1.Effect of extracted liquid from qianlietongyu on the proliferation and apoptosis on prostatic smooth muscle cells in vitro.
Tong-Wen CHNE ; Chun-Hua DENG ; Jian-Zhong LIU ; Rong-Hui CHNE ; He-Liang CHEN ; Wen-Feng WANG ; Hong ZHOU ; Jin-Mei LIU ; Xiao-Hong ZHANG ; Ying XIONG
National Journal of Andrology 2006;12(2):186-188
OBJECTIVETo explore the effect of extracted liquid from Qianlietongyu on the proliferation or apoptosis on prostatic smooth muscle cells in vitro.
METHODSAfter extracted liquid from Qianlietongyu treated the cultured prostatic smooth muscle cells, the anti proliferative and apoptotic indices were assessed by MTT assy and terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) respectively.
RESULTSThere was a significant dose-effect relationship between the concentration of extracted liquid from Qianlietongyu and the antiproliferative index on prostatic smooth muscle cells in vitro (P < 0.01), but there was no markedly difference in the apoptosis index between the group of extracted liquid from Qianlietongyu and control group ( P > 0.05).
CONCLUSIONExtracted liquid from Qianlietongyu may show significant antiproliferative effect on prostatic smooth muscle cells in vitro, without inducing apoptosis.
Apoptosis ; Cell Proliferation ; Cells, Cultured ; Humans ; Male ; Myocytes, Smooth Muscle ; drug effects ; Plant Extracts ; pharmacology ; Prostate ; cytology ; drug effects
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