The 2- hydroxy-4,6-dimethyl pyrimidine (8),2-amino-4,6 –dimethyl pyrimidine (10) and sulfamet-hazine(1)were prepared by condensation of urea (4), guanidine (5) or sulfaguanidine (6) with acetylacetone(7) and then the 2-chloro-4,6-dimethyl pyrimidine (9) was obtained by treating the compound (8) with phosphorylchoride (POCl3)
Biological Products ; chemistry ; pharmacy

From January 1994 to December 2003, at the Hospital 198, 697 patients (149 males, 548 females) with simple thyroid goiter, aged 16-75 years oldwere treated and operated. The age of highest incidence was 21-40 years old (79.92%). Thyroid cyst accounts for highest incidence 48.21%. According to WHO classification the incidence of surgery was mainly in the goiter of 2nd, 3rd grade. Anapathological analysis found the highest incidence 47.92% in simple colloid goiter. There were 4 cases of thyroid cancer (0.57%). General complications found in 2.44%.
Therapeutics ; Surgery ; Goiter ; Thyroid Gland

A case of teratoma in a male patient aged 53 years old at the liver left lobe, hospitalized 25 November 2002 at The Hospital 198 was persented. It was a special form of mature teratoma of dermoid cyst. Macroscopically, it was a cyst of large size with thick fibroid shell, containing fat fluid, caseinous matter, hair, cartilaginous bone and even 3 molar teeth. Microscopically, it was a lining of cells of keratinoid epithelial scale tissue in the wall. Under the epithelial cover there was a conjunctive tissue inserted by sebacenous tissues, sweat gland tissues, hair alveoli and vessels with thick fibrous wall.
Teratoma ; Liver ; Diagnosis ; Pathology ; History

45 patients with spleen trauma were treated in the hospital No 19-8. Among then, 17 underwent a prevervative operation for suturing the spleen according to the state of trauma in site, the surgeon's qualification and the follow- up conditions. The preservative suture must be safe, spleen function must be preserved, any spleen edge could be partialy removed in case of injury. Early result can be altained in 94,11% and early post operative complication in 5,89% of cases.
Abdominal Injuries ; Surgery ; Diagnosis

The study was performed on 727 currently working and retied officials in Thai Binh province to evaluate reality of hypertension. Results: the overall percentage of hypertension was 51% and tended to increase gradually by age- groups: < 60 years of age accounted for 8.8%; 60-70 years of age 14.7%; over 70 years of age 27.5%. The rate of hypertension in males was more than females. Hypertension level 1 accounted for 25.45%, level II 15.4% and level III 10.8%. The rate of hypertensive patients with left ventricular hypertrophy was 21%, coronary insufficiency 18.59% and heart rhythm disorder 3.5%. The rate of coronary insufficiency, left ventricular hypertrophy and heart rhythm disorder in hypertension level I group were 10.8%, 4.86%, 1.6%, respectively, lower than hypertension level II group (37.8%, 47.2%, 6.8%, respectively)
Hypertension ; Epidemiology

This study was carried out on 131 patients (101 women and 30 men) with surgery for thyroid cancer at University Hospital No 103 from 1995 though March 2002. 49 patients (37.4%) were operated for the thyroid pathology before hospital admission. Based on clinical examination and laboratory measurements, the authors found that the rate of thyroid cancer was 1-2% of all cancers. The rate of papillary thyroid carcinoma (PTC) was 62.6%, follicular (FTC): 19.8% medullary (MTC): 5.3%, squamous (STC): 2.3%, and nondifferentiated (NDTC) tumors: 9.9%. All surgical procedures were performed according to principal rules of oncologic surgery. 12 sternotomy and 5 tracheotomy during operation were performed. Accidental injuries of the esophagus (2 cases) and the trachea (3 cases) occur during the resection of tumor. After the surgical resection, the chemotherapy, radiotherapy, hormone therapy have been used in various combinations, one patient died and all survivors have been followed up
Thyroid Neoplasms ; Thyroid Gland ; Surgery ; diagnosis ; Therapeutics ; surgery

Rotavirus is one of the major causes of pediatric gastroenteritis and diarrhea. Based on the Rota/Adeno combistick one-step test for rotavirus and adenovirus in human feces, the authors studied causes of pediatric diarrhea. Some results: the rate of diarrhea induced Rotavirus accounted for 64.4%, mainly in children under 2 year of age. The highest prevalence of the rotavirus diarrhea is experienced in cool months of the year. Clinical symptoms were diarrhea and vomiting. Vomiting presented in 54.9% of cases.
Diarrhea ; Rotavirus

Severinia monophylla (L.) Tanaka was widely distributed in many northern provinces of Viet Nam. The plant was a good folk remegy for cold, fever, cough. Materials and methods: Leaves and fruits of S. monophylla were collected in Me Linh district (province of Vinh Phuc), and analysed for essential oil by using gas chromatography and mass spectrometry. Results: The yield of oil from leaves and fruits was 0.2% compared with air-dried materials. The main constituents of the oil included: caryophyllene (17.2%), sesquiphellandrene (15.1%) and alpha-caryophyllene (13.8%).
Tanaka ; Oils, Oil Chemical Composition

At the Hematology and Blood Transfusion Center Ho Chi Minh city. We have recently been performing collection, processing, and cryoprotection prior to freezing of cord blood for the first cord blood transplantation in Vietnam. The cord blood cells are sedimended by rouleaux formation using hydroxyethyl starch by gently centrifugation. The leukocyte-rich supematant is then transferred to a disposable processing bag set. The cells are then concentrated by a second centrifugation and removal of excess plasma supematant. The cryoprotection agent dimethyl sulfoxide is then slowly added to the concentrated cells, and the mixture transferred to a Themogenesis Corp, approved freezing bag for freezing and storage in the BioArchive System
Fetal Blood ; Freezing

Makers of HBV were investigated in the groups of acute and chronic hepatitis B and liver cirrhosis patients, using radioimmunological assays. 170 patients were followed up and treated in the Clinical Medicine Institute for Tropical Diseases during 1997 and 1998. Changes in HBsAg, anti-HBs, HBeAg, anti-HBe, anti-HBc and IgG markers were followed up.
Hepatitis B ; Fibrosis