1.Impact of Coronavirus Disease 2019 on Prognosis and Treatment Strategies in Patients with Hematological Malignancy--Review.
Tong-Ai LENG ; Chen YANG ; Li WANG ; Chun-Ji GAO
Journal of Experimental Hematology 2022;30(2):645-648
Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide since outbreak in December 2019, and become a global public health crisis. Patients with hematological malignancy concurrently infected with COVID-19 are often associated with severe even fatal complications, due to low basic immune function, high intensity of chemotherapy and radiotherapy, and slow immune reconstruction post hematopoietic stem cell transplantation, and their treatment strategies, such as anti-infective therapy, blood transfusion, and the use of granulocyte colony stimulating factor need to be adjusted. The characteristics of patients, chemotherapy, hematopoietic stem cell transplantation, and other clinical factors may affect the prognosis of patients with hematological malignancy concurrently infected with COVID-19. Herein, the latest research progress is reviewed.
COVID-19
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Granulocyte Colony-Stimulating Factor/therapeutic use*
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Hematologic Neoplasms/drug therapy*
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Hematopoietic Stem Cell Transplantation/adverse effects*
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Humans
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Prognosis