1.Case of perianal herpes zoster complicated with dysuria.
Chinese Acupuncture & Moxibustion 2015;35(9):916-916
Acupuncture Therapy
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Aged
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Dysuria
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etiology
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physiopathology
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therapy
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Herpes Zoster
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complications
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virology
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Herpesvirus 3, Human
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physiology
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Humans
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Male
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Perineum
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virology
3.Effect of Helicobacter Pylori on Gastric Motor Function in Children with Chronic Gastrictis
tong-tong, PAN ; zhang, XU ; hui, XU ; xiao-qing, ZHOU
Journal of Applied Clinical Pediatrics 2006;0(19):-
Objective To explore the influence of helicobacter pylori(Hp) on gastric motor function in children with chronic gastrictis.Methods Forty-seven children with chronic gastrictis were classified into Hp positive and negative groups according to Hp and histology exa-mination.Each child underwent gastric emptying test of solid by using nuclide method and electrogastrogram(EGG) examination.These cases with Hp-positive acceptted these triple eradication therapy[clarithromycin 15 mg/(kg?d),amoxicillin 50 mg/(kg?d),omeprazole 0.8 mg/(kg?d)]for 2 weeks,and underwent EGG examination again after eradicating Hp.Results The half emptying time(GET_1/2)in Hp-positive gastric group were significantly longer than those in Hp-negative group(t=6.403 P
4.Multi-factor analysis of umbilical plasma ?-endorphin levels in neonates
Xuefeng ZHANG ; Hui SHENG ; Xiaomei TONG
Chinese Journal of Perinatal Medicine 1998;0(02):-
Objective To study the levels of umbilical plasma ?-endorphin (?-EP) in normal and abnormal pregnancy and the influencing factors. Methods The umbilical plasma ?-EP concentrations of 95 cases were measured by radioimmunoassay. Linear regression was used to find out the influencing factors of ?-EP including: neonatal gestational age, gender, birth weight, mode of delivery, maternal hypertension, maternal diabetes, premature rupture of membranes(PROM) and fetal distress. The subjects were divided into two groups: healthy term newborns and preterm neonates. Results Gestational age, mode of delivery and fetal distress were important factors influencing umbilical blood ?-EP production (P
5.Analysis of clinical characteristics of primary gastrointestinal melanoma in China
Tong ZHANG ; Hui LIU ; Yan YAN
China Journal of Endoscopy 2016;22(9):47-51
Objective To investigate the clinical manifestations, endoscopic manifestations, histological characteristics, diagnosis and treatment of the primary gastrointestinal melanoma in China. Methods The gender, age, position, endoscopic manifestations, histological characteristics, treatment, prognosis of the primary gastrointestinal melanoma were gathered and analyzed by reviewing retrospectively the data of 2 cases seen at our hospital and 449 cases searched in CNKI from 1983 to 2015. Results The primary gastrointestinal melanoma was mostly seen in the rectum and anus, and secondly in the esophagus. A typical endoscopic finding was a protuberant or nodular tumor, with erosion or dirty surface on it. Most lesions were friable and easily hemorrhagic. The maximum diameters of most lesions, accounted for 83.3 %, were larger than 2.0 cm. The average value of the maximum diameters was (4.79 ± 2.67) cm. Most cases presented brown or black, followed by hoar. However, some lesions presented various colors, such as blue, red, even co-exited color or achromatic color. Preoperative misdiagnosed rate was 73.64 % and 1-year mortality was 54.19 %. Negative correlation was observed between survival time and lesion size, infiltration depth. Positive correlation was observed between lesion size and metastasis infiltration depth. Survival time had nothing to do with metastasis and age. Conclusion The primary gastrointestinal melanoma was highly aggressive, and usually found in the terminal age, usually together with extensive metastasis, misdiagnosed and poor prognosis. Knowing the clinical features, endoscopic manifestations, histological and immunohistochemical characteristics is the key to early diagnosis.
6.Relationship between different degrees of asymptomatic carotid artery stenosis and cognitive impairment
Hui YU ; Cheng ZHANG ; Dezhang TONG
The Journal of Practical Medicine 2015;31(23):3850-3853
Objective To investigate relationship between different degrees of asymptomatic carotid artery stenosis and cognitive impairment. Methods The cognitive function were evaluated with the montreal cognitive assessment scale (MoCA) in 80 patients with asymptomatic carotid artery stenosis and 56 controls, the total MoCA scores and subprojects scores were compared between the patients with different degrees of ACS and controls. Results The total MoCA score, visual space and executive function, attention and delayed recall had significant difference among the mild, moderate, severe ACS patients and control group (all P < 0.05). There was no statistical significance of the total MoCA score and the scores of all subprojects between the patients of mild ACS patients and the control group (all P > 0.05). The total MoCA score and the scores of visual space and executive function , attention and delayed recall in moderate and severe ACS patients were significantly lower than the control group and mild ACS patients (P < 0.05). Furthermore, the severe ACS patients, compared with the moderate ACS patients , performed worse on the cognitive tasks which involved visual space and executive function, attention and delayed recall (P < 0.05). Conclusions Cognitive function is impaired in the patients with moderate and severe ACS,the neuropsychological characteristics are mainly impaired in visual space and executive function, attention and delayed recall.
7.Mechanisms of resistance to crizotinib in patients with transforming EML4-ALK fusion gene.
Hui-juan ZHANG ; Xiao-tong ZHANG ; Li ZHANG
Chinese Journal of Pathology 2012;41(12):862-864
Apoptosis
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drug effects
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Benzoquinones
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pharmacology
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Carcinoma, Non-Small-Cell Lung
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drug therapy
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metabolism
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pathology
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Drug Resistance, Neoplasm
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HSP90 Heat-Shock Proteins
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antagonists & inhibitors
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Humans
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Lactams, Macrocyclic
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pharmacology
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Lung Neoplasms
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drug therapy
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metabolism
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pathology
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Mutation
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Oncogene Proteins, Fusion
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antagonists & inhibitors
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genetics
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metabolism
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Protein Kinase Inhibitors
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therapeutic use
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Pyrazoles
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therapeutic use
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Pyridines
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therapeutic use
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Triazoles
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pharmacology
8.Myoglandular hamartoma of stomach: report of a case.
Jing ZHANG ; Zhao-hui LU ; Tong-hua LIU
Chinese Journal of Pathology 2011;40(12):843-844
Actins
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metabolism
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Adenocarcinoma
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pathology
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Adult
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Diagnosis, Differential
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Endometriosis
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pathology
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Epithelium
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pathology
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Female
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Gastrointestinal Stromal Tumors
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pathology
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Hamartoma
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metabolism
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pathology
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Humans
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Muscle, Smooth
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pathology
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Stomach Diseases
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metabolism
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pathology
9.Research progress of related genes in Xinjiang Kazakh' s esophageal cancer
Hui GUO ; Jianbing DING ; Wei SUN ; Tong ZHANG
Basic & Clinical Medicine 2010;30(4):428-430
Kazakh of Xinjiang is the region with a high incidence of esophageal cancer,genetic research is quite active in recent years.Through the research on biological activity of P53,RB gene during esophageal cancer process.We tried to find potential differences in the national heredity susceptibility and so to support treatment and the research.
10.Anti-tumor activity of emodin on human pancreatic cancer cell line BXPC-3 in vivo
Hongfei TONG ; Haiduo LIN ; Wei ZHANG ; Hui CHEN ; Shengzhang LIN
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(08):-
Objective: To investigate the effect and mechanism of emodin (EMO) on human pancreatic cancer cell line BxPC-3 in vivo. Methods: After the pancreatic cancer model in nude mice was established, the mice were divided into four groups: control group (NS 0.2mL/d by i.p. injection), EMO group (EMO 40mg?kg-1?d-1 by i.p. injection), and Gemcitabine (GEM) group (GEM 80mg/kg, twice/week by i.p. injection) with 8 mice each group. After 2 weeks of administration, the mice were sacrificed, detected the body-weight change of nude nice before and after the experiment, and recorded the growth inhibition rate of tumor (TGI). Immunohistochemical (IHC) staining for ki-67 and terminal deoxynucleotidyl transferase-mediated nicked labeling assay (TUNEL) were undertaken to detect the cell proliferation and cell apoptosis in tumor tissue in xenograft nude mice. Results: The inter-group comparisons in body-weight of nude mice showed no significant difference in comparing group NS(27.0?1.64)g with group EMO(25.1?1.58)g and GEM(25.6? 1.47)g.The EMO group was 38.46%, the GEM group was 44.23%. The inter-group comparisons in immunohistochemical analysis of ki-67 showed significant difference in comparing group NS IOD(219.5?17.98) with group EMO IOD(146.6? 11.57)and GEM IOD(139.5?12.55), (P