1.Delivery care in Chi Linh District,Hai Duong province
Chi Thu Thuy Tran ; Hoa Thi Phuong Dinh
Journal of Medical and Pharmaceutical Information 2004;0(8):22-25
Background: Maternal and child healthcare is a leading priority in the health care strategy of Viet Nam. Motherhood safety is amongst contents of reproductive healthcare strategy to ensure safe delivery, reduce maternal and neonatal morbidity as well as mortality. Aims: To discover the utilization of delivery care and related factors to women in selecting location for delivery. Subjects and method: The study was carried out in Chillilab \u2013 Demographic and Epidemiological Surveillance was set up in Chi Linh district, Hai Duong province by the School of Public Health. A combination of quantitative and qualitative methods was used in collecting the data. Results: 97% of pregnant women chose public health facilities as their delivery place and 2.5% of pregnant women had homebirths. The main reasons for delivery in hospitals were trust on care quality and sufficient equipment for emergency care. The complicated delivery rate was 14% and Cesarean section delivery was 12%. Hospitalized deliveries were more common in the women with higher education and/or better economic status. Conclusion: There should be improved healthcare communications to encourage all women to give birth at health facilities. Improving the quality of delivery care in community health stations is important to give opportunities for deprived women to receive safer deliveries.
Delivery
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Reproductive health
2.Expression of Heparansulfate Interacting Protein (HIP) in benign prostatic hyperplasia,prostate intraepithelial neoplasia and prostate cancer
Ngoc Thi Phuong Nguyen ; Thuy Thu Nguyen ; Chi Kim Dao ; Khanh Van Tran ; Van Thanh Ta
Journal of Medical Research 2008;56(4):98-104
Background: Heparansulfate Interacting Protein (HIP) is up-regulated in various human cancer cell lines at both transcript and protein levels. HIP expression is related to the differentiation status and cancer development. Objectives: To determine HIP in benign prostatic hyperplasia, prostatic intraepithelial neoplasia and prostate cancer tissues. Materials and method: Western blot method was used to determine HIP expression in 3 different types of prostate tissue, including 11 prostate cancer samples, 2 benign prostatic hyperplasia samples and 11 prostatic intraepithelial neoplasia samples. Results. HIP was particularly up-regulated in prostate cancer and prostatic intraepithelial neoplasia, indicating that up-regulation of HIP expression may be an early event in tumorgenesis. Conclusion: The expression of HIP was different between cancer, prostatic intraepithelial neoplasia tissue and benign prostatic hyperplasia. HIP may serve as a prognostic marker for prostate carcinoma.
HIP expression
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Prostate cancer
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Prostatic hyperplasia.
3.Occurrence of Fruit Rot of Melon Caused by Sclerotium rolfsii in Korea.
Jin Hyeuk KWON ; Tran Thi Phuong CHI ; Chang Seuk PARK
Mycobiology 2009;37(2):158-159
In 2007 to 2008, a fruit rot of Melon (Cucumis melo L.) caused by Sclerotium rolfsii occurred sporadically in a farmer's vinyl house in Jinju City. The symptoms started with watersoaking lesion and progressed into the rotting of the surface of fruit. White mycelial mats appeared on the lesion at the surface of the fruit and a number of sclerotia formed on the fruit near the soil line. The sclerotia were globoid in shape, 1~3 mm in size, and white to brown in color. The hyphal width was measured 3 to 8 microm. The optimum temperature for mycelial growth and sclerotia formation was 30 on PDA. Typical clamp connections were observed in hyphae of grown for 4 days on PDA. On the basis of symptoms, mycological characteristics and pathogenicity to the host plant, this fungus was identified as Sclerotium rolfsii Saccardo. This is the first report of the fruit rot of Melon caused by S. rolfsii in Korea.
Allyl Compounds
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Cucumis melo
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Cucurbitaceae
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Fruit
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Fungi
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Humans
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Hyphae
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Korea
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Plants
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Soil
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Sulfides
4.Soft Rot of Rhizopus oryzae as a Postharvest Pathogen of Banana Fruit in Korea.
Jin Hyeuk KWON ; Jae San RYU ; Tran Thi Phuong CHI ; Shun Shan SHEN ; Okhee CHOI
Mycobiology 2012;40(3):214-216
Soft rot on banana fruit caused by Rhizopus oryzae was identified for the first time in Korea. Colonies were white to light brown and formed numerous sporangiospores. Optimum temperature for mycelial growth was 30degrees C. Sporangia were globose and 30~200 microm. Sporangiophores were usually straight, 8~20 microm, and rhizoids usually in groups of 3~5. Columella were globose to sub-globose and 90~110 microm. Sporangiospores were sub-globose or oval and 4~10 microm. Based on its mycological characteristics, molecular analysis, and pathogenicity to host plants, this fungus was identified as Rhizopus oryzae Went & Prisen Geerligs. This is the first report of soft rot on banana caused by Rhizopus oryzae in Korea.
Fruit
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Fungi
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Humans
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Korea
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Light
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Musa
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Oryza
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Rhizopus
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Sporangia
5.Identification of Phenolic Compounds from Vietnamese Artichoke (Cynara scolymus L.) Leaf and Their Antioxidant Activities
Anh Nguyet Thi NGUYEN ; Thanh Tuyen Thi VU ; Hong Tuoi Thi DO ; Thien Hai NGUYEN ; Huan Van LE ; Hong Khuyen Thi PHAM ; Phu Chi Hieu TRUONG ; Dong Phuong PHAM ; Manh Hung TRAN
Natural Product Sciences 2024;30(1):39-51
Artichoke (Cynara scolymus L.) is a perennial plant belonging to the Asteraceae family originating from the Mediterranean region. In Vietnam, there are some varieties of artichoke which are extensively cultivated and propagated in highland areas, however, there have been limited detailed scientific publications on the chemical composition and biological activity of artichoke grown in Vietnam. Therefore, this study provides a detailed description of the extraction, isolation, and structural determination of 20 natural secondary metabolites present in harvested artichoke. The antioxidant activity of the extract and the 9 isolated compounds are tested in 1,1-diphenyl-2-picrylhydrazyl radical scavenging and ex vivo malondialdehyde model. Among the selected compounds, 1-caffeoylquinic acid, 3-caffeoylquinic acid, chlorogenic acid, 4-caffeoylquinic acid, cynarin, 1,5-dicaffeoylquinic acid, 4,5-di-caffeoylquinic acid, cynaroside, and scolymoside exhibited strong radical scavenging activity with IC50 values ranging from 5.7 to 61.6 µM. In the malondialdehyde assay, 1,3-dicaffeoylquinic acid (or cynarin) showed the strongest activity with an IC50 value of 24.7 µM, followed by 1,5-di-caffeoylquinic acid (66.8 µM), and 4,5-di-caffeoylquinic acid (127.3 µM). This outcome contributes to establishing a database on the phytochemical and antioxidant activity of the Vietnamese artichoke.
6.Evaluation of the positivity of the fecal occult blood test compared to the microscopic detection of red blood cells
Chi Cao LE ; Nu Phuong Anh TON ; Thi Minh Chau NGO ; Phuoc Vinh NGUYEN ; Thi Bich Thao DO ; Thi Ngoc Thuy HA ; Minh Tiep VO ; Thi Giang TRAN ; That Dong Duong TON
Hue Journal of Medicine and Pharmacy 2023;13(7):31-38
Backgrounds: Fecal occult blood testing (FOBT) is commonly used in colorectal cancer screening programs. Many studies have compared different FOBT methods, but the correlation between traditional red cell microscopy and FOBT remains unclear. Objectives: 1) To evaluate the rate of positive FOBT in patients with different disease groups; 2) To compare the sensitivity and specificity of red blood cells detection in fresh stool by microscopy technique and FOBT. Materials and methods: This was a cross-sectional study involving 120 patients from Hue University of Medicine and Pharmacy Hospital who requested a stool test from 4/2021 to 4/2022. Fresh stool samples were examined for the presence of red blood cells using traditional microscopy and FOBT technique. Results: The overall positivity rate of FOBT was 20%, and in the group of gastrointestinal diseases (n = 24), clinical anemia (n = 21), hepatobiliary diseases (n = 26) and other diseases (n = 49), it was 37.5%, 23.8%, 11.5% and 14.3%, respectively. In comparison with the FOBT technique, microscopic RBC detection had a sensitivity of 33.3% and a specificity of 100%. Conclusions: A high rate of fecal occult blood tests was observed in patients with gastrointestinal disorders. Microscopic erythrocyte detection has low sensitivity and many disadvantages compared to the rapid test. This rapid test should be widely used in clinical practice to aid in the diagnosis of gastrointestinal bleeding
7.Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
Lan Trong Phan ; Quang Chan Luong ; Thi Hong Hien Do ; Cindy H Chiu ; Thang Minh Cao ; Thao Thi Thanh Nguyen ; Hai Thanh Diep ; Thao Phuong Huynh ; Dung Tri Nguyen ; Nga Hong Le ; Satoko Otsu ; Phu Dac Tran ; Thuong Vu Nguyen ; Masaya Kato
Western Pacific Surveillance and Response 2019;10(2):22-30
Objective:
To document the evolution and optimization of the Zika virus (ZIKV) disease surveillance system in southern Viet Nam in 2016 and to describe the characteristics of the identified ZIKV-positive cases.
Methods:
We established a sentinel surveillance system to monitor ZIKV transmission in eight sites in eight provinces and expanded the system to 71 sites in 20 provinces in southern Viet Nam in 2016. Blood and urine samples from patients who met the case definition at the sentinel sites were tested for ZIKV using real-time reverse transcription polymerase chain reaction at the Pasteur Institute in Ho Chi Minh City (PI-HCMC). We conducted descriptive analysis and mapped the ZIKV-positive cases.
Results:
In 2016, 2190 specimens from 20 provinces in southern Viet Nam were tested for ZIKV at PI-HCMC; 626 (28.6%), 484 (22.1%), 35 (1.6%) and 1045 (47.7%) tests were conducted in the first, second, third and fourth quarters of the year, respectively. Of these tested specimens, 214 (9.8%) were ZIKV positive with 212 (99.1%) identified in the fourth quarter. In the fourth quarter, the highest positivity rate was those in age groups 30–39 years (30.0%) and 40–59 years (31.6%). Of the 214 ZIKV-positive patients, 210 (98.1%) presented with rash, 194 (90.7%) with fever, 149 (69.6%) with muscle pain, 123 (57.5%) with joint pain and 66 (30.8%) with conjunctivitis.
Discussion
The surveillance system for ZIKV disease underwent several phases of optimization in 2016, guided by the most up-to-date local data. Here we demonstrate an adaptable surveillance system that detected ZIKV-positive cases in southern Viet Nam.