1. Epidemiological analysis on a family cluster of COVID-19
Yuanying QIU ; Songqiang WANG ; Xiaoli WANG ; Weixia LU ; Dan QIAO ; Jianbin LI ; Yuanyuan GU ; Yan ZENG ; Ying CHEN ; Weizhi BAI ; Bianli XU ; Tongwu HAN
Chinese Journal of Epidemiology 2020;41(4):506-509
Objective:
To understand the possible transmission route of a family cluster of COVID-19 in Zhengzhou and the potential infectivity of COVID-19 in incubation period, and provide scientific evidence for the timely control of infectious source and curb the spread of the epidemic.
Methods:
Epidemiological investigation was conducted for a family cluster of COVID-19 (8 cases) with descriptive epidemiological method, and respiratory tract samples of the cases were collected for the nucleic acid detection of 2019-nCoV by RT-PCR.
Results:
Two primary cases, which occurred on 31 January and 1 February, 2020, respectively, had a common exposure history in Wuhan. The other six family members had onsets on 30 January, 31 January, 1 February (three cases) and 3 February, 2020.
Conclusions
In this family cluster of COVID-19, six family members were infected through common family exposure to the 2 primary cases. Five secondary cases had onsets earlier than or on the same day as the primary cases, indicating that COVID-19 is contagious in incubation period, and the home isolation in the early phase of the epidemic might lead to the risk of family cluster of COVID-19.