Adenoma, Pleomorphic ; diagnosis ; pathology ; Humans ; Trachea ; pathology ; Tracheal Neoplasms ; diagnosis ; pathology

Adult ; Female ; Humans ; Lymphoma, Non-Hodgkin ; diagnosis ; pathology ; Tracheal Neoplasms ; diagnosis ; pathology

A 20-year-old man presented to our outpatient clinic with hemoptysis, cough, and pleuritic chest pain. His chest radiograph and pulmonary function tests (PFT) were normal. A bronchoscopy showed a small yellowish patch with a regular surface. A direct bronchoscopic biopsy was performed. The pathologic findings showed a benign granular cell tumor. The respiratory symptoms resolved after biopsying the tumor. On follow?up, there were no signs of recurrence of the granular cell tumor after a period of 24 months.
Adult ; Chest Pain/*diagnosis/pathology ; Granular Cell Tumor/*diagnosis/pathology ; *Hemoptysis ; Humans ; Male ; Tracheal Neoplasms/*diagnosis/pathology

A 47-year-old maIe, who had been treated under the diagnosis of bronchial asthma, was admitted to this department with the complaints of progressive dyspnea of 3 years duration and upper air way obstruction causing unique stridor. Through roentgenography and bronchoscopy, lower tracheal hamartoma was confirmed, but a pulmonary function test precipitated acute hypoxia with mental somnolence. The tumor was removed as quickly as possible by multiple punch biopsy, through a rigid bronchoscope, for life saving air way maintenance.
Biopsy ; Bronchoscopy ; Fiber Optics ; Hamartoma/diagnosis* ; Human ; Male ; Middle Age ; Respiratory Sounds/etiology* ; Trachea/pathology ; Tracheal Neoplasms/diagnosis*

OBJECTIVETo investigate the clinical characteristics of bronchial tumors in 3 children to improve the diagnosis of pediatric bronchial tumor.

METHODSThree cases of children bronchial malignant tumors diagnosed by rigid bronchoscopy were analyzed retrospectively.

RESULTSThe 3 children were males, aged from 6 to 10 years old, and presented with cough, sputum, and fever symptoms for 1 day to 3 months. Chest CT scan and airway remodeling examinations indicated the children's main bronchi were blocked and then the diagnoses of bronchial foreign bodies were made. However bronchial tumors were found in the 3 children by rigid bronchoscopy and were determined as mucoepidermoid carcinoma, large cell lung carcinoma with rhabdoid phenotype, and inflammatory myofibroblastic tumor, respectively.

CONCLUSIONSChildren with bronchial tumor often present with cough, wheezing and other respiratory symptoms that are not specific to bronchial tumor. When a child complaint of repeated cough and wheezing symptoms with unknown cause, not only bronchial foreign body and also bronchial tumor should be considered.

Bronchi ; pathology ; Bronchoscopy ; Carcinoma, Mucoepidermoid ; diagnosis ; Child ; Cough ; Foreign Bodies ; Humans ; Male ; Respiratory Sounds ; Retrospective Studies ; Tracheal Neoplasms ; diagnosis

OBJECTIVETo explore the treatment and prognosis on patients with tracheal invasion by papillary thyroid carcinoma (PTC).

METHODSForty-five patients treated for PTC with tracheal invasion between 1980 and 1995 were retrospectively analyzed. The different kinds of surgical modalities were performed according to the extent and degree of tracheal invasion by PTC. Neck dissect was performed in 39 patients. External beam radiotherapy was used postoperatively in patients with gross residual tumor or microscopic residual tumor in pathologic margins after resection. Survival was evaluated using the Kaplan-Meier method.

RESULTS(1) Twenty-eight patients with limited tracheal invasion were treated with shave excision, the 5- and 10-year survival rates were 85.0% and 62.6%, respectively. After a shave excision, the differences of 5- and 10-year survival rates between irradiated and nonirradiated patients were not statistically significant (P > 0.05). (2) Ten patients were radical excision for intraluminal involvement extending through the tracheal cartilage, including circumferential sleeve resection (4 cases), tracheal window resection (5 cases) and total laryngectomy (1 case), the survival rate was 80.0% for five years and 58.3% for ten years. After a radical excision, the differences of 5- and 10-year survival rates between irradiated and nonirradiated patients were not statistically significant (P > 0.05). (3) For 7 patients performing the palliative operation, the 5-and 10-year survival rates were 42.9% and 28.6%, respectively. For 4 patients received postoperative radiotherapy, the 5-and 10-year survival rates were 50.0% and 50.0%, respectively. Three patients didn't received postoperative radiotherapy, the 5-year survival rate was 33.3%, no patient survived for ten years. In these patients of incomplete resection, the differences of 5-and 10-year survival rates between irradiated and nonirradiated patients were not statistically significant (P > 0.05).

CONCLUSIONSPTC with limited involvement of the trachea could be treated successfully by shaving tumor off the tracheal cartilage. Intraluminal involvement extending through the tracheal cartilage could be resected radically in patients with PTC. Postoperative radiotherapy could improve the survival of the patients with PTC with tracheal invasion who have been performed incomplete resection.

Adult ; Aged ; Carcinoma, Papillary ; diagnosis ; pathology ; therapy ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Prognosis ; Retrospective Studies ; Survival Rate ; Thyroid Neoplasms ; diagnosis ; pathology ; therapy ; Trachea ; pathology ; Tracheal Neoplasms ; diagnosis ; secondary ; therapy

Primary tracheal tumours are rare and less frequently observed than bronchial tumours. Primary neurogenic tumours of the trachea as schwannomas or neurilemmomas are extremely uncommon. We report a tracheal schwannoma in a female patient who presented with breathlessness and wheeze, and she was being treated for asthma. Flexible bronchoscopy revealed a large pedunculated tracheal mass and biopsy confirmed schwannoma. She was treated with laser ablation with partial reduction of the tumour. Subsequently, she was lost to follow-up, although resection of the tumour with tracheal reconstruction was planned.
Adult ; Asthma ; diagnosis ; Biopsy ; Bronchoscopy ; Diagnosis, Differential ; Diagnostic Errors ; Dyspnea ; diagnosis ; etiology ; Female ; Follow-Up Studies ; Humans ; Neurilemmoma ; diagnosis ; surgery ; Radiography, Thoracic ; Reconstructive Surgical Procedures ; Respiratory Sounds ; diagnosis ; etiology ; Tomography, X-Ray Computed ; Trachea ; diagnostic imaging ; pathology ; surgery ; Tracheal Neoplasms ; diagnosis ; surgery