1.Extranodal Marginal Zone Lymphoma Occurring along the Trachea and Central Airway.
Ji Young KANG ; Hyun Jin PARK ; Kyo young LEE ; Sook Young LEE ; Seung Joon KIM ; Sung Hak PARK ; Young Kyoon KIM
Yonsei Medical Journal 2008;49(5):860-863
Extranodal marginal zone lymphoma is a low-grade B cell lymphoma that presents with an indolent clinicopathologic nature. Although this tumor can occur in various sites, including the gastrointestinal tract and lungs, it develops and spreads extremely rarely along the trachea and central airway. We report a case of extranodal lymphoma of mucosa-associated lymphoid tissue with tracheobronchial involvement. An 83-year-old woman presented with a cough and dyspnea. Bronchoscopic evaluation confirmed diffuse, multiple nodular lesions in both the trachea and large bronchi, and she was diagnosed with an extranodal marginal zone lymphoma of the tracheobronchial tree. After systemic chemotherapy, she survived for more than 18 months.
Aged, 80 and over
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Bronchial Diseases/drug therapy/*pathology/radiography
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Female
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Humans
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Lymphoma, B-Cell, Marginal Zone/drug therapy/*pathology/radiography
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Radiography, Thoracic
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Tracheal Diseases/drug therapy/*pathology/radiography
2.Evaluation of Tracheobronchial Diseases: Comparison of Different Imaging Techniques.
Qihang CHEN ; Jin Mo GOO ; Joon Beom SEO ; Myung Jin CHUNG ; Yu Jin LEE ; Jung Gi IM
Korean Journal of Radiology 2000;1(3):135-141
OBJECTIVE: To compare the clinical utility of the different imaging techniques used for the evaluation of tracheobronchial diseases. MATERIALS AND METHODS: Forty-one patients with tracheobronchial diseases [tuberculosis (n = 18), bronchogenic carcinoma (n = 10), congenital abnormality (n = 3), post-operative stenosis (n = 2), and others (n = 8)] underwent chest radi-ography and spiral CT. Two sets of scan data were obtained: one from routine thick-section axial images and the other from thin-section axial images. Multiplanar reconstruction (MPR) and shaded surface display (SSD) images were obtained from thin-section data. Applying a 5-point scale, two observers compared chest radiography, routine CT, thin-section spiral CT, MPR and SSD imaging with regard to the detection, localization, extent, and characterization of a lesion, information on its relationship with adjacent structures, and overall information. RESULTS: SSD images were the most informative with regard to the detection (3.95 +/-0.31), localization (3.95 +/-0.22) and extent of a lesion (3.85 +/-0.42), and overall information (3.83 +/-0.44), while thin-section spiral CT scans provided most information regarding its relationship with adjacent structures (3.56 +/-0.50) and characterization of the lesion (3.51 +/-0.61). CONCLUSION: SSD images and thin-section spiral CT scans can provide valuable information for the evaluation of tracheobronchial disease.
Bronchial Diseases/*radiography
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Comparative Study
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Female
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Human
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*Imaging, Three-Dimensional
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Male
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Middle Age
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*Tomography, X-Ray Computed/methods
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Tracheal Diseases/*radiography
3.Unusual Combination of Tracheobronchopathia Osteochondroplastica and AA Amyloidosis.
Gokhan KLRBAS ; Canan Eren DAGLL ; Abdullah Cetin TANRLKULU ; Fetin YLLDLZ ; Yasar BUKTE ; Abdurrahman SENYIGIT ; Esen KLYAN
Yonsei Medical Journal 2009;50(5):721-724
Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of unknown cause characterized by the presence of multiple submucosal osseous and/or cartilaginous nodules that protrude into the lumen of the trachea and large bronchi. A simultaneous diagnosis of TO and amyloidosis is rarely reported. In this report, a case initially suspected to be asthma bronchiole that could not be treated, was radiologically diagnosed as TO, and also secondary amyloidosis is presented. A 53 years, man patient reported a 3 years history of dyspnea. Pulmonary function tests (PFTs) showed an obstructive pattern. Chest X-rays revealed right middle lobe atelectasis. FOB and CT detected nodular lesions in the trachea and in the anterior and lateral walls of the main bronchi. AA amyloidosis was confirmed by endobronchial biopsy. In the abdominal fat pad biopsy, amyloidosis was not detected. Asthma bronchiole was excluded by PFTs. This case illustrates that it is possible for TO and amyloidosis to masquerade as asthma. TO and amyloidosis should be suspected in patients of older ages with asthma and especially with poorly treated asthmatic patients. Although nodular lesions in the anterior and lateral tracheobronchial walls are typical for TO, a biopsy should be obtained to exclude amyloidosis.
Amyloidosis/complications/*diagnosis/pathology
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Asthma/diagnosis
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Bronchial Diseases/complications/*diagnosis/radiography
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Diagnosis, Differential
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Humans
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Male
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Middle Aged
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Tracheal Diseases/complications/*diagnosis/radiography
4.Ultrasonographic evaluation of tracheal collapse in dogs.
Kidong EOM ; Kumjung MOON ; Yunsang SEONG ; Taeho OH ; Sungjoon YI ; Keunwoo LEE ; Kwangho JANG
Journal of Veterinary Science 2008;9(4):401-405
Tracheal ultrasonography was performed to measure the width of the tracheal ring shadow and to assess the clinical relevance of these measurements for identifying tracheal collapse. The first tracheal ring width (FTRW) and thoracic inlet tracheal ring width (TITRW) were measured on both expiration and inspiration. The mean of the FTRW width (129 dogs) was greater in expiration (10.97 +/- 1.02 mm, p = 0.001) than that in inspiration (9.86 +/- 1.03 mm). For 51 normal dogs, the mean of the TITRW width was greater in expiration (9.05 +/- 1.52 mm, p = 0.001) than in inspiration (8.02 +/- 1.43 mm). For 78 tracheal collapse dogs, the mean of the TITRW width was greater in expiration (15.89 +/- 1.01 mm, p = 0.001) than in inspiration (14.85 +/- 1.17 mm). The TITRW/FTRW ratio of the normal dogs was higher (p = 0.001) in expiration (0.81 +/- 0.09) than that in inspiration (0.79 +/- 0.10). When compared between the normal and tracheal collapse dogs, the TITRW/FTRW ratio was also increased (p = 0.001) both in expiration (1.54 +/- 0.09) and inspiration (1.47 +/- 0.08), respectively. Based on these results, the cutoff level of the TITRW/FTRW ratio was statistically analyzed according to the receiver operating characteristic curve and it could be set at 1.16 in expiration and at 1.13 in inspiration. We have demonstrated that tracheal ultrasonography is a useful technique for the evaluation of tracheal collapse and it can be a supportive tool together with the radiographic findings for making the correct diagnosis.
Animals
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Dog Diseases/diagnosis/pathology/*ultrasonography
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Dogs
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Female
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Male
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Radiography, Thoracic/*veterinary
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Sensitivity and Specificity
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Trachea/*pathology/radiography
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Tracheal Stenosis/diagnosis/pathology/veterinary
5.Laryngo-tracheobronchial amyloidosis: a case report and review of literature.
Jing-xia WANG ; Shan YANG ; Hai-hong CHEN ; Qin-ying WANG ; Yu-yu LU ; Li-Li JIANG
Chinese Medical Sciences Journal 2014;29(1):48-50
AMYLOIDOSIS is a benign process which can have systemic involvement. Though larynx is the common site of localized amyloidosis in the head and neck region,1 it was seldom reported with heterochronous implication of bilateral ventricles. Here we report a case of laryngeal amyloidosis heterochronously localized at bilateral ventricles with tracheobronchial involvement. Combined with our experience we reviewed the literature, and discuss the pertinent managements of this condition.
Adult
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Amyloidosis
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diagnostic imaging
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pathology
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surgery
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Bronchial Diseases
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diagnostic imaging
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pathology
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surgery
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Humans
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Laryngeal Diseases
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diagnostic imaging
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pathology
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surgery
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Laryngoscopy
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Male
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Radiography
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Tomography Scanners, X-Ray Computed
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Tracheal Diseases
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diagnostic imaging
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pathology
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surgery
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Treatment Outcome
6.Keutel syndrome with tracheal stenosis as the major symptom: case report and literature review.
Li-feng SUN ; Yun-fei JU ; Guo-jing FU ; Jin-rong WANG ; Yi-zhen FENG ; Xing CHEN
Chinese Journal of Pediatrics 2013;51(7):527-530
OBJECTIVETo investigate the clinical characteristics, diagnosis and therapy of Keutel syndrome, and thereby to minimize the misdiagnosis.
METHODData of a case of Keutel syndrome diagnosed at the Provincial Hospital Affiliated to Shandong University were analyzed and related literature were reviewed.
RESULTAn 8-month-26-day-old boy was presented with inspiratory and expiratory stridor and wheezing after movement on lung auscultation. His craniofacial appearance was characterized by midfacial hypoplasia with a broad depressed nasal bridge. The nose was small and flat. A grade 2-3/6 systolic murmur was heard between the second and third ribs at left edge of the sternum. The end phalanges of his fingers were thickened. Chest radiograph showed tracheobronchial cartilage calcification and tracheobronchial stenosis. Echocardiographic examination revealed the right pulmonary stenosis. With endoscopic surgery, antiobstructive and antibiotic therapy clinical symptoms were improved. Three weeks later he died of lung reinfection after he was discharged from our hospital. English literature search with "Keutel syndrome" as the key word at "PubMed" showed 22 articles covering 26 patients, and the clinical symptoms were hearing loss (91%), persistent respiratory symptoms (68%), recurrent otitis media/sinusitis (67%), growth development delay (52%) in turn, and signs were brachytelephalangism (100%), low nasal bridge (95%), midfacial hypoplasia (93%), cardiac murmur (69%), and auxiliary examinations showed abnormal cartilage calcification (100%), pulmonary arterial stenosis (72%), tracheobronchial stenosis (50%).
CONCLUSIONThe diagnosis of Keutel syndrome should be considered in patients with brachytelephalangism, abnormal cartilage calcification, peripheral pulmonary stenosis, and midfacial hypoplasia. Tracheal stenosis was main clinical manifestation in part of patients.
Abnormalities, Multiple ; diagnosis ; diagnostic imaging ; therapy ; Bone and Bones ; diagnostic imaging ; Calcinosis ; diagnosis ; diagnostic imaging ; therapy ; Cartilage ; diagnostic imaging ; Cartilage Diseases ; diagnosis ; diagnostic imaging ; therapy ; Diagnosis, Differential ; Hand Deformities, Congenital ; diagnosis ; diagnostic imaging ; therapy ; Humans ; Infant ; Male ; Pulmonary Valve Stenosis ; diagnosis ; diagnostic imaging ; therapy ; Radiography, Thoracic ; Retrospective Studies ; Tomography, X-Ray Computed ; Tracheal Stenosis ; diagnosis ; diagnostic imaging