Introduction: In the present scenario there are many qualified nursing human resources with flawless emotional personality but with errors in job accomplishment, lack of accuracy and delays in working completion, low working motivation, as well as careless and insincere working. The qualified nursing human resources must consist of nurses with a passion for work and with creativity. They must be proactive, with great deal of warmth and smiles. Based on the required nursing competences, it is found that the on-duty nurses should acquire several vital proficiencies such as leadership qualities, proper working procedures, interpersonal/soft skills, and environmental control. Soft skills may be developed and improved through various ways like trainings, modification of the environment, and with appropriate nursing education. Methods: The research population consists of 18 master's degree nursing students of a hospital divided into a control and experimental group (total sampling), and 47 on-duty nurses who are collected through a random sampling technique. Results: The results of the present study show that the implementation of transformational leadership model is effective to improve nurses' soft skills in terms of self-assurance, communication, compliance, teamwork, precision, discipline and problem solving. There were also noteworthy changes after the model implementations based on 1st month and 2nd month and then on those at 1st month and 3rd month. Conclusion: The Soft Skills-Based Transformational leadership model is highly applicable in nursing care units of all hospitals to meet the challenges of the world in improving human resources by means of improvement of performance. With respect to soft skills and intrapersonal skills as well as the frequently neglected nurses' daily activities and portfolio worksheets are highly effective in dealing with the model applications.