1.Some opinions of the natural transform of the diseases in the myelo-proliferative syndrome (MPS)
Journal of Practical Medicine 2002;435(11):28-31
MPS comprised 4 disease's forms, such as: Chronic myelogenous leukemia (CLM), polycythemia vera (PV), essential thrombocytothemia (ET) and idiopathic myelofibrosis (IMF). From 1985 to May-2001 at Friendship hospital, authors have followed up a group of 86 patients with MPS and some remarks had been drawn out: Some disease's forms of MPS can transform each other, such as: +PV transformed in to CML: 10.00%; +PV transformed in to ET: 16.67%; +IMF transformed in to CML: 66.67%; +ET transformed in to CLM: 8.0%. Some case in MPS, although have not yet truly transformed, but have some changes, as such: +ET with concomitantly increasing erythrocytes: 4.0%; +IMF with concomitantly increasing platelets: 33.33%; +CML with concomitantly increasing platelets: 21.43%; Authors have also mentioned many interesting issues about the way of transformation, the last diagnosis for those disease's forms and the prognosis of these transformations
Leukemia, Myeloid
;
Polycythemia Vera
;
Syndrome
2.Clinical features of patients with myeloproliferative syndrome (MPS)
Journal of Practical Medicine 2002;435(11):21-2
This study included 55 patients who admitted to Huu Nghi Hospital from 1985 to 1998. It is found that spleen enlargement is common in myeloproliferative conditions, with the incidence is 100% of patients who have chronic granulocytic leukemia and those have idiopathic myelosclerosis. These patients have grade II or more of spleen enlargement. This symptom is less common in patients who have polycythemia vera or essential trombocythemia, and these patients are likely to have grade I of spleen enlargement. Anemia is more likely to be found in patients with chronic granulocytic leukemia, especially in those with idiopathic myelosclerosis, but this symptom is infrequent in patients with essential trombocythemia. Patients with polycythemia vera in typical have excessive blood. Infection and hemorrhage occurred predominantly in patients with chronic granulocytic leukemia and in some cases of essential trombocythemia. Symptoms of high blood pressure, tip finger bruise and limb weakness have been found mainly in patients with polycythemia vera. In some cases with polycythemia vera, both red cell and white cell counts are increased. While patients with chronic granulocytic leukemia, polycythemia vera and idiopathic myelosclerosis expresses obvious clinical symptoms, the symptoms in patients who have essential trombocythemia are unmarked.
Myeloproliferative Disorders
;
Hemorrhage
;
diagnosis
;
syndrome
3.The cytological features of patients with myeloproliferative syndrome
Journal of Practical Medicine 2002;435(11):18-20
Objectives: Finding the markers/symptoms of cytology for each disease and all diseases belonged the myeloproliferative syndrome (MPS). Subjects: 55 patients in the H÷u NghÞ Hospital during 1985-1998. Results: The increased leukocytes and immature cells found in the peripheral blood of patients with MPS. However, the level and rate of these were different: 1st increased level (chronic granulocytic leukemia, 2nd increased level (essential myelofibrosis), 3th increased level(primary multi erythro was always accompanied with erythrocythmia where as the chronic granulocytic leukemia and essential myelofibrosis were accompanied with anemia. The primary thrombocythenia remains the normal erythrocyte. The thrombocythenia is not a obviously marker in the primary thrombocyte but also in the chronic granulocytic leukemia and the primary multierythrocyte. The thrombocyte found in the peripheral blood of patients with myeloproliferative syndrome. The number of marrow cells were reduced in the essential myelofibrocythemia remained at normal level. The significant increased number of marrow cells found in the most of patients with the chronic granulocytic leukemia. The obvious increased rate of germ cell of granulocyte and thrombocyte in the marrow cell picture.
Myeloproliferative Disorders
;
cytology
;
diagnosis
4.Preliminary assessment of adverse side effects of some procedure of chemotherapy against malignancy of hemopoietic organs
Journal of Practical Medicine 2003;463(10):44-46
Most of chemical drafts that treatment malignant disease at blood- forming organs have side effects as: reduce aleukemia, glomerule, blood pigment, increase ure, creatinin or nauseate, voltmit, lose hair. However, rate and level are different in each of drafts. The other drafts, that made side effects are Doxorubicin + Ara.C (P3), MOPP (P2), CHOP (P1) and VAD (P4). Ara.C + Depersolon (P7), Hydrea + Ara.C (P6) drafts and especially is only use single Hydrea dafts that has little side-effect
Hematologic Neoplasms
;
drug therapy
;
Pharmaceutical Preparations
5.Investigation of HBeAg marker and anti HBe in subjects with positive HBsAg
Journal of Practical Medicine 2003;442(2):96-98
In 242 subjects (68 female, 174 male), ELISA technique was performed with the set of ORGANON TEKNIKA UNIFORM II. Result showed a HBeAg positive rate of 37.42% on HBsAg positive subjects.
The rate of HBsAg positive subjects having anti HBsAg is 56.61%. In 38.9% of B viral hepatitis patients, recession of the condition was noted on laboratory examinations
Hepatitis B Surface Antigens
;
Hepatitis B e Antigens
;
Diseases
;
Liver Diseases
6.Study on some laboratory test indicators of hemostasis and blood coagulation in normal persons
Journal of Practical Medicine 2003;445(3):20-23
120 normal subjects without bleeding history aged 20-77 were studied. Bleeding time 169 seconds, there is no significant statistic difference in genders and age groups. Plasma fibrinogen level was 2.56 g/l, no significant difference in 2 genders. In the under 45 years old group, fibrinogen level was lower than in above 45 yeas old group with statistical significant. No case of non-contracted blood clot occured, 2.5% of blood clot was contrated non completely, 97.5% completely. Alcohol test was negative in all cases. No case of fibrinolyse time < 90 minutes occured.
Hemostasis
;
Blood Coagulation
;
Laboratories
7.Study on management of in patients with hematological diseases
Journal of Practical Medicine 2000;392(12):66-69
Among 512 patients are under management of friendship hospital during 1987 –2001, 431 patients with hematological diseases in which there were 405 inpatients and 26 outpatients. The results showed that most of patients with hematological and hematopoietic diseases can be management in family such as primary marrow fibrosis, malignant lymphoma, hemolytic anemia in order to reduce the rounds of admission to hospital and complication and maintain normal life. The management in the families involved the consultation, tests and prescription for use at home.
Hematologic Diseases
;
Leukemia
;
Anemia, Aplastic
;
Anemia, Hypochromic
8.Values of fibrinogen degradation products (FDPs) and D-dimmer in healthy people
Journal of Practical Medicine 2002;435(11):42-43
The study involved 32 healthy blood donors (16 men and 6 women). Plasma D-dimer and FDPs levels were determined by semi-quantitative method, using chemical procedure of the Stago Inc., France. The results showed that plasma FDPs level in healthy people was lower than 40 g/ml (93.75% of the participants had lees than 20 g/ml). Plasma D-dimer level was 1-4 g/ml, with 75% of the participants had D-dimer values ranged from 1 to 2 g/ml.
Fibrin Fibrinogen Degradation Products
;
Pharmaceutical Preparations
9.Primarily results of the application of test hemoglobin A1c (HBA1C) in the clinical diagnosis and treatment of the diabetes mellitus
Journal of Practical Medicine 2000;392(12):42-44
A study on the 55 patients (27 patients with diabetes mellitus and 28 patients with the suspecting of diabetes mellitus) in the hematology and blood transfusion department of friendship hospital was carried out. The patients received the quantitative analysis of HbA1C by Diastat. The relation of HbA1C with glycemia was evaluated. The results were reported that the rate of patients with the high concentration of HbA1C is valuable. There was a direct correlation between HbA1C and glycemia in the most of patients.
Diabetes Mellitus
;
diagnosis
;
therapeutics
10.The serum viscosity in Vietnam people
Pharmaceutical Journal 2002;318(10):56-58
The evaluation of serum viscosity contributes to the diagnosis of some hematopathology, cardiopathology. A study on 303 healthy persons with ages of 18-81 in Hanoi was carried out to determine the Vietnamese serum viscosity. The results have shown that the serum viscosity found in the normal people was 9.180.47 (1.52-2.45). There is no significant different of the serum viscosity between men and women. The serum viscosity is gradually increased as increased age.
Viscosity
;
serum