In recent years, with the in-depth research on intestinal microecology, probiotics, probiotics, synbiotics, fecal bacteria transplantation and other microecological therapies have become new clinical treatment and intervention methods. The occurrence and development of some chronic diseases are closely related to the disorder of intestinal flora. Therefore, in clinical practice, the treatment and adjuvant treatment of chronic dis-eases related to intestinal flora disorder with the method of intestinal microecology will bring better treatment op-tions and clinical prognosis. How to better regulate intestinal flora to bring more benefits to such patients, as well as what kind of microecologics and treatment methods are the primary problems and challenges in the inter-vention of chronic diseases with microecologics. Based on the current trend of intestinal microecological inter-vention in chronic diseases, this article proposedthe microecological intervention strategy, in order to improve theunderstanding of this topic.

Seeing that there are several defects in the calibration target currently used in C-arm-based surgical navigation system, we propose an improved design of calibration target based on the theory of generalized mapping. The method of design is introduced, the analysis is made, and the results are reported. The newly designed calibration target is of low manufacturing difficulty and cost; with the new calibration target, the running efficiency and the image quality of the whole navigation system could be improved. The new calibration target is found to be of several advantages over the currently used ones; it is feasible and is under manufacturing already.
Calibration ; standards ; Computer-Aided Design ; Equipment Design ; Image Processing, Computer-Assisted ; instrumentation ; Surgery, Computer-Assisted ; instrumentation ; Tomography, X-Ray Computed ; instrumentation