1.Influence of rice and added sugar intakes on fasting plasma glucose and triacylglycerol levels amongst a population sample of Malaysian adults
Zhi Yee Lee ; Joshua Chuan Yung Foo ; Mei Qian Lim ; Zheng Xian Koh ; Wendy Hui Yi Wong ; Tony Kock Wai Ng
International e-Journal of Science, Medicine and Education 2015;9(1):26-31
Introduction: A recently published meta-analysis
showed that each additional serving of rice increased
risk of type 2 diabetes mellitus (DM) by an alarming
11%. We investigated whether this phenomenon is seen
in the Malaysian population by studying the effect of rice
intake and added sugar consumption on fasting plasma
glucose (FPG) and fasting triacylglycerol (TAG).
Methods: Ninety subjects (60 females, 30 males, aged
30-70 years), adequate to detect a weak-to-moderate
Pearson correlation of r=0.26 at a=0.05 and power=
0.80, were recruited by convenience sampling from six
communities in the Klang Valley, Malaysia. Fasting blood
samples were collected by finger-prick and analysed for
FPG (AccuCek, Roche) and TAG (Accutrend, Roche).
Macronutrient intakes, including rice, were obtained
by a single interview using a previously-evaluated food
frequency questionnaire (FFQ) and quantitated as grams
by the DietPLUS V2 programme. Added sugar intakes
by subjects were estimated using an Added Sugar Intake
excel programme.
Results: Rice contributed to 85% of dietary
carbohydrates, accounting for 41.8 % kcal of the average
1750- kcal diet. Rice intakes or added sugar consumption
did not have a significant correlation (p>0.05) with
FPG nor fasting TAG. Added sugar consumption, which
averaged 44g/person/day (5% kcal) was markedly lower
than the 137g/person/day reported elsewhere for the
Malaysian population.
Conclusion: High consumption of rice as a risk factor of
type 2 DM was not indicated in the present study. Since
white rice consumption varied 10-fold in the present
subjects, the reduction in daily intake of this staple food
represents a feasible option for cutting back on calorie
intake for overweight or obese individuals.
Triglycerides
2.Diagnostic value of cholesterol and triglyceride in pleural andascitic fluid.
Eun Sook CHUNG ; Sang Jin EUN ; Kyung Eun SONG ; Jang Soo SUH ; Won Kil LEE ; Jay Sik KIM
Korean Journal of Clinical Pathology 1992;12(3):291-298
No abstract available.
Cholesterol*
;
Triglycerides*
3.A Comparative Study on the Interlaboratory Triglyceride Determination.
Myung Jin KIM ; Tae Young KIM ; Won Sang YOO
Korean Circulation Journal 1979;9(1):23-25
Quality control survey was done on the plasma triglyceride determination of six laboratories and following results were obtained. 1) Coefficients of variation were less than 5% in 3 laboratories and over 10% in one laboratory. 2) High interlaboratory variation was inferred from the mean values ranging from 104.0~136. 4mg% (sample A) with enzyme method and 44.7~65.3 (Sample B) with acetylaceton method. 3) Establishment of normal plasma triglyceride level in Koreans and supervised quality control by the authority seemed to be urgent.
Plasma
;
Quality Control
;
Triglycerides*
4.Study on the effect of antihypertensive drug NHL on cholesterol & triglycerid of plasma in patient with hypertention & hyperlipaemia
Journal of Vietnamese Medicine 2005;310(5):17-21
This research was carried out on 39 patients between 40 and 70 of ages, who had hypertension of degree I, II, with hyperlipaemia but without complications. Total cholesterol, serum triglyceride were quantified according to enzyme method on automatic biochemical analysis machine. The results showed that: concentration of total cholesterol in these 39 patients who treated with antihypertensive herbal remedy Nguu tat, Hoe hoa, Linh chi 3g/day during 30 days decreased clearly (8.6%), serum triglyceride concentration reduced 0.32mmpl/l (~9.94%)
Hypertension
;
Cholesterol
;
Triglycerides
;
Plasma
5.Effect of Pantethine in the Treatment of Hyperlipidemia.
Kyung Pyo HONG ; Chung Hoo KANG ; Myoung Mook LEE ; Young Bae PARK ; Jungdon SEO ; Young Woo LEE
Korean Circulation Journal 1982;12(2):225-229
After pantethine in doses of 540 mg per day was administered for 8 weeks in 20 patients with hyperlipidemia, the serum levels of total cholesterol, triglyceride and HDL-cholesterol were compared with the pretreatment level. The serum level of total cholesterol decreased to 240+/-52 mg%[mean+/-standard deviation] after 4 weeks and 223+/-41 mg% after 8 weeks from the pretreatment level of 293+/-38 mg%(p<0.01). The serum triglyceride level also decreased to 254+/-109 mg% after 4 weeks and 239+/-114 mg% after 8 weeks from the pretreatment level of 375+/-126 mg%(p<0.01). But, there was no significant change in the serum levels of HDL-cholesterol before and after treatment (56+/-27 mg% beforAfter pantethine in doses of 540 mg per day was administered for 8 weeks in 20 patients with hyperlipidemia, the serum levels of total cholesterol, triglyceride and HDL-cholesterol were compared with the pretreatment level. The serum level of total cholesterol decreased to 240+/-52 mg%[mean+/-standard deviation] after 4 weeks and 223+/-41 mg% after 8 weeks from the pretreatment level of 293+/-38 mg%(p<0.01). The serum triglyceride level also decreased to 254+/-109 mg% after 4 weeks and 239+/-114 mg% after 8 weeks from the pretreatment level of 375+/-126 mg%(p<0.01). But, there was no significant change in the serum levels of HDL-cholesterol before and after treatment (56+/-27 mg% before treatment, 56+/-18 mg% after 4 weeks and 59+/-22 mg% after 8 weeks). Pantethine was well tolerated in most patients.
Cholesterol
;
Humans
;
Hyperlipidemias*
;
Triglycerides
6.Trend of Serum Lipid Levels in Normal Koreans.
Sung Wook HAN ; Dong Ho SHIN ; Sang Eun JOO ; Bang Hun LEE ; Chung Kyun LEE
Korean Circulation Journal 1983;13(1):107-112
The authors underwent the serum lipid study, involving the lipoprotein fraction, and the HDL-cholesterol mean values in normal Korean adults visited to Hanyang University Hospital, and also compared with the previously reported serum lipid studies. The results are as follows; 1) The mean values of triglyceride, total cholesterol, and phospholipid were 103.3+/-17.1mg%, 188.9+/-18.2mg%, and 196.7+/-19.8mg%, respectively. 2) Compared with the past 7 years triglyceride showed increasing tendency with significance, and cholesterol and phospholipid showed slightly increasing tendency. 3) In the serum lipoprotein fraction, the mean values of alpha-lipoprotein, pre-beta-lipoprotein, and beta-lipoprotein were 37.2+/-5.9%, 16.0+/-4.2%, and 48.6+/-5.2%, respectively. 4) Compared with the past 10 years, the alpha-, and pre-beta-lipoprotein showed increasing tendency, meanwhile, beta-lipoprotein revealed decreasing tendency. 5) The mean value of HDL-cholesterol was 52.3+/-14.6mg%, and the ratio of HDL-cholesterol to total cholesterol(HDL-cholesterol/total cholesterol) was 28.2+/-7.9. 6) Compared with the past 2 years, HDL-cholesterol level showed slightly increasing tendency.
Adult
;
Cholesterol
;
Humans
;
Lipoproteins
;
Triglycerides
7.The role of triglyceride-glucose index in the prediction of the development of hypertension – findings from a community cohort in Singapore
Jonathon Khoo ; Serena Low ; Bastari Irwan ; Justin Tang ; Chee Fang Sum ; Tavintharan Subramaniam ; Su Chi Lim
Journal of the ASEAN Federation of Endocrine Societies 2023;38(1):62-67
Objectives:
Triglyceride-glucose index (TyGI) is an emerging surrogate marker of insulin resistance. We aim to explore the role of triglyceride-glucose index in the prediction of the development of hypertension.
Methodology:
nducted a retrospective cohort study that included 3,183 study participants identified from a community health screening programme who had no baseline hypertension and were then followed up after an average of 1.7 years. Cox proportional-hazard model was used to assess the association between risk of incident hypertension and TyGI in quartiles, while adjusting for demographics and clinical characteristics.
Results:
Hypertension occurred in 363 study participants (11.4%). Those who developed hypertension had higher TyGI [8.6 (IQR 8.2-9.0)] than those who did not [8.2 (IQR 8.0-8.7)] (p<0.001). Significant association between TyGI and hypertension was observed in both the unadjusted and proportional hazard model [Quartile (Q)2, p=0.010; Q3, p<0.001 and Q4, p<0.001] and the model that adjusted for demographics (Q2, p=0.016; Q3, p=0.003; Q4, p<0.001). In the model adjusted for clinical covariates, the hazard of developing hypertension remained higher in TyGI Q4 compared to TyGI Q1(Hazard Ratio=2.57; 95% Confidence Interval: 1.71, 3.87). Increasing triglyceride-glucose index accounted for 16.4% of the association between increasing BMI and incident hypertension, after adjusting for age, gender, ethnicity and baseline HDL cholesterol (p<0.001).
Conclusion
Triglyceride-glucose index was an independent predictor of the development of hypertension. It may potentially be used as an inexpensive indicator to predict the development of hypertension and risk-stratify individuals to aid management in clinical practice.
Diabetes Mellitus
;
Triglycerides
;
Hypertension
;
Screening
8.A study of Serum Triglyceride and Cholesterol in Korean Mothers and New born Infants.
Journal of the Korean Pediatric Society 1981;24(11):1028-1038
No abstract available.
Cholesterol*
;
Humans
;
Hypertriglyceridemia
;
Infant*
;
Mothers*
;
Triglycerides*
9.Clinical Efficacy of Lovastatin in Patients with Hypercholesterolemia.
June Soo KIM ; In Ho CHAI ; Seung Woo PARK ; Suk Keun HONG ; Hyo Soo KIM ; Cheol Ho KIM ; Dae Won SOHN ; Byung Hee OH ; Myoung Mook LEE ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1992;22(1):121-129
BACKGROUND: This study was designed to evaluate the clinical efficasy of lovastatin, HMG-CoA reductase inhibitor, in patients with hypercholesterolemia. METHODS AND RESULTS: Lovastatin 20 to 80 mg were administered once daily for 12 weeks in twenty five patients(11 male, 14 famale ; nine patients with familial hypercholesterolemia) with hypercholesterolemia(>240mg/dl). Compared with pretreatment levels, lovastatin significantly decreased levels of total cholesterol(309+/-46mg/dl versus 201+/-37mg/dl) by 35%, LDL-cholesterol(230+/-48mg/dl versus 125+/-40mg/dl) by 46% and triglyceride(170+/-76 versus 142+/-66mg/dl) by 11% (p<0.05) with significantly decreased levels of total-cholesterol/HDL-cholesterol ratio(7.4+/-2.1 versue 4.6+/-1.5) and LDL-cholesterol/HDL-cholesterol ratio(5.6+/-1.9 versue 2.9+/-1.4) (p<0.005 except triglyceride, respectively). The level of Apo B(183+/-32mg/dl versus 114+/-26mg/dl) was decreased significantly by 37%(p<0.005) with significantly decreased level of Apo A-1(115+/-22 to 122+/-26mg/dl) was increased significantly by 6%(p<0.05). No serious side effects were found. CONCLUSIONS: Results from the present study show that lovastatin is an effective and well-tolerated cholesterol-lowering agent.
Humans
;
Hypercholesterolemia*
;
Lovastatin*
;
Male
;
Oxidoreductases
;
Triglycerides
10.Congenital Chylothorax.
Jong Wie CHOI ; Do Kwang YUN ; Pyung Kil KIM ; Kyung Soon SONG
Journal of the Korean Pediatric Society 1982;25(7):748-752
Chyle is the digestive product absorbed from intestinal lymphatics which the component have high concentration of triglyceride and protein. The various pathological circumstances which give rise to intrathoracic effusion of chyle are well documented and so the etiology is clearly defined in most instances. However, the occurrence of chylothorax in early infancy, in the absence of other demonstrable diseases and without apparent birth trauma, suggests the existence of congenital malformation of the thoracic ducts. We lately experienced a 20 day old new born who was proved to have congenital chylothorax by clinical history and laboratory findings. So we report the clinical findings and laboratory findings with the review of the literatures on congenital chylothorax.
Chyle
;
Chylothorax*
;
Parturition
;
Thoracic Duct
;
Triglycerides