1.Establishing Optimal Treatment for Osteoporotic Vertebral Fracture Based on Quantitative Evaluation of Vertebral Body Instability Using Dynamic Radiographs at Initial Visit
Toru FUNAYAMA ; Toshinori TSUKANISHI
Journal of the Japanese Association of Rural Medicine 2017;65(5):932-939
In a study involving 43 patients with osteoporotic vertebral fracture aged ≥ 65 years, three different therapeutic methods were designed based on a quantitative evaluation of vertebralbody instability that used dynamic radiographs taken at the initial visit. Vertebral body instability was defined as the difference between the percentage ratio of vertebral collapse (%) in the standing position and that in the supine position. When the difference was ≤ 5%, no bed rest was prescribed and ambulation was permitted as soon as a Jewett-type hard corset was ready (approximately 1 week). When the difference was between >5% and <20%, 2 weeks of bed rest was prescribed, after which ambulation while wearing the corset was permitted. When the difference was ≥ 20%, 2 weeks of bed rest was prescribed followed by ambulation, but when pain persisted or rehabilitation showed no progress, treatment was changed to surgery. At 3 months after starting treatment, bone union, degree of improvement of pain, activities of daily living, and quality of life were evaluated. Findings showed that almost satisfactory treatment outcomes were achieved with all three treatment approaches. These findings suggest that while priority should be given to conservative treatment based on a quantitative evaluation of vertebral body instability, the possibility of surgery should also be considered. Particularly in cases with ≥ 20% difference in the percentage ratio of vertebral collapse, surgical interventionat a relatively early stage may help reduce to zero the potential for delayed union, pseudarthrosis, and delayed paralysis.
2.Tumor Occupation in the Spinal Canal and Clinical Symptoms of Cauda Equina Schwannoma: An Analysis of 22 Cases.
Kengo FUJII ; Masataka SAKANE ; Tetsuya ABE ; Tsukasa NAKAGAWA ; Shinsuke SAKAI ; Masaki TATSUMURA ; Toru FUNAYAMA ; Masashi YAMAZAKI
Asian Spine Journal 2016;10(6):1079-1084
STUDY DESIGN: Retrospective, radiological study. PURPOSE: To determine the relationship between clinical symptoms and the extent of tumor occupation of the spinal canal by cauda equina schwannoma. OVERVIEW OF LITERATURE: Little is known about the relationship between the size of tumors of the cauda equina and the manifestation of clinical symptoms. We analyzed this relationship by estimating the percentage of tumor occupation (PTO) in the spinal canal in cauda equina schwannomas and by correlating this parameter with the presence and severity of clinical symptoms. METHODS: Twenty-two patients (9 men and 13 women; age, 19–79 years; mean age, 55.3 years) who were radiologically diagnosed with schwannomas of the cauda equina between April 2004 and July 2014 were retrospectively analyzed. PTO was measured in axial and sagittal magnetic resonance imaging slices in which the cross-sectional area of the tumor was the largest. Data regarding clinical symptoms and results of physical examinations were collected from patient medical records. PTO differences between symptom-positive and -negative groups were analyzed for each variable. RESULTS: In the 4 cases in which tumor presence was not related to clinical symptoms, PTO was 5%–10% (mean, 9%) in axial slices and 23%–31% (mean, 30%) in sagittal slices. In the 18 cases in which symptoms were associated with the tumor, PTO was 11%–86% (mean, 50%) in axial slices and 43%–88% (mean, 71%) in sagittal slices. PTO in axial slices was significantly higher in the presence of Déjèrine symptoms and/or muscle weakness, a positive straight leg raise test, and a positive Kemp sign. CONCLUSIONS: PTO >20% in axial slices and >40% in sagittal slices can be an indication of symptomatic cauda equina schwannoma.
Cauda Equina*
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Female
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Humans
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Leg
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Magnetic Resonance Imaging
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Male
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Medical Records
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Muscle Weakness
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Neurilemmoma*
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Occupations*
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Physical Examination
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Retrospective Studies
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Spinal Canal*
3.Characteristics of Lumbar Spondylolysis in Adolescent Baseball Players: Relationship between the Laterality of Lumbar Spondylolysis and the Throwing or Batting Side
Shotaro TERUYA ; Toru FUNAYAMA ; Masaki TATSUMURA ; Hisanori GAMADA ; Shun OKUWAKI ; Takeo MAMMOTO ; Atsushi HIRANO ; Masashi YAMAZAKI
Asian Spine Journal 2024;18(2):260-264
Methods:
The study included 85 players. Participants were divided into two groups: pitchers and fielders. The association between the laterality of spondylolysis and the throwing/batting side in the overall cohort and between the two groups was evaluated.
Results:
Among pitchers, 16 lesions appeared on the throwing side and 32 on the nonthrowing side (p =0.029). For fielders, no notable difference was observed between the two sides (p =0.363). Furthermore, batting preference did not influence the laterality of spondylolysis in either group.
Conclusions
Adolescent baseball players, particularly pitchers, exhibited a higher incidence of lumbar spondylolysis on the side opposite their throwing arm. The findings of this study highlight the significant effect of asymmetrical sporting activities on the development of spondylolysis, to which pitchers are particularly susceptible.
4.Successful Use of the Hybrid Assistive Limb for Care Support to Reduce Lumbar Load in a Simulated Patient Transfer
Kousei MIURA ; Hideki KADONE ; Tetsuya ABE ; Masao KODA ; Toru FUNAYAMA ; Hiroshi NOGUCHI ; Hiroshi KUMAGAI ; Katsuya NAGASHIMA ; Kentaro MATAKI ; Yosuke SHIBAO ; Kosuke SATO ; Hiroaki KAWAMOTO ; Yoshiyuki SANKAI ; Masashi YAMAZAKI
Asian Spine Journal 2021;15(1):40-45
Methods:
Nineteen volunteers (16 men, three women) lifted a 60-kg doll from a seated position to a standing position. The first transfer was performed without the HAL for Care Support, and the second was performed with the HAL for Care Support assistive robot. We evaluated transfer performance, the visual analog scale (VAS) score for lumbar fatigue, and electromyogram analyses of the trunk and hip.
Results:
Four participants (two men, two women) succeeded with the HAL for Care Support even though they were unable to perform the task without it. The mean lumbar fatigue VAS score for all participants without the HAL for Care Support was 62 mm, while that with it was 43 mm. With lumbar assistance from the HAL for Care Support, subjective lumbar fatigue during the transfer decreased significantly. A power analysis indicated adequate statistical power to detect a difference in the VAS score for lumbar fatigue (0.99). The activity of the left gluteus maximus alone increased significantly during transfers with the HAL for Care Support. No adverse events occurred during use of the HAL for Care Support for transfers.
Conclusions
The HAL for Care Support was able to reduce lumbar load in a simulated patient transfer.
5.Exploring factors affecting activities of daily living in patients with osteoporotic vertebral fractures managed conservatively: a post-hoc analysis of a prospective cohort study
Toru FUNAYAMA ; Masaki TATSUMURA ; Kengo FUJII ; Yosuke SHIBAO ; Shun OKUWAKI ; Kotaro SAKASHITA ; Takahiro SUNAMI ; Kento INOMATA ; Hisanori GAMADA ; Kousei MIURA ; Hiroshi NOGUCHI ; Hiroshi TAKAHASHI ; Masao KODA ; Masashi YAMAZAKI
Asian Spine Journal 2024;18(4):570-578
Methods:
A total of 224 consecutive patients with OVFs aged ≥65 years who received treatment within 2 weeks after the occurrence of injury were enrolled. The patients were followed up for 6 months thereafter. The criteria for evaluating the degree of independence were applied to evaluate ADLs. Multivariable analysis with a logistic regression model was performed to evaluate the risk factors for ADL decline.
Results:
In total, 49/224 patients (21.9%) showed a decline in ADLs. Of these, 23/116 patients (19.8%) in the rest group and 26/108 patients (24.1%) in the no-rest group experienced a decline in ADLs. In the logistic regression analyses, a diffuse low signal on T2- weighted magnetic resonance imaging (MRI) (odds ratio, 5.78; 95% confidence interval, 2.09–16.0; p=0.0007) and vertebral instability (odds ratio, 3.89; 95% confidence interval, 1.32–11.4; p=0.0135) were identified as independent factors in the rest and no-rest groups, respectively.
Conclusions
In patients with acute OVFs, a diffuse low signal on T2-weighted MRI and severe vertebral instability were independently associated with ADL decline in patients treated with and without initial bed rest, respectively.
6.Exploring factors affecting activities of daily living in patients with osteoporotic vertebral fractures managed conservatively: a post-hoc analysis of a prospective cohort study
Toru FUNAYAMA ; Masaki TATSUMURA ; Kengo FUJII ; Yosuke SHIBAO ; Shun OKUWAKI ; Kotaro SAKASHITA ; Takahiro SUNAMI ; Kento INOMATA ; Hisanori GAMADA ; Kousei MIURA ; Hiroshi NOGUCHI ; Hiroshi TAKAHASHI ; Masao KODA ; Masashi YAMAZAKI
Asian Spine Journal 2024;18(4):570-578
Methods:
A total of 224 consecutive patients with OVFs aged ≥65 years who received treatment within 2 weeks after the occurrence of injury were enrolled. The patients were followed up for 6 months thereafter. The criteria for evaluating the degree of independence were applied to evaluate ADLs. Multivariable analysis with a logistic regression model was performed to evaluate the risk factors for ADL decline.
Results:
In total, 49/224 patients (21.9%) showed a decline in ADLs. Of these, 23/116 patients (19.8%) in the rest group and 26/108 patients (24.1%) in the no-rest group experienced a decline in ADLs. In the logistic regression analyses, a diffuse low signal on T2- weighted magnetic resonance imaging (MRI) (odds ratio, 5.78; 95% confidence interval, 2.09–16.0; p=0.0007) and vertebral instability (odds ratio, 3.89; 95% confidence interval, 1.32–11.4; p=0.0135) were identified as independent factors in the rest and no-rest groups, respectively.
Conclusions
In patients with acute OVFs, a diffuse low signal on T2-weighted MRI and severe vertebral instability were independently associated with ADL decline in patients treated with and without initial bed rest, respectively.
7.Exploring factors affecting activities of daily living in patients with osteoporotic vertebral fractures managed conservatively: a post-hoc analysis of a prospective cohort study
Toru FUNAYAMA ; Masaki TATSUMURA ; Kengo FUJII ; Yosuke SHIBAO ; Shun OKUWAKI ; Kotaro SAKASHITA ; Takahiro SUNAMI ; Kento INOMATA ; Hisanori GAMADA ; Kousei MIURA ; Hiroshi NOGUCHI ; Hiroshi TAKAHASHI ; Masao KODA ; Masashi YAMAZAKI
Asian Spine Journal 2024;18(4):570-578
Methods:
A total of 224 consecutive patients with OVFs aged ≥65 years who received treatment within 2 weeks after the occurrence of injury were enrolled. The patients were followed up for 6 months thereafter. The criteria for evaluating the degree of independence were applied to evaluate ADLs. Multivariable analysis with a logistic regression model was performed to evaluate the risk factors for ADL decline.
Results:
In total, 49/224 patients (21.9%) showed a decline in ADLs. Of these, 23/116 patients (19.8%) in the rest group and 26/108 patients (24.1%) in the no-rest group experienced a decline in ADLs. In the logistic regression analyses, a diffuse low signal on T2- weighted magnetic resonance imaging (MRI) (odds ratio, 5.78; 95% confidence interval, 2.09–16.0; p=0.0007) and vertebral instability (odds ratio, 3.89; 95% confidence interval, 1.32–11.4; p=0.0135) were identified as independent factors in the rest and no-rest groups, respectively.
Conclusions
In patients with acute OVFs, a diffuse low signal on T2-weighted MRI and severe vertebral instability were independently associated with ADL decline in patients treated with and without initial bed rest, respectively.
8.Exploring factors affecting activities of daily living in patients with osteoporotic vertebral fractures managed conservatively: a post-hoc analysis of a prospective cohort study
Toru FUNAYAMA ; Masaki TATSUMURA ; Kengo FUJII ; Yosuke SHIBAO ; Shun OKUWAKI ; Kotaro SAKASHITA ; Takahiro SUNAMI ; Kento INOMATA ; Hisanori GAMADA ; Kousei MIURA ; Hiroshi NOGUCHI ; Hiroshi TAKAHASHI ; Masao KODA ; Masashi YAMAZAKI
Asian Spine Journal 2024;18(4):570-578
Methods:
A total of 224 consecutive patients with OVFs aged ≥65 years who received treatment within 2 weeks after the occurrence of injury were enrolled. The patients were followed up for 6 months thereafter. The criteria for evaluating the degree of independence were applied to evaluate ADLs. Multivariable analysis with a logistic regression model was performed to evaluate the risk factors for ADL decline.
Results:
In total, 49/224 patients (21.9%) showed a decline in ADLs. Of these, 23/116 patients (19.8%) in the rest group and 26/108 patients (24.1%) in the no-rest group experienced a decline in ADLs. In the logistic regression analyses, a diffuse low signal on T2- weighted magnetic resonance imaging (MRI) (odds ratio, 5.78; 95% confidence interval, 2.09–16.0; p=0.0007) and vertebral instability (odds ratio, 3.89; 95% confidence interval, 1.32–11.4; p=0.0135) were identified as independent factors in the rest and no-rest groups, respectively.
Conclusions
In patients with acute OVFs, a diffuse low signal on T2-weighted MRI and severe vertebral instability were independently associated with ADL decline in patients treated with and without initial bed rest, respectively.
9.Accidental anterior longitudinal ligament rupture during lateral lumbar interbody fusion disclosed after posterior corrective fusion surgery resulting in local hyper-lordosis
Yosuke SHIBAO ; Masao KODA ; Tetsuya ABE ; Kentaro MATAKI ; Kousei MIURA ; Hiroshi NOGUCHI ; Hiroshi TAKAHASHI ; Toru FUNAYAMA ; Masashi YAMAZAKI
Journal of Rural Medicine 2021;16(2):111-114
Objective: To report a case of anterior longitudinal ligament (ALL) injury that was not noticeable during lateral lumbar interbody fusion and was disclosed after posterior corrective fusion surgery.Case presentation: After performing lateral lumbar interbody fusion followed by posterior corrective fusion surgery, we observed an anterior longitudinal ligament rupture that required additional surgery. Postoperative pain in the left lower limb and muscle weakness due to nerve traction appeared, but this was improved by stabilization between the vertebral bodies.Conclusion: Unidentified anterior longitudinal ligament rupture can result in unexpected local lordosis during posterior surgery, possibly related to lower extremity palsy. Therefore, checking for possible rupture during and after anterior surgery is important. If the ALL damage is disclosed before posterior surgery, the proper surgical strategy for the posterior surgery must be considered.
10.Effects of conservative treatment of 2-week rigorous bed rest on muscle disuse atrophy in osteoporotic vertebral fracture patients
Akira IKUMI ; Toru FUNAYAMA ; Sho TERAJIMA ; Satoshi MATSUURA ; Akihiro YAMAJI ; Yuko NOGAMI ; Shun OKUWAKI ; Haruo KAWAMURA ; Masashi YAMAZAKI
Journal of Rural Medicine 2021;16(1):8-13
Objective: Osteoporotic vertebral fracture (OVF) is conventionally treated with conservative management such as bed rest, but a relatively prolonged bed rest has the potential risk of muscle disuse atrophy. This study aimed to examine whether the 2-week of rigorous bed rest affects muscle disuse atrophy in OVF patients.Patients and Methods: A total of 54 OVF patients (16 males; 38 females; mean age, 80.2 ± 9.2 years) were treated with an initial 2-week rigorous bed rest by hospitalization with persistent rehabilitation. Cognitive function, swallowing function, grip strength, and lower extremity circumference were evaluated at three-time points (admission, end of bed rest, and discharge).Results: Of the 51 patients who were able to walk independently before the injury, one patient (2.0%) had to use a wheelchair after the injury. During hospitalization, cognitive function decline was observed in 33.3% of patients, but not in patients with Revised Hasegawa’s Dementia Scale score ≥25 at admission. Swallowing function decline was observed in one patient, and none of the patients developed aspiration pneumonia during hospitalization. The grip strength significantly improved both at the end of bed rest (P=0.04) and discharge (P=0.02). Although the lower extremity circumference significantly decreased at the end of bed rest (P<0.01), it was recovered afterward. The lower extremity circumference did not significantly differ between the admission and discharge (P=0.17).Conclusion: Our results suggested that conservative treatment of OVF through an initial 2-week rigorous bed rest with persistent hospital rehabilitation poses a low risk of muscle disuse atrophy. If cognitive dysfunction is observed on admission, close monitoring for exacerbation should be performed during the hospital stay.