtained by method dithiocarbamat. Condensation of 2-thioxo-3-arylamido-4-oxo-1,3-thiazan derivatives with phenylhydrazin to get 2-thioxo-3-arylamido-4-phenylhydranzon-1,3-thiazan derivatives. The structures of the obtained products were determined by elemental analysis and IR spectroscopy. The study indicated that most of them had low antibacterial and antifungal activities.
Chemical synthesis ; Analogs & derivatives

By condensation of phenylisothiocyanate with amine compounds, thioure derivatives were obtained. The structures of the obtained products were determined by elemental analysis and IR spectroscopy. The study indicated that most of them had antibacterial and anti-fungal activities. Two compounds have good effect on Candida albicans
Chemical synthesis ; Antifungal Agents

Mequinol is a depigmenting (or demelanizer). It was syntheized from hydroquinol and methyliodid or dimethylsulfate, that are available materials. Method is simple and suistable to condition in Vietnam. The structure of the obtained product was characteritsed by chromatography, UV, IR and elemental analysis.
Chemical synthesis ; 4-hydroxyanisole

Four heterocyclic salicylamine derivatives were prepared by condensing of aminoheterocyclic compounds with salicylic acid or its derivatives. The structure of the obtained products were determined by elemental analysis and IR spectroscopy. The sudy indicated that most of them had grater antibacterial and antifungal activities than salicylamide, but all of them did not have effect on Candida albicans.
Chemical synthesis ; Analogs & derivatives ; Salicylic Acid

Using sorbitol - a cheap and easy-to-find material in Vietnam, the authors built a relative optimal and complete protocol to synthesize isosorbide and isosorbide dinitrate (productivity of 64%). Test purity isosorbide dinitrate and solution of 25% isosorbide dinitrate. With purity isosorbite dinitrate: qualitative analysis by IR and test by HPLC method were conducted; isosorbide dinitrate solution was test according to USP 24 and checked by this standard. All products meet USP 24 standard
Isosorbide Dinitrate ; Sorbitol

Dry powder of stem cortex extracted by ethanol 96O. This solution was extracted by ether. The ether extraction had a good antimicrobial activity. 5 compounds TP2, TP3,TP4,TP5 and TP6 were isolated from ether extraction had a good anti microbial activity. Some parameters such as Rf, melting point, UV, IR of TP2, TP3, TP4 and TP5 were identified.
Anti-Bacterial Agents ; Pharmaceutical Preparations ; Plants, Medicinal

CHCl3 extracts of the stem cortex of Annona glabra L killed Artemia salina and inhibited mitosis of root meristem of Allium asca lonicum. Chromatographic fractionation of this extract led to the isolation of Pd1, Pd2, Pd3, Pd4 fractions. The purity of them were controlled by thin layer chromatography. Pd2 was controlled by GC- MS, 1H NMR, 13 C NMR, DEPT. It was not yet found in documents, so that was called anonacin. The study indicated that all of fractions showed cytotoxic activity in experimental tests
Study on the antibacterial effects of leaves of Annona glabra L. Annonaceae

From the cow's bile, which is by product of food manufacture installations in Ho Chi Minh city, was surveyed and built up a progress for isolating cholic acide. From cholic acide by five steps obtained chenodeoxycholic acide. The product come up to the standard of BP 2000
Cholic Acid ; Animal Experimentation ; Chenodeoxycholic Acid