1.Remarks on at Hospital 354- HaNoi
Journal of Practical Medicine 2003;463(10):85-87
Research 614 patients with gynecological bacterial infection remarks at Hanoi 354. Results: Growing in a culture (+) was 74% in which has 40,83% of fungus, 44,89% of bacteria, 14,19% of combine infection. Due to Gr (+) bacterium and Gr (-) gynecological bacterial infection rate was 90,77% (most of them was 50,03%) and 9,23% respectively. 100% strain of bacteria against antibiotic 1-14 were tried. Peniciliin, Amocillin, Cloramphenicol, trimethoptrim were sensitive with 4-40%. Immipenem was sensitive highly to Gr (+) and Gr (-) bacteria with 90-98%
Bacteria
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Bacterial Infections
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epidemiology
2.Detection of mutant dystrophin gene carrier using quantitative Polymerase Chain Reaction
Suong Thi Bang Nguyen ; Khanh Van Tran ; Hoan Thi Nguyen ; Ha Thi Nguyen ; Van Thanh Ta
Journal of Medical Research 2008;59(6):1-10
Background: Deletion and duplication mutations of dystrophin gene make up from 70 to 75% of patients with Duchenne Muscular Dystrophy (DMD). Two thirds of children with DMD inherited from the heterozygous mothers the mutated gene which is located on one of the sex chromosomes. Objective: To detect the asymptomatic carriers of dystrophin gene mutation using molecular techniques. Subject and methods: 3 DMD patients and their 9 relatives. Using techniques: DNA extraction and quantitative Polymerase Chain Reaction (PCR). Results: Successfully detected 4 heterozygous individuals from 9 female members of three different families that have already confirmed DMD patients. Conclusion: This method could lead to a new way of prenatal diagnosis of DMD as well as other genetic disorders that are caused by deletion or duplication mutation.
Duchenne muscular dystrophy
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carrier
;
quantitative PCR