1.A Rare Cause of Peripheral Vascular Thrombosis: Hypereosinophilia Caused by Toxocara canis Infection.
Jeung Hui PYO ; Byoung Ju MIN ; Min Seon PARK ; Dae Hoe KU ; Chang Ho JUNG ; Jae Kyeom SIM ; Hye Sook MIN
Korean Journal of Medicine 2014;86(6):781-784
Hypereosinophilia is often associated with eosinphilic infiltration of tissue, which can lead to severe and irreversible organ damage. One of the most characteristic and critical complications is development of thrombosis in cardiac ventricles, and occasionally in deep veins. We report a rare case of hypereosinophilia, with peripheral vascular thrombosis, caused by Toxocara canis infection.
Heart Ventricles
;
Thrombosis*
;
Toxocara canis*
;
Toxocariasis
;
Veins
2.Experimental study on the effect of cortisone in mice infected with Toxocara canis: Histopathological findings of granuloma in the liver.
The Korean Journal of Parasitology 1974;12(2):126-134
The present study was carried out to examine the effect of "Cortisone" on the worm burden migrated in the organs, and granulomatous change in the liver of mice infected with Toxocara canis eggs. Daily does of 0.5 mg "Cortisone" was administrated subcutaneously to Toxocara-infected mice with different schedule. The results are summarized as follows: More number of Toxocara larvae migrated into the muscle tissue, especially into the carcass through the wall of the large intestine and higher distribution rate and longer persistence of worms were also recognized in the carcass of the experimental group than in the control. Cortisone administration resulted the inhibition of granuloma formation, as well as the resolution of granuloma in the liver. However, the discontinuation of the administration induced the reccurence of heavier grade of inflammation. In non-cortisone treated group (control), cellular infiltration appeared around the worms in the liver on the 10th day of the infection, and typical granulomatosis was followed on the 20th day. As in above results, it is considered cortisone has remarkable anti-inflammatory and immunosuppressive effects in mice infected with T.canis, but histopathological changes on the granuloma formation might be related closely with the duration of Toxocara infection, dosage, duration and timing of cortisone administration.
parasitology-helminth-nematoda-Toxocara canis
;
liver
;
mouse
;
cortisone
3.Cardiac Involvement in Hypereosinophilia Associated with Toxocariasis.
Hyun Joon PARK ; Ga In YOU ; Kyoung Im CHO ; Joung Wook YANG ; Soo Young KIM ; Hyun Su KIM ; Tae Joon CHA
Journal of Cardiovascular Ultrasound 2014;22(4):224-227
Cardiac involvement in hypereosinophilia is rare; when present, it manifests as ventricular thickening, usually with fibrous tissue and mural thrombosis. We present a case of a 57-year-old man with an abnormal right ventricular apex with eosinophilia, which was caused by Toxocara canis infection.
Echocardiography
;
Eosinophilia
;
Humans
;
Middle Aged
;
Thrombosis
;
Toxocara canis
;
Toxocariasis*
4.A Case of Eosinophilic Pleural Effusion Caused by Toxocariasis without Serum Eosinophilia.
Min Ji CHO ; Ju Ock KIM ; Sung Soo JUNG ; Hee Sun PARK ; Da Hyun KANG ; Dong Il PARK
Soonchunhyang Medical Science 2015;21(2):173-175
Human toxocariasis is a parasitic disease caused by Toxocara canis or Toxocara cati. We report a patient with toxocariasis who presented with dyspnea and left pleural effusion. All patients with toxocariasis in published case reports had serum eosinophilia. This is the first case report of eosinophilic pleural effusion without serum eosinophilia caused by toxocariasis infection, which was confirmed by using enzyme-linked immunosorbent assay (ELISA). Therefore, an antibody ELISA can be useful for diagnosing toxocariasis in patients with a pleural effusion of unknown cause, even in the absence of serum eosinophilia.
Dyspnea
;
Enzyme-Linked Immunosorbent Assay
;
Eosinophilia*
;
Eosinophils*
;
Humans
;
Parasitic Diseases
;
Pleural Effusion*
;
Toxocara
;
Toxocara canis
;
Toxocariasis*
5.The anti-parasitic efficacy of ivermectin and pyrantel pamoate compound against canine Toxocara canis and Trichuris vulpis.
Heejeong YOUN ; Jeong Chan RA ; Byung Ki KIM ; Bokyoung BAE ; Yong Suk LIM ; Kyong Hee KIM ; Kyong Eun LEE
Korean Journal of Veterinary Research 2011;51(4):289-295
Toxocara (T.) canis and Trichuris (T.) vulpis are very important canine parasitic nematodes. T. canis parasitize in small intestine and T. vulpis parasitize in large intestine. In order to control of these nematodes, ivermectin and pyrantel pamoate compound was applied to the dogs infected with these parasites naturally and artificially. This drug was composed of 68.0 microg of ivermectin and 57.0 mg of pyrantel pamoate for small animal, 136.0 microg of ivermectin and 114.0 mg of pyrantel pamoate for middle animal, and 272.0 microg of ivermectin and 227.0 mg of pyrantel pamoate for large animal. Ivermectin in this drug is activity to nematodes and ectoparisites. Pyrantel pamoate in this drug is also activity to nematodes. In this experiment, this drug had a good efficacy against T. canis and T. vulpis in the infected dogs.
Animals
;
Dogs
;
Intestine, Large
;
Intestine, Small
;
Ivermectin
;
Parasites
;
Pyrantel
;
Pyrantel Pamoate
;
Toxocara
;
Toxocara canis
;
Trichuris
6.Eosinophilic Myocarditis Associated with Visceral Larva Migrans Caused by Toxocara Canis Infection.
Ji Hee KIM ; Woo Baek CHUNG ; Kyung Yoon CHANG ; Sun Young KO ; Mi Hee PARK ; Young Kyoung SA ; Yun Seok CHOI ; Chul Soo PARK ; Man Young LEE
Journal of Cardiovascular Ultrasound 2012;20(3):150-153
A 41-year-old woman who was diagnosed with myocarditis presented eosinophilia. Since the antibody against Toxocara canis (T. canis) was positive, we diagnosed that she had visceral larva migrans due to T. canis associated with myocarditis. She was treated with oral albendazole and prednisolone for two weeks, eosinophil count and hepatic enzymes were normalized after completion of treatment. This is the first report of myocarditis caused by T. canis infection in Korea.
Adult
;
Albendazole
;
Eosinophilia
;
Eosinophils
;
Female
;
Humans
;
Korea
;
Larva Migrans, Visceral
;
Myocarditis
;
Prednisolone
;
Toxocara
;
Toxocara canis
7.A Case of Toxocariasis with Visceral Larva Migrans Combined with Ocular Larva Migrans.
Ji Eun PARK ; Mi Jung OH ; Dong Hyun OH ; In Myung OH ; Kyoung Hwa YOO ; Sung Gyu IM ; Hyun Kyung GHIL
Korean Journal of Medicine 2012;83(4):543-549
Toxocariasis is an infection in a human host caused by Toxocara canis or Toxocara cati larvae. Clinical manifestations are classified according to the organs affected, such as visceral larva migrans (VLM) and ocular larva migrans (OLM). Epidemiological evidence suggests that OLM tends to occur in the absence of systemic involvement and vice versa, which has led to two manifestations of this infection being reclassified as VLM and OLM. No case of a patient with VLM combined with OLM has been reported in Korea. Here, we report a case of VLM combined with OLM in a 51-year-old female caused by massive ingestion of raw cow meat, manyplies, and liver.
Eating
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Female
;
Humans
;
Korea
;
Larva
;
Larva Migrans
;
Larva Migrans, Visceral
;
Liver
;
Meat
;
Middle Aged
;
Toxocara
;
Toxocara canis
;
Toxocariasis
8.Toxocara canis-Associated Myelitis with Eosinophilic Pneumonia.
Kee Hong PARK ; Young Soo KIM ; Soo Kyung KIM ; Nack Cheon CHOI ; Oh Young KWON ; Byeonghoon LIM ; Ki Jong PARK
Experimental Neurobiology 2016;25(3):139-142
The existence of Toxocara canis-specific antibodies has recently been reported in patients with atopic myelitis. Here, we report the case of a 35-year-old male patient admitted with a chief complaint of right lower limb hypoesthesia lasting for a month. The patient was diagnosed with eosinophilic pneumonia 3 months ago, and a spine MRI revealed the presence of myelitis in the cervicothoracic cord. After confirming the presence of hyper-IgE-emia and Toxocara canis antibodies, the patient was treated with steroids and albendazole treatment, which improved his symptoms. To our knowledge, this is the first case of Toxocara canis-associated myelitis with eosinophilic pneumonia.
Adult
;
Albendazole
;
Antibodies
;
Eosinophils*
;
Humans
;
Hypesthesia
;
Lower Extremity
;
Magnetic Resonance Imaging
;
Male
;
Myelitis*
;
Pulmonary Eosinophilia*
;
Spine
;
Steroids
;
Toxocara canis
;
Toxocara*
9.Foodborne Eosinophilia due to Visceral Larva Migrans: A Disease Abandoned.
Journal of Korean Medical Science 2012;27(1):1-2
No abstract available.
Animals
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Eosinophilia/*etiology
;
Humans
;
Larva Migrans, Visceral/*complications/diagnosis/epidemiology
;
Prevalence
;
Toxocara canis/isolation & purification
10.Studies on the intradermal reactions with the fractions of Ascaris lumbricoides.
The Korean Journal of Parasitology 1967;5(1):17-34
The intradermal studies with the fraction of Ascaris lumbricoides and Toxocara canis were performed to human and dog, and the following results were observed. Wheal and erythema were appeared in the cases of ascaris infection or who had past history, but not in the ascaris free before. The size of wheal reached to peak 30 minutes after the injection. The crude antigen had specificity and showed no cross reaction. The crude antigen cause the strongest and largest reaction than the other substances; protein, polysaccharide and the mixed antigen. No cutaneous reaction was observed with the fraction of polysaccharides. The size of wheal did not parallel with the worm burden. The skin reaction was appeared four weeks after the infection.
parasitology-nematode-Ascaris lumbricoides
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Toxocara canis
;
immunology-crude antigen-skin test
;
dog
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protein
;
polysaccharide
;
antigen