Designing technological process to assess bioequivalence of oral antibiotic products. Method: Choosing volunteers, setting experiment, taking specimens, following volunteers' health, quantifying cephalexine in specimens, and analysing experiment data. The method assessed by drug's hardness, accuracy, limitation of quantification, stability
Cephalexine ; Biological Products ; Hospital Volunteers

A study on 70 adult patients with the cerebrovascular accident in Friendship Hospital during 1999-2001 has shown that most of patients were men with ages of 60 and over and history of hypertension. The general mortality rate was 24%. 95.7% of patients had blood clot, mainly in the central grey matter region, with size of 3 cm. Most of the secondary cerebral ventricular haemorrhages related with the conscious disorder. The severe conscious disorder lead to the high mortality rate. The cerebral haemorrhage occurred in many regions such as cerebellum, brain stem. The cerebral haemorrhage combining with encephalocele had a bad prognosis.
Cerebrovascular Accident ; prognosis ; diagnosis

A prospective randomized study was performed to study the hemostatic effect of injection therapy with adrenaline 1/10,000 in the treatment of ulcerated peptic bleeding (PUB). 30 patients with PUB were included. The treatment was performed until bleeding stopped, in case of relapse or in risk of relapse, the injection was repeated. Successful rate was 100%. Stable condition (stop bleeding) after the first injection was observed in 16 patients (53.3%). The number needed the second injection were 14 patients (36.6%).There were 3 patients needed the third injection. Dose of adrenalin for each bleeding site: 8.9 +/- 1.2 ml, number of injections: 4.2+/- 1.0 injection (maneuver) time: 21+/- 6.2 minutes. Adrenalin were effective in stop bleeding, but had to reapeat. Using adrenalin is safety and low cost.
Therapeutics ; Peptic Ulcer ; Peptic Ulcer Hemorrhage

From March 2001 to August 2001, at the Military Hospital N0 108, 185 cases of gastrointestinal hemorrbiage due to gastroduodenal ulcer were managed, among them 55 bleeding cases by HSE injection. The incidence of this hemorrhage was higher in male patients than in femal and a majority of patients was in productive age. HSE injections gave successful results on 100%. The rate of success in the 1st injection attained in 47 cases (81.2%), in 8 cases (18.2%) the bleeding recured or had got the risk of recurrent bleeding and an injection again to cease the hemorrhage was needed. There was 1 patient needed the third injection. The mean dose of efficacy for 1 bleeding ulcer attained 8.82.6ml with 4.01.2 injections. The time of injection was 17.35.1 minute. HSE were effective in stop bleeding, using HSE is simplicity, safety and low cost.
Epinephrine ; Therapeutics ; Peptic Ulcer ; Peptic Ulcer Hemorrhage ; Peptic Ulcer ; Endoscopy

Background: Deltoid contracture can be a congenital or acquired condition. There were not any reports on deltoid contracture in English literature until 1960. In 2005 there were 170 children presented at the Viet Nam Pediatric Institute with deltoid contracture. These children came from different provinces, nationwide. The numbers of children who have this condition is increasing, but there were few studies on this problem in Viet Nam. Objectives: To identify the prevalence of deltoid contracture in Viet Nam in 2006-2007. Subjects and method: A cross-sectional study was done in 8 provinces representing for 3 geographic regions of Viet Nam., included Ha Noi, Ha Tay, Thanh Hoa and Lang son in Northern, Ha Tinh and Da Nang in Central and Tien Giang and Can Tho in the Southern region. 29,696 people aged from 1 to 60 years old at the baseline were involved in the study. The subjects were examined to identify the deltoid contracture based on defined criteria. Results: The prevalence of disease was 0.65% (0.83% in men and 0.51% in women). The rate was highest in the group of 6-10 years of age (1.81%). The prevalence was 0.82% in rural and 0.31% in urban area. Cases were found in all but 4 provinces (Da Nang, Tien Giang, Can Tho and Ha Noi) Conclusion: The prevalence of Deltoid contracture in Viet Nam was 0.65% in 2006-2007. It was more likely to occur in men than in women, in age group of 6 \u2013 10 than in other groups and in rural than in urban area.
Deltoid contracture

Background: Deltoid contracture can be congenital or acquired. A cross-sectional study has been done in 8 provinces representing three regions in Vietnam. These are Ha Noi, HaTay, Thanh Hoa and Lang Son in the North, Ha Tinh and Da Nang provinces in the central, Tien Giang and Can Tho provinces in the South of Vietnam. Objective: To identify the risk factors of Deltoid contracture in Vietnam from 2006 - 2007. Subject and Method: 29696 people aged from 1 to 60 years old at the time of the survey were examined to diagnose the Deltoid contracture as well as being interviewed by structured questionnaire. Results: There was significant association between contracture of Deltoid muscle and some factors. These are antibiotics injection into the Delta muscle at 0 - 5 years old: OR = 2.93 (1.435,8); Antibiotics type (streptomycin) was injected at 0-5 years old: OR = 45.2 (13.1 - 167); having cicatrix: OR = 73.4 (46.1 - 116.9). There was no significant association between Deltoid fibrosis and vaccination (position and administration). Logistic regression was done to find that antibiotics injection into Delta muscle at 6 - 10 years old and antibiotics type (streptomycin) were significantly associated with Deltoid contracture. Conclusion: Risk factors of Deltoid contracture in this study were antibiotic injection at aged 0 - 5 years old, antibiotic type (Streptomycin) and having cicatrix. There was no significant association between Deltoid fibrosis and vaccination (position and administration).
Deltoid contracture ; Risk factors ; Vietnam

Background: Dengue fever remains a major public health problem in Vietnam. It was transmitted through two main Aedes species, namely Aedes aegypti and Aedes albopictus in which Aedes aegypti played the predominant role in transmitting the dengue viruses (accounted for 94% of the Aedes genus).Different groups of insecticides have been widely used in the community. As a consequence, it increased the resistance level of Aedes vectors to the insecticides. Therefore, a new synthesized insecticide was required for future control and prevention of dengue epidemics. \r\n', u'Objectives: To evaluate the efficacy of Cynoff 25 ULV in suppressing Aedes species in Vietnam. \r\n', u'Subjects and methods: The study was conducted in the entomology laboratory and in the fields of Ha Tay province. ULV spraying was implemented in Hiengiang commune, Thuongtin district, in comparison with a control area, Van Mo commune in Ha Dong town.\r\n', u'Results and conclusions: : Cynoff 25 ULV had a high efficacy that kills over 90% of 2 dengue vector species, namely Aedes aegypti and Aedes albopicctus after 24 hours exposure at the distance of 30 meters from the brass nozzle of a STIHL SR 400 sprayer. In the field trials, Cynoff 25 ULV also had high efficacy in killing Aedes species, e.g. 100% of Aedes species were killed after spraying and the effects lasted for 3 months for Aedes aegypti and one month for Aedes albopictus species. The insecticide had no side-effects or any other adverse effects to humans, livestock and the environment in the intervention areas. \r\n', u'
cynoff 25 ULV ; aedes species ; dengue vectors

Background: Two species, Aedes aegypti and Aedes albopictus are the main intermediate vectors of transmission of the dengue viruses in Vietnam. Insecticide applications by different methods that may help interrupt the spread of dengue outbreaks. Many different groups of insecticides have been used for dengue vector control. Some recent studies revealed that Aedes vectors obscuring their resistance to insecticides at different levels. Therefore, a new insecticide formula is required for effective dengue vectors control. Objective: To evaluate the efficacy of Bistar 80SC by residual application in suppression of Aedes species in a northern province of Vietnam. Subject and methods: Bistar 80 SC with a component of Bifenthrin 80g/L was evaluated by residual application in suppression of 2 Aedes species in vitro and in an intervention commune of Hien Giang, Thuong Tin district and a control commune of Van Mo, Ha Dong town, Ha Tay province from March, 2004 to June, 2004. Results: WHO Bifenthrin paper test kit was effective at the concentration of 37.5mg/m2 and over with Aedes aegypti vectors ranged from 80% to 100% mortality in the North, In other words, Aedes vector remains susceptible to Bifenthrin in the region. The mortality on wood surface after 60 minutes of exposure to Bistar 80SC at concentrations of 25mg/m2 by using residual application was higher than those on brick walls. Up to 100% Aedes aegypti was killed after 60 minutes in exposure and remains in effect until the end of the third months and one month with Aedes albopictus. No side effects, to the sprayer and humans, livestock and environment caused by Bistar 80SC were reported in the intervention area. Conclusion: Bistar 80SC is suggested as a nominated alternative to effectively control the dengue outbreak by residual application.
Bistar 80SC ; dengue vectors

OBJECTIVES: The prevalence of diabetes mellitus is rapidly increasing in Vietnam, particularly among adults aged over 45 years. This study estimated trends in diabetes and prediabetes prevalence and determined risk factors in Vietnamese adults (over 45 years). METHODS: A cross-sectional study was conducted based on data from an annual diabetes screening program among people aged 45-69 years in an urban city in central Vietnam (Da Nang). Joinpoint regression analyses were performed to calculate the annual percentage change and ptrend-values. Multinomial logistic regression analysis was used to determine risk factors. RESULTS: In total, 3,765 men and 9,149 women were included in this analysis. The age-adjusted prevalence of diabetes and prediabetes in 2017 was 11.4% and 52.9%, respectively. The prevalence of diabetes was higher in men (15.1%) than in women (10.3%), but that of prediabetes was similar in both genders (53.4% vs. 52.8%). The prevalence of prediabetes significantly increased during the study period, whereas no upward or downward trend for diabetes was observed. The prevalence of obesity, abdominal obesity, hypertension, and dyslipidemia showed no obvious trend. Obesity, a high waist-to-hip ratio, hypertension, more severe abdominal obesity, and dyslipidemia were significantly associated with a higher risk of diabetes and prediabetes. CONCLUSIONS Diabetes and prediabetes were more prevalent among people aged over 45 years than in the general population. Da Nang has experienced a marked increase in the prevalence of prediabetes. These findings have significant implications regarding the need for nationwide public health interventions and management aiming at diabetes prevention and control.

OBJECTIVES: The prevalence of diabetes mellitus is rapidly increasing in Vietnam, particularly among adults aged over 45 years. This study estimated trends in diabetes and prediabetes prevalence and determined risk factors in Vietnamese adults (over 45 years). METHODS: A cross-sectional study was conducted based on data from an annual diabetes screening program among people aged 45-69 years in an urban city in central Vietnam (Da Nang). Joinpoint regression analyses were performed to calculate the annual percentage change and ptrend-values. Multinomial logistic regression analysis was used to determine risk factors. RESULTS: In total, 3,765 men and 9,149 women were included in this analysis. The age-adjusted prevalence of diabetes and prediabetes in 2017 was 11.4% and 52.9%, respectively. The prevalence of diabetes was higher in men (15.1%) than in women (10.3%), but that of prediabetes was similar in both genders (53.4% vs. 52.8%). The prevalence of prediabetes significantly increased during the study period, whereas no upward or downward trend for diabetes was observed. The prevalence of obesity, abdominal obesity, hypertension, and dyslipidemia showed no obvious trend. Obesity, a high waist-to-hip ratio, hypertension, more severe abdominal obesity, and dyslipidemia were significantly associated with a higher risk of diabetes and prediabetes. CONCLUSIONS Diabetes and prediabetes were more prevalent among people aged over 45 years than in the general population. Da Nang has experienced a marked increase in the prevalence of prediabetes. These findings have significant implications regarding the need for nationwide public health interventions and management aiming at diabetes prevention and control.