The study course of carrier material for bioengineered corneal endothelium generally goes through a circulation of natural material-artificial material-natural material and attains valuable satisfactory and dissatisfactory experience.The early used materials include heterologous cornea.collagen,gelatin membrane,hydrogel,polyglycolic acid.poly lacticoglycolic acid,and so on.Corneal stroma/posterior elastic membrane,amniotic basilar membrane.corneal stroma.and poly-biomembrane are current study botspots.The further development in this field is to improve the cytophile,immunogenicity,and biodegradation.It is necessary to investigate the long-term effeCt on human body so as to promote the clinical application of cultivated corneal endothelium transplantation in the future.