An 87-year-old man was admitted complaining of cough after he had been treated with drugsat another hospital. Chest X-ray revealed multiple nodules, and chest computed tomography(CT) showed metastatic lung tumors. Abdominal CT revealed staining of the outer portion ofthe prostate by contrast medium, though this finding was considered nonspecific andnondiagnostic. A CT-guided biopsy of a lung tumor was performed, and the lung tumor wasfound to be positive for prostate-specific antigen (PSA). Prostate carcinoma was diagnosedby prostate biopsy, which yielded the same findings as the lung tumor. The serum PSA levelwas high. No metastases except for pulmonary lesions were observed on a bone scintigramand abdominal CT. Prostate carcinoma with pulmonary metastases alone was thereforediagnosed. The present case represents a rare case of pulmonary metastases without anyother metastases.

An 87-year-old man was admitted complaining of cough after he had been treated with drugs at another hospital. Chest X-ray revealed multiple nodules, and chest computed tomography (CT) showed metastatic lung tumors. Abdominal CT revealed staining of the outer portion of the prostate by contrast medium, though this finding was considered nonspecific and nondiagnostic. A CT-guided biopsy of a lung tumor was performed, and the lung tumor was found to be positive for prostate-specific antigen (PSA). Prostate carcinoma was diagnosed by prostate biopsy, which yielded the same findings as the lung tumor. The serum PSA level was high. No metastases except for pulmonary lesions were observed on a bone scintigram and abdominal CT. Prostate carcinoma with pulmonary metastases alone was therefore diagnosed. The present case represents a rare case of pulmonary metastases without any other metastases.

We report a case of adenocarcinoma detected in the right pleural effusion of a 75-year-old woman. Investigations failed to reveal the site of the primary lesion, and the case was treated as primary unknown cancer. The pleural effusion disappeared after chemotherapy; however, as there was serious bone marrow suppression, the clinical course was observed at an outpatient clinic without chemotherapy. A search for the primary lesion was repeated, but it was not found. One year after first admission, a chest X-ray showed left pleural effusion. Adenocarcinoma was detected in the effusion and a tumor mass obtained from the pleural cavity. Ovarian cancer was diagnosed based on the histological, serological and MRI findings. Thus, this was a rare case of ovarian cancer in which the diagnosis was confirmed by repeated evaluation and in which the initial diagnosis had been primary unknown cancer with malignant pleural effusion only.
Ovarian Cancer ; Pleural Effusion, Malignant ; Pleural Effusion ; Unknown ; Beginning