No abstract available.
Toxoplasmosis*

The authors have recently experienced 2 cases of ocular texoplasmosis which had poor vision. These cases were presumptive diagnosis of ocular toxoplasmosis by typical ocular lesion and hemmagglutinin test for toxoplasmosis. In addition to clinical observations, a brief review of literature has been described.
Diagnosis ; Toxoplasmosis ; Toxoplasmosis, Ocular*

No abstract available.
Toxoplasma* ; Toxoplasmosis*

We report a literature review and a case of ocular toxoplasmosis in a patient with multiple drug allergies, who was successfully treated with regular intravitreal clindamycin and subconjunctival dexamethasone. A Malay lady in her twenties presented to us with right eye blurring of vision of 2 weeks duration, which she described as a central scotoma. Visual acuity at presentation was hand movements. Examination revealed intense ocular inflammation. The right eye had anterior segment inflammation of 3+ cells with fine keratic precipitates, whilst the posterior segment revealed papillitis, vitritis, retinitis, choroiditis, vasculitis and hyperpigmented chorioretinal scar inferotemporal to fovea. Ocular coherence tomography showed intraretinal fluid and retinal thickening. Fluorescein angiography showed early hypofluorescence of the lesion with progressive hyperfluorescence and leakage from the optic disc. Immunoglobulin G serology of Toxoplasma gondii was raised and immunoglobulin M levels were normal. The patient developed an allergic reaction with classical antibiotic and antifolate therapy. She was successfully treated with regular two-weekly intravitreal clindamycin and subconjunctival dexamethasone and her best corrected visual acuity was 6/18 at the end of her treatment. Intravitreal injection of clindamycin and subconjunctival dexamethasone is a good option in patients of ocular toxoplasmosis who are allergic to oral medications.
Toxoplasmosis, Ocular

The authors have recently experienced 3 cases of ocular toxoplasmosis. The diagnosis was based on typical ocular lesions and hemagglutination test for toxoplasmosis. In addition to some clinical observations, a brief review of literature has been described.
Diagnosis ; Hemagglutination Tests ; Toxoplasmosis ; Toxoplasmosis, Ocular*

No abstract available.
Glioblastoma* ; HIV* ; Toxoplasmosis, Cerebral*

A 36-year-old-male was admitted complaining of headache, right sided weakness and numbness of upper and lower extremity, and multiple cranial nerve deficits. Cranial magnetic resonance imaging revealed an abscess in the pontomesencephalic junction. Patient was then diagnosed to have Human Immunodeficiency Virus with a CD 4 count of 32 cells/ uL, his CSF assay was positive for Toxoplasmosis IgG and was managed as a case of probable brainstem toxoplasmosis. Patient was treated with Co-Trimoxazole 800/160mg 2 tablets twice a day. Upon discharge the patient clinically improved and was tolerating oral feeding. A repeat cranial magnetic resonance imaging after 6 weeks of antibiotic treatment revealed a decrease of size in the previous lesion. To our knowledge, there are no reported cases in the Philippines that shows the documentation of CNS toxoplasmosis in the brainstem. In this paper, a case of CNS toxoplasmosis in the pons of a newly diagnosed HIV patient is presented and how its course led to a good outcome.
Toxoplasmosis ; Immunocompromised Host

Humans ; Infant ; Male ; Toxoplasmosis ; etiology

No abstract available.
Drug Therapy, Combination ; Female ; Human ; Infant ; Male ; Serologic Tests ; Toxoplasma/immunology ; Toxoplasmosis, Congenital/complications ; Toxoplasmosis, Congenital/diagnosis ; Toxoplasmosis, Congenital/pathology*

A total of 421 patients hospitalized in St. Mary's Hospital were examined by indirect latex agglutination test in order to evaluate the Toxoplasma antibody in Korean from June to August 1981. The test sera of the patients were obtained from each age group by random sampling. The 421 samples of test sera showed negative in 153, 1:2 in 157, 1:4 in 59, 1:8 in 27, 1:16 in 7, 1:32 in 9, 1:64 in 2, 1:128 in 4 and 1:256 in 3 cases, respectively. The positive rate of Toxoplasma antibody was 4.3 percent in this sample when indirect latex antibodies of 1:32 or higher were regarded as positive. The titers of positive Toxoplasma antibodies were increased by age.
parasitology-protozoa ; Toxoplasma gondii ; toxoplasmosis ; immunology ; diagnosis