Translational Medical Research ; standards

Toxicology ; Translational Medical Research

No abstract available.
Pathology* ; Translational Medical Research*

No abstract available.
Ion Transport* ; Translational Medical Research*

Humans ; Singapore ; Translational Medical Research

Epidemiologic Methods ; Translational Medical Research

Epidemiologic Studies ; Translational Medical Research

Over the last decade, as tremendous innovations have been achieved in scientific technology, translational medicine has come into the focus of academic medicine, and significant intellectual and financial efforts have been made to initiate a multitude of bench-to-bedside projects. The concept of translational medicine is described as the transfer of new understandings of disease mechanisms gained in the laboratory into the development of new methods for diagnosis, therapy, and prevention and their first testing in humans, meanwhile, translational medicine also is described as a patient-oriented population research and the translation of results from clinical studies into everyday clinical practice and health decision making. Translational medicine is a hot spot in recent academic field, and it is crucial for improving the living standard of population and renewing the research idea and technology. It has, however, significant obstacles during the approach of translational medicine. We here review the background, concept, current situation of translational dental medicine, key components and obstacles of translational medicine.
Dentistry ; Humans ; Research ; Translational Medical Research

Translational medicine is an emerging arena in the 21st century, and it bridges research results of basic sciences to clinical applications. The importance of translational research attracted considerable concern of scientists worldwide, including clinicians and researchers in the field of burn surgery in China. This review highlights some key points on translational medicine practised in the basic and clinical research of burn surgery, and they are summarized here as: the motive of the research project should be focused on how to solve problems of patients; much attention should be drawn to the difference between the cell biology and biochemical reaction in vitro and that in vivo; an animal model which simulates human pathology as much as possible should be reproduced; collaboration and sharing of resources among different disciplines should be strengthened; national and standardized criteria should be established for evaluation of the experimental result and guiding for clinical application. The aforementioned suggestions would be helpful for the application of new medicine and therapeutic approach in treating severe burn.
Burns ; surgery ; Humans ; Translational Medical Research

This article endeavours to reiterate the advances in six vital aspects of burn injury, i.e. shock/ischemia-hypoxia, infection/sepsis, inhalation injury, regenerative medicine/tissue engineering and wound repair, hypermetabolism after burn, and integration of early treatment and rehabilitation in the last three decades. They originated from the papers dealing with ten main episodes in the care of burn trauma as a token to commemorate the 10th anniversary of Chinese Journal of Burns, as well as the 30th anniversary of the inauguration of Chinese Burn Association.
Burns ; therapy ; China ; Humans ; Translational Medical Research